Protein Alignment RhoGAP102A and Arhgap36

DIOPT Version :9

• Sequence 1: NP_001245416.1
• Gene: RhoGAP102A / 43781
• FlyBaseID: FBgn0259216
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_229133.7
• Gene: Arhgap36 / 302819
• RGDID: 1565967
• Length: 600
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 160/656 - (24%)
• Similarity: 248/656 - (37%)
• Gaps: 170/656 - (25%)

  Fly   589 KAIRTSSG------LLSSSSQFISNILHGHNNAGNQFNTLTDKLPDCNQSHATASMQKSKSLSNV 647
            ||.||...      ||.|:..|:..:|.|              .|..|...:...|....|||.:
  Rat     9 KAARTRCPRIMPLLLLLSAFIFLVCVLGG--------------APGQNPDRSRMDMVSIHSLSEL 59

  Fly   648 GQFVAKRMWRSRSKSQN-------KRSYLKSSIP----------TL-KWYPSEHFLWISESGESF 694
                      .|.|.|.       .|.:|....|          || ||:........:.|.::|
  Rat    60 ----------ERLKLQETAYHELVARHFLSEFKPDRVQPTDRPNTLQKWFQMLRGQDRAASLKTF 114

  Fly   695 QIVETNLTRLSKIESDIVKNFALEKIQELNIG-NIEDLKISPQKRR---CVPKKKSLTTSFFDNG 755
            .|         ::|..:|......|.:||... .:||:..|..:||   .|.:.......||...
  Rat   115 GI---------RLEEVLVNELTRRKQRELTDNMQVEDINGSTGRRRRGNVVQRMFGRMRRFFSRR 170

  Fly   756 KKDDQNPRSVLFGTSLECCLERDSKRNVTMEDRSKYSLLSMFRGSGSTPGSVLKLNDNVRSCESL 820
            :.:...||.          ..|..:|.....|                  ||.:|.:.....:.|
  Rat   171 RNEPTLPRE----------FTRRGRRGAISVD------------------SVAELENGALLLQIL 207

  Fly   821 PSKSLEYGSTELSAYVRGSFSNISKPLASLSQSENEDTELNFVKAYQEHSQLMVPIFVNNCIDYL 885
                              ..|.:|.|:............||.: |.|      :|..|..|..::
  Rat   208 ------------------QLSQLSLPIGQRLLGSKRKMSLNPI-AQQ------IPHIVETCCKFI 247

  Fly   886 EDNGLQQVGLFRVSTSKKRVKQLREEFDK--DIYFGISVDTCPHDVATLLKEFLRDLPEPLLCNT 948
            |.:||..||:|.:..|.:||.:|||.|||  ||....||:.  :|||.|||||.|::.:.||.:.
  Rat   248 EKHGLSSVGIFTIEYSLRRVIELRELFDKGMDIVLDDSVNV--NDVAELLKEFFREMKDSLLPDE 310

  Fly   949 LYLTFLKTQRIRNRRLQLEAISHLIRLLPIPHRDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGN 1013
            ||::||.|..::.:. |:.|:..|:.|:|..|.|||..||..|.||..:.:|....:| .|..||
  Rat   311 LYMSFLLTATLKPQD-QVSALQLLVYLMPPCHSDTLERLLKALHKVTENCEDSIGLDG-QLVPGN 373

  Fly  1014 KMDSYNLATVFAPNILRSTHLTFSRDKEQENMID----AINVVRTMINHYEEIFNISAELLNVIY 1074
            :|.|.|||.||..::|:...|.....::.:..||    ::||||.||::::.:|.:...:...:.
  Rat   374 RMTSTNLALVFGTSLLKKGKLAKRESRKTKLGIDHYVASVNVVRAMIDNWDILFQVPPHIQKQVA 438

  Fly  1075 TQALEACPEKLYELISTKVYGTEWTQQQIDDPQPGSLSDVLLEPPI------------------- 1120
            .:..::.||.| :.|..:      ..::|...:.....|.||..|:
  Rat   439 KRVWKSSPEAL-DFIRRR------NLRKIQSARIKMEEDALLSDPVDNSAEAQAAILAQSQPFDE 496

  Fly  1121 --HGKRYENINDFNNINFKRCQD-KRRDHSDPDKKK-------NNNENLEIITASLKISVAEQSH 1175
              .|....|..|..|.:|:...| :..||  ||..:       .|||:.:        |.|::..
  Rat   497 DPEGAPDVNFGDGMNYDFEDDSDFEDEDH--PDLAEVPYLDVIPNNEDTD--------SDADEMP 551

  Fly  1176 ISLKEP 1181
            .|.:||
  Rat   552 GSSEEP 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP102A	NP_001245416.1	RhoGAP	874..1069	CDD:295372	75/200 (38%)
Arhgap36	XP_229133.7	RhoGAP_ARHGAP6	228..433	CDD:239841	79/215 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340634
Domainoid	1	1.000	140	1.000	Domainoid score	I4637
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46238
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12635
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.940