Protein Alignment NfI and nfi-1

DIOPT Version :9

• Sequence 1: NP_995592.2
• Gene: NfI / 43782
• FlyBaseID: FBgn0042696
• Length: 766
• Species: Drosophila melanogaster
• Sequence 2: NP_001367580.1
• Gene: nfi-1 / 174225
• WormBaseID: WBGene00003592
• Length: 823
• Species: Caenorhabditis elegans
• Alignment Length: 819
• Identity: 224/819 - (27%)
• Similarity: 348/819 - (42%)
• Gaps: 215/819 - (26%)

  Fly    23 SSSGQDEFHPFIEALLPYVKSFSYSWFNLQAAKRKYYKKHEKRMSLEEERHCKDELQNEKTEVKQ 87
            |...|::..||:|.|||:|::.:|:||:||||||:::|:.:|:|...||.....||||::.|:|.
 Worm    65 SPYSQEDMGPFVEQLLPFVRASAYNWFHLQAAKRRHFKEFDKKMCASEENAKLAELQNDRDELKV 129

  Fly    88 KWASRLLGKLRKDITQESREDFVQSIIGKRKSICVLSNPDQKGKMRRIDCLRQADKVWRLDLVMV 152
            |||||||||::|||..:.:|.|:.:|.|...:.|::|..||||||||||||||||||||||||.:
 Worm   130 KWASRLLGKIKKDIQNDDKEAFISAINGSEPNKCIISVADQKGKMRRIDCLRQADKVWRLDLVTI 194

  Fly   153 ILFKAIPLESTDGERLEKNPECLHPGLCVNPYHINVSVRELDLYLANFINTHNSINNTNTTFSTT 217
            ||||.||||||||||||::..|:|| ||:||:|:.:|||.||:::||:      :.:.:|..:.|
 Worm   195 ILFKGIPLESTDGERLERSEACVHP-LCINPFHMAISVRGLDVFMANY------LKDVDTKITLT 252

  Fly   218 -PGVRSPHITMYNRSNDPNRKDEVADMKNDVVKQNP-YNGVVCNDIILATGVFSSQELWTLSKDL 280
             |                 |.||::|  ..:|||.| ...:|....:|.|. .:...:|
 Worm   253 YP-----------------RNDELSD--TVMVKQEPGEQTIVAPHAVLGTS-STHTRVW------ 291

  Fly   281 ILDESNDINLNSSLIKRENVGATYE----CNTY----QINSESSISAAQSLVQSGSIAAN----- 332
               |:|      |....|.:..||:    |:||    ...::.|:||..:.:.:.:...|
 Worm   292 ---ETN------SERNAETIIITYDPQKACHTYFGGRATLAQQSLSAGNTYMVNKTAVDNNFFNA 347

  Fly   333 ----------------PIPLGYSIDFIDQRITQLSQS--------PLPRTEGPNGDSHD-ANKID 372
                            |.|:..:.|.....:::.|..        .:...:.||..::| ..:|.
 Worm   348 KRSVLCLPPPPIQNCFPYPIAGTSDSQQMDMSEDSNDGPSEKRSRDISSHDSPNSSTNDEVRRIV 412

  Fly   373 QSSSPPI-------------TSTASDNGTSSFSLIVR-ATDSSIEDPKTSPISLHRYTS------ 417
            :|.:..:             :.|..:.|....|..|| ..|...:|...|| ...|.|:
 Worm   413 ESGTEKLVLGSSIWAAPGQFSRTQQNQGAPGTSRQVRPLPDFQSQDSARSP-GAFRSTAKPVCRM 476

  Fly   418 --------------LSSRTLAQAL-PQHSCSLLHSSSTSPTNTLYYPQHNNTRPSQTTSVE---- 463
                          :..|.....: .||..:.|.|..|:|:............|..:.|.|
 Worm   477 TVNTGNHGDVGVVVVDERNREHVIHAQHIVNALSSLRTTPSMRESPVGRKRMHPHTSNSFEFLNC 541

  Fly   464 --EQNR----VGSDKYSTEPQDISDFVT-----YVCQDTSHTTTITGSAENHSFQHSHTLPQGHG 517
              |.|:    :|||...|... :|:.::     |:...|..|   |...:..||.
 Worm   542 NQEMNKNEGALGSDISPTHTA-VSNLISRESSGYMASPTKFT---TARGDTTSFS---------- 592

  Fly   518 HSPHFQIHQQLRSAKLT-TSPSTHY-HSTMLPPMLP--------PMARPVAI--IRSSSDLTLVQ 570
                 :|.|::....|. ..|||.| :|.:.||:|.        .:..|||:  |.|..: :::.
 Worm   593 -----KIFQKIEEKHLQHNQPSTSYCNSQIQPPILSSKPVDSSVKLIAPVAVKPIMSGCN-SIIP 651

  Fly   571 SPPTSLPLTAQSTSLNDNSCIAKHSLPTDNRLASNLDNRNSPNNTDVVSQHEMTGTASPQPQSHT 635
            ||.|:..:|.....|.|:|.|        |.|.....:.:.....|...||.:      ...|.:
 Worm   652 SPITTPRITPSFRMLEDDSLI--------NVLGQLAHSNDGTTLNDSFIQHLI------DTNSRS 702

  Fly   636 PTLASPQSYLDPGRCKLLSAGSNIGRITTQMYPSSNNREYFNHFHSQPTSLLGYAGSISTMSGVI 700
            |.|:|..::      ..||.|:..|     :.|.       |..|...:|....:.|:....|:.
 Worm   703 PLLSSGNAF------SALSMGAVSG-----LVPG-------NSIHRPDSSASNGSNSLGVAMGLA 749

  Fly   701 SPTDLTL------------------YSAPMAVSRSSTRT 721
            .|.::.|                  ..||.|.|.||:.:
 Worm   750 VPQNIALAVQQTQNAMSPLHQIRVSVGAPPACSPSSSNS 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NfI	NP_995592.2	NfI_DNAbd_pre-N	25..64	CDD:287494	18/38 (47%)
		MH1	85..193	CDD:260161	70/107 (65%)
nfi-1	NP_001367580.1	NfI_DNAbd_pre-N	69..106	CDD:371114	18/36 (50%)
		MH1	128..231	CDD:397329	67/103 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167515
Domainoid	1	1.000	146	1.000	Domainoid score	I2811
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5305
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000997
OrthoInspector	1	1.000	-	-		oto18580
orthoMCL	1	0.900	-	-		OOG6_106071
Panther	1	1.100	-	-	LDO	PTHR11492
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3993
SonicParanoid	1	1.000	-	-		X590
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.820