DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP102A and chn1

DIOPT Version :9

Sequence 1:	NP_001245416.1	Gene:	RhoGAP102A / 43781	FlyBaseID:	FBgn0259216	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_998165.1	Gene:	chn1 / 406273	ZFINID:	ZDB-GENE-040426-1934	Length:	459	Species:	Danio rerio

Alignment Length:	429	Identity:	98/429 - (22%)
Similarity:	169/429 - (39%)	Gaps:	110/429 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   678 WYPSEHFLWISESGESFQIVETNLTRLSKIESDIVKNFALEKIQELNIGNIED------LKISPQ 736
            :|..:||:..........:|...|..|      .::..|.|.|.::.|..|.:      |...|.
Zfish    98 FYDGKHFVGEKRFESIHDLVTDGLITL------YIETKAAEYISKMTINPIYEHVGYTTLNREPA 156

  Fly   737 KRRCVPKKKSLTTSFFDNGK---KDDQNPRSVLFGTSLECCLERDSKRNVTMEDRS---KYS--- 792
            .::.:|..|.|     .:||   .:|......|  |||        .|..|:::..   ||.
Zfish   157 LKKTLPVCKDL-----PDGKHSPAEDSGLEERL--TSL--------VRRATLKESERVPKYEKVH 206

  Fly   793 --LLSMFRGSGSTPGSVLKLNDNVRSCE-------SLPSKSLEYGSTELSAYVRGS--FSNISKP 846
              .:..|||.              ..||       .|.::.::.....|:.:.:.|  ..|..||
Zfish   207 NFKVHTFRGP--------------HWCEYCANFMWGLIAQGVKCADCGLNVHKQCSKMVPNDCKP 257

  Fly   847 -LASLSQSENEDTELNFVKAYQEHSQLMVPIFVNNCIDYLEDNGLQQVGLFRVSTSKKRVKQLRE 910
             |..:.:..:.|. ...|||:....    |:.|:.||..:|..|||..||:|:|.....::.::.
Zfish   258 DLKHVKKVYSCDL-TTLVKAHNAKR----PMVVDMCIREIEARGLQSEGLYRISGFSDLIEDVKL 317

  Fly   911 EFDKD---------IYFGISVDTCPHDVATLLKEFLRDLPEPLLCNTLYLTFLKTQRIRNRRLQL 966
            .||:|         :|..|:|      ::..||.:.||||.|::....|..|::..::.:...:|
Zfish   318 SFDRDGEKADISVNVYEDINV------ISGALKLYFRDLPIPVITYDAYPRFIQAAKLTDPDERL 376

  Fly   967 EAISHLIRLLPIPHRDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGNKMDSYNLATVFAPNILRS 1031
            ||:...::|||..|.:||..|:..|.:|..:..|            |.|::.||..||.|.::|:
Zfish   377 EALHEALKLLPPAHCETLRYLMAHLKRVTQNEKD------------NLMNAENLGIVFGPTLMRA 429

  Fly  1032 THLTFSRDKEQENMIDAIN-------VVRTMINHYEEIF 1063
            ..|         :.:.|:|       ||..:|.:.:.:|
Zfish   430 PDL---------DAMTALNDIRYQRQVVELLIKNEDILF 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP102A	NP_001245416.1	RhoGAP	874..1069	CDD:295372	55/206 (27%)
chn1	NP_998165.1	SH2_a2chimerin_b2chimerin	42..128	CDD:198215	6/35 (17%)
		C1_1	206..258	CDD:278556	10/65 (15%)
		RhoGAP_chimaerin	266..459	CDD:239837	58/224 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910