DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RhoGAP102A and chin-1

DIOPT Version :9

Sequence 1:	NP_001245416.1	Gene:	RhoGAP102A / 43781	FlyBaseID:	FBgn0259216	Length:	1256	Species:	Drosophila melanogaster
Sequence 2:	NP_497323.3	Gene:	chin-1 / 175268	WormBaseID:	WBGene00015267	Length:	421	Species:	Caenorhabditis elegans

Alignment Length:	190	Identity:	55/190 - (28%)
Similarity:	89/190 - (46%)	Gaps:	19/190 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   874 VPIFVNNCIDYLEDNGLQQVGLFRVSTSKKRVKQLREEFDKDIYFGISVDTCPHDVATLLKEFLR 938
            :|..|..||..:|..||...|::|||.|...:::|:::||.:.|..::.....|.|..|||.:.|
Worm   247 LPPIVPLCIGEVESRGLDVEGIYRVSGSYDHMEKLKQQFDSNQYVDLATVCDIHTVCGLLKLYFR 311

  Fly   939 DLPEPLLCNTLYLTFLKTQRIRNRRLQLEAISHLIRLLPIPHRD----TLYVLLVFLAKVAAHSD 999
            .||:.|:..:::...|...:..|:|...|. ...||.:.:...|    ||..:|..|.|||.||
Worm   312 LLPQQLIPFSVHKQLLVAYQETNQRSTHER-ERQIRKVMMELSDANIITLGAVLAHLKKVADHS- 374

  Fly  1000 DIWSTEGCCLTLGNKMDSYNLATVFAPNILRSTHLTFSRDKEQENMIDAINVVRTMINHY 1059
                       ..|||...||||:|:|.:..|..:....:.:..:.:  ||..|.:..|:
Worm   375 -----------AKNKMTVENLATIFSPTLFCSGSIPAMPNHQLLHFL--INNPRVVPKHH 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP102A	NP_001245416.1	RhoGAP	874..1069	CDD:295372	55/190 (29%)
chin-1	NP_497323.3	SH2_a2chimerin_b2chimerin	43..130	CDD:198215
		C1_1	172..224	CDD:278556
		RhoGAP	248..413	CDD:238090	52/179 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870