Protein Alignment RhoGAP102A and Arhgap6

DIOPT Version :9

• Sequence 1: NP_001245416.1
• Gene: RhoGAP102A / 43781
• FlyBaseID: FBgn0259216
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_017457773.1
• Gene: Arhgap6 / 100363276
• RGDID: 2323364
• Length: 985
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 200/663 - (30%)
• Similarity: 298/663 - (44%)
• Gaps: 109/663 - (16%)

  Fly   487 GVLNPPGISAGLHKAVQTLNAWPLI---------ALDFIRGNE-SSLNLKNAHLEWL--RLEDER 539
            |..:..|.|.  .|..||.:..|.:         |.|.:||:. |.||......|.|  ||....
  Rat    20 GTASTKGFSK--RKLRQTRSLDPALISGCGSEMGAEDGLRGSTVSRLNSPQLSAESLGSRLASSP 82

  Fly   540 SHMQLERDKNPIELRSKVNPLQIASPANTSSYSKCTSAPTSPTSHSKLEKAIRTS-SGLLSSSSQ 603
            ....|...:.|.       |..:.|..:|.|    |....||:.....:..:..| |||..|.:.
  Rat    83 RSQHLRATRFPA-------PRPLCSSFSTPS----TPQEKSPSGSFHFDYEVPLSRSGLKKSMAW 136

  Fly   604 FISNILHGHNNAGNQFNTLTDKLPDCNQSHATASMQKSKSLSNVGQFVAKRMWRSRSKSQ---NK 665
            .:.::|.|..:..|                 .||:..|......|.|.:.|.|..:.|.|   |.
  Rat   137 DLPSVLTGSVSGRN-----------------PASILGSSGGGPNGIFASPRRWLQQRKFQPPPNS 184

  Fly   666 RSYLKSSIPTLKWYPSEHFLWISESGESFQIVETNLTRLSKIESDIVKNFALEKI-QELNIGNIE 729
            ||:     |.:.|.....|.|.|.||.|.::....:..||::|...::..|..:: |:.::|...
  Rat   185 RSH-----PYVVWRSEGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQLQQDCDLGCQI 244

  Fly   730 DLKISPQKRRCVPKKKSLTTSFFDNGKKDDQNPRSV--LFGTSLECCLERDS----KRNVTME-- 786
            .:....|||     ||||.......||:.:::...:  .||..|...:..|.    |:::..|
  Rat   245 TIPKDGQKR-----KKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRAYKLKQDLQREEQ 304

  Fly   787 -DRSKY--SLLSMFRGSGSTPGSVLKLNDNVRSCESLPSKSLEYGSTELS--AYVRGSFS----- 841
             |.|.:  |||..  |:......:...|.::.|....|::|....:.|.:  |..||:.|
  Rat   305 KDASDFVSSLLPF--GNKKQNKELSSSNSSLSSTSETPNESTSPNTPEPAPRARRRGAMSVDSIT 367

  Fly   842 ----NISKPLASL-----SQSENE-----DTELNFVKAYQEHSQLMVPIFVNNCIDYLEDNGLQQ 892
                |.|:.|.:|     ::::|:     |.:|:....|::     ||..|::|..:||.:|||.
  Rat   368 DLDDNQSRLLEALQLSLPAEAQNKKQKARDKKLSLNPIYRQ-----VPRLVDSCCQHLEKHGLQT 427

  Fly   893 VGLFRVSTSKKRVKQLREEFDKDIYFGISVDTCPHDVATLLKEFLRDLPEPLLCNTLYLTFLKTQ 957
            ||:|||.:|||||:|||||||:.:...:..:...||||.||||||||:|:|||...||..|:.|.
  Rat   428 VGIFRVGSSKKRVRQLREEFDRGVDVCLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTL 492

  Fly   958 RIRNRRLQLEAISHLIRLLPIPHRDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGNKMDSYNLAT 1022
            .:.... ||..:..||.|||..:.|||:.||.||:.||.|::|..|.:|..:| ||||.|.||||
  Rat   493 LLEPEE-QLGTLQLLIYLLPPCNCDTLHRLLQFLSIVARHAEDNVSKDGQEVT-GNKMTSLNLAT 555

  Fly  1023 VFAPNILRSTHLTFSRDKE--------QENMIDAINVVRTMINHYEEIFNISAELLNVIYTQALE 1079
            :|.||:|   |...|.|||        .|.....|.||:.||.:||.:|.:..:|.|.:....||
  Rat   556 IFGPNLL---HKQKSSDKEYSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLE 617

  Fly  1080 ACPEKLYELISTK 1092
            ..|:.:..|:..|
  Rat   618 TDPDVVDYLLRRK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP102A	NP_001245416.1	RhoGAP	874..1069	CDD:295372	94/202 (47%)
Arhgap6	XP_017457773.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340635
Domainoid	1	1.000	140	1.000	Domainoid score	I4637
eggNOG	1	0.900	-	-		E1_KOG2710
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006356
OrthoInspector	1	1.000	-	-		otm46238
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12635
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6395
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930