Protein Alignment RhoGAP102A and LOC100005008

DIOPT Version :9

• Sequence 1: NP_001245416.1
• Gene: RhoGAP102A / 43781
• FlyBaseID: FBgn0259216
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_001344168.4
• Gene: LOC100005008 / 100005008
• -ID: -
• Length: 958
• Species: Danio rerio
• Alignment Length: 1075
• Identity: 203/1075 - (18%)
• Similarity: 360/1075 - (33%)
• Gaps: 359/1075 - (33%)

  Fly   216 AQRPNFKNNGD----------NHQVISSGTSIQTELLSLLKLLSNCPLFTHEGIQLKFGDAPLSI 270
            ||:|:.:.|||          |.|:.:..|.||.|        ::....:|:..........|.:
Zfish    26 AQQPSIERNGDAPLPPPDVQINTQMKTQETDIQHE--------ASVDGSSHQSTSASVPPDLLDV 82

  Fly   271 LEDKVLL----KKIYSALKKQQLHRTLHSKDPYQANFSTSLSCLIKNGKELSRGN---------- 321
            ...:.|:    ..|.|.|..:.| |:..|.|...|:.|.      |..:.||:|.
Zfish    83 KSSETLVWPSSISISSGLSVEAL-RSADSDDSPAASDSP------KTHQHLSKGQHNVQKASKTD 140

  Fly   322 --TDSNRSNKLLHDNFFCLMKCDTKPIIP--------------------SPKTEF------FLDL 358
              ||...:|:.:|.....|.|...:|..|                    ..::||      :||:
Zfish   141 KLTDVQWANEEIHLQSESLQKMPDRPKKPRAATIRVSRKKQTLSGQKSDQTRSEFTVSQSSWLDV 205

  Fly   359 NKVPQNFELKNKLNSNGQSVERIQKTCGTQTNFI-QLSELKTLAEQ-------------YNLMVT 409
            .|..::..|...|:.|..|:.:  |.....|.:: .::.:..:::|             :..|..
Zfish   206 WKGRKHMVLWATLDGNLMSMWK--KRTDKFTEYVFHVASVTNISKQEHGRFSIHLQKKHFEFMAH 268

  Fly   410 NC---DNTLKLLEE---------PSK------QDCSKS------SHLIFRRSSLDEDIS-----Q 445
            |.   |..|..|.:         |.|      :|..|.      .|.::..|| .||.:     .
Zfish   269 NAAVQDGWLHSLYDSRGREAIAAPKKHGPLSMKDRRKKVYSAICGHSLWIYSS-KEDFNLGLGMM 332

  Fly   446 SVSDTIKRYLNMARKKSMQ---------------DSDSNR-----FKSINYDKNLRNIKAK---- 486
            .||      :|:|..||..               .:||::     .:|:|  ..:||..:.
Zfish   333 CVS------MNIASVKSTGRYGFSLITPYRTFNFSADSSKEASAWLESLN--DVIRNALSYSEVA 389

  Fly   487 ---------------GVLNPPGIS-----------AGLHKAVQTLNA-----------W--PLIA 512
                           |..||...|           ||.|:::.:..:           |  |||.
Zfish   390 LRLWSSPCNKVCADCGAANPEWASVNLLVVICEACAGAHRSMGSSRSKVRGLKLDDKVWTEPLIQ 454

  Fly   513 LDFIRGNESSLNL------KNAHLEWLRLEDERS-------HMQLERDKNPIELRSKVNPLQ--- 561
            |..:.||:::.|:      ....:..|...|:|:       |..|.|..:|:....|:...:
Zfish   455 LFVLHGNKTANNVWGHNIPPTEQISPLASPDQRAEFILAKYHKGLYRKAHPLAASQKLLDQRLRE 519

