Protein Alignment RhoGAP102A and arhgap6

DIOPT Version :9

• Sequence 1: NP_001245416.1
• Gene: RhoGAP102A / 43781
• FlyBaseID: FBgn0259216
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_017210032.1
• Gene: arhgap6 / 101882360
• -ID: -
• Length: 635
• Species: Danio rerio
• Alignment Length: 661
• Identity: 163/661 - (24%)
• Similarity: 261/661 - (39%)
• Gaps: 168/661 - (25%)

  Fly   712 VKNFALEKIQELNIGNIEDLKISPQKRRC----------VPK-----KKSLTTSFFDNGK-KDDQ 760
            :::.:::.:.||....::::.::   |.|          :||     ||||........| |.|:
Zfish     1 MQSVSIQSLSELERVRLQEVSLA---RLCKDFDLGCQITIPKDGQKRKKSLRRKLDSLSKEKRDK 62

  Fly   761 NPRSVLFGTSLECCLERDSKRNVTMEDRSKYSLLSMFRGSGSTPGSVLKLNDNVR---------S 816
            ......||..|...:..|.::....|:|.:       |||     |.|.|:.:.|         |
Zfish    63 ESEPQAFGVPLSQVIFNDRRQKQQQEEREQ-------RGS-----SPLHLHTHTRRNTSRDLSSS 115

  Fly   817 CESLPSKSLEY---------GSTELSAYVRGSFS------------------NISKPLASLSQSE 854
            ..||.|.|..:         ..|.|.:..||..|                  .:|.|:...|:.:
Zfish   116 NSSLSSSSETHTDNNNTPQTPETALRSRRRGGVSVDCITDLDDSDSRLLEALQLSMPVDPSSEKK 180

  Fly   855 NEDTELNFVKAYQEHSQLMVPIFVNNCIDYLEDNGLQQVGLFRVSTSKKRVKQLREEFDKDIYFG 919
            .:..:.:..|.........||..::.|..:|:..|||.||:|||.:|||||:||||.||:.....
Zfish   181 KKKKKTSGEKLSLNPIYRQVPRVLDCCCQHLQRYGLQTVGIFRVGSSKKRVRQLREAFDQGAEVI 245

  Fly   920 ISVDTCPHDVATLLKEFLRDLPEPLLCNTLYLTFLKTQRI----RNRRLQLEAISHLIRLLPIPH 980
            :......||||.||||||||:|:|||...||..|:....:    ::|.:||     |:.|||..:
Zfish   246 LDDRHSVHDVAALLKEFLRDMPDPLLTRELYAAFISCASLEKSEQHRIIQL-----LLCLLPACN 305

  Fly   981 RDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGNKMDSYNLATVFAPNILRSTHLTFSRDKE---- 1041
            .|||..||.||:.||.|:::.....| ...:||||.|.||||:|.||:|   |...|.:||
Zfish   306 SDTLQCLLHFLSTVAKHAENSCDEHG-NQVMGNKMTSLNLATIFGPNLL---HKQKSSEKEFSVQ 366

  Fly  1042 ----QENMIDAINVVRTMINHYEEIFNISAELLNVIYTQALEACPEKLYELISTKVYGTEWTQQQ 1102
                .|.....|:||:.||:.:..:|.|||||.|.:....|:...:.:..|:..|....|.:...
Zfish   367 SSVRMEESAAIISVVQYMIDKHHTLFMISAELQNEVLLSLLDTDSDVVDYLMRRKTPQCEDSVCS 431

  Fly  1103 IDDPQPGSLSDVLLEPPIH------GKRYENINDFNNINFKRCQDKRRDHSDPDKKKNNNENL-- 1159
            ..:..|...:..:|....|      ...:.:::..:.:||  |..  ..|:|..:..::..::
Zfish   432 SGEVSPYDNNSPVLSEWFHPSGSSLANTHHHLSSNSAVNF--CLS--ATHTDSGESLHDEAHVWR 492

  Fly  1160 -----------EIITAS-------------------LKISVAEQSHISLKEPIKEQEPITSYKQF 1194
                       :::|.|                   .|..:...:|.:...||.|:.. |:..|.
Zfish   493 TRHTLLTGLHDKLLTGSDGNLYKRASSDVFYDDDRDAKPEMQTSNHQTPHRPITERNK-TALSQS 556

  Fly  1195 SRSTLPTSISDVGVNTLRTDGAKLENKMKILTSNINKQDIPIKTTYKRQNLIS------------ 1247
            ..:..|.|                       .|..:|||..:......|.|::
Zfish   557 EEAEAPVS-----------------------QSASSKQDDRLPAAASMQPLVNSCHGAQGSSSHI 598

  Fly  1248 --SSRRISQEP 1256
              ||:.:.|.|
Zfish   599 TVSSKSLDQHP 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP102A	NP_001245416.1	RhoGAP	874..1069	CDD:295372	87/206 (42%)
arhgap6	XP_017210032.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580440
Domainoid	1	1.000	122	1.000	Domainoid score	I5601
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006356
OrthoInspector	1	1.000	-	-		otm24611
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12635
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6395
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.030