Protein Alignment CG1674 and Synpo2

DIOPT Version :10

• Sequence 1: NP_001245414.1
• Gene: CG1674 / 43780
• FlyBaseID: FBgn0039897
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: NP_536699.2
• Gene: Synpo2 / 118449
• MGIID: 2153070
• Length: 1257
• Species: Mus musculus
• Alignment Length: 33
• Identity: 12/33 - (36%)
• Similarity: 13/33 - (39%)
• Gaps: 1/33 - (3%)

  Fly   119 YALYYRGDYFCSFGINFLTKDPDS-RRKSYVSG 150
            |..||.|..:...|...|.....| ||..|.||
Mouse     4 YGSYYGGLGYGYGGFGGLNCGCSSIRRLGYGSG 36

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1674	NP_001245414.1	None
Synpo2	NP_536699.2	PDZ_SYNPO2-like	8..85	CDD:467264	10/29 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..52		6/13 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	88..112
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	207..272
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	320..359
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:16309678	388..396
		Interaction with YWHAB. /evidence=ECO:0000269|PubMed:15883195	551..557
		PHA03247	<571..1104	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	581..817
		Interaction with YWHAB. /evidence=ECO:0000269|PubMed:15883195	599..804
		PPPY motif. /evidence=ECO:0000250|UniProtKB:Q9UMS6	611..614
		Interaction with ACTN2. /evidence=ECO:0000250|UniProtKB:Q9UMS6	656..917
		F-actin bundling activity. /evidence=ECO:0000250|UniProtKB:Q9UMS6	656..909
		F-actin binding. /evidence=ECO:0000250|UniProtKB:Q9UMS6	656..796
		Actin binding. /evidence=ECO:0000269|PubMed:11673475	740..893
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	832..863
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	930..952
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	970..1012
		Interaction with ZYX. /evidence=ECO:0000250|UniProtKB:Q9UMS6	993..1012
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1037..1060