  Fly   562 -IASPANTSSYS-KCTSAPTS-PTSHSKLEKAIRTSSGLLSSSSQFISNILHGHNNAGNQFNTLT 623
             :..||...:.| .|:.|..| .:|..:|:.||    .:..|:.|.:...|..|    |:|
Zfish   520 VVCGPAVEETVSLLCSGAKVSCSSSDPELKSAI----AVAESAGQALQTELLRH----NEF---- 572

  Fly   624 DKLPDCNQS-HATASMQKSKSLSNVGQFVAKRMWRSRSKSQNKRSYLKSSIPTLKWYPSEHFLWI 687
            .:.||..|: |:...|::                            |...:      ..|.||:.
Zfish   573 VEAPDFEQTRHSEEQMEE----------------------------LHGKL------DEERFLFS 603

  Fly   688 SES-GESFQIVETNLTRLSKIESDIVKNFALE--KIQELNIGNIED-LKISPQKRRCVPKKKS-- 746
            .|: ..::.:::.         :::|..|...  :..:..:..:.| |..|..:|..:....:
Zfish   604 QENQSAAYDVLDL---------TEVVSVFDCSDGETHQFEVSTLTDRLTCSADERNALLSHMTHI 659

  Fly   747 LTTSFFDNGKKDD------QNPRSVLFGTSLE-----CCLERDSKRNVTMEDRSKYSLLSMFRGS 800
            :.....|..|:||      .:..|:..|.:|:     |.|:.......|::.||:.:|:
Zfish   660 MKVVLADTVKQDDLLGVFAVSKLSIREGAALQFAEVWCSLQEGEMSVHTLQLRSRETLI------ 718

  Fly   801 GSTPGSVLKLNDNVRSCESLPSKS---LEYGST------ELSAYVRGSFSNISKPLASLSQSENE 856
                     ||...| |....|::   ||:...      ||....|.....:.|.::|.:..:..
Zfish   719 ---------LNAQTR-CYLQSSENCILLEFPDRTFHMQFELEHSCRRWHELLQKAMSSSTDGQQR 773

  Fly   857 DTELNFVKAYQEHSQLMVPIFVNNCIDYLEDNGLQQVGLFR-----------VSTSKKRVKQLRE 910
            ...              ||..|:.||.::..:||...||:|           |.|.:...|:...
Zfish   774 AGS--------------VPTSVHRCISHITLHGLMVEGLYRRCGIAPQISKLVDTLRVSPKEAVL 824

  Fly   911 EFDKDIYFGISVDTCPHDVATLLKEFLRDLPEPLLCNTLYLTFLKTQRIRNRRLQLEAISHLIRL 975
            :.|:     :||    .||:..||:.||.  ..|:..|....:.....:...:::|:....|::.
Zfish   825 QTDE-----LSV----LDVSGALKQILRQ--SELIPQTHRPHWQNAAALPGEKVRLQTYRELLKQ 878

  Fly   976 LPIPHRDTLYVLLVFLAKVAAHSDDIWSTEGCCLTLGNKMDSYNLATVFAPNILRSTHLTFSRDK 1040
            ||..:..||..|...|..|..||..            |:|.::|||.:|.....:...:.
Zfish   879 LPPDNIATLSALCAHLNNVQKHSQT------------NRMTAHNLAVIFVVIFFQELAMN----- 926

  Fly  1041 EQENMIDAINVVRTMINHYEEIFNISAELLNVIYT 1075
                 |:.:.:.|.:|.::..||....|....|.|
Zfish   927 -----INMVQMTRELILNHTHIFRSPVETDGAIVT 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP102A	NP_001245416.1	RhoGAP	874..1069	CDD:295372	46/205 (22%)
LOC100005008	XP_001344168.4	PH-like	291..375	CDD:302622	17/90 (19%)
		PH	292..380	CDD:278594	19/96 (20%)
		ArfGap	386..503	CDD:279720	21/116 (18%)
		RhoGAP	769..939	CDD:295372	44/216 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	1	0.960