Protein Alignment CG1674 and Synpo

DIOPT Version :9

• Sequence 1: NP_001245414.1
• Gene: CG1674 / 43780
• FlyBaseID: FBgn0039897
• Length: 905
• Species: Drosophila melanogaster
• Sequence 2: XP_006525531.1
• Gene: Synpo / 104027
• MGIID: 1099446
• Length: 1140
• Species: Mus musculus
• Alignment Length: 1088
• Identity: 198/1088 - (18%)
• Similarity: 336/1088 - (30%)
• Gaps: 371/1088 - (34%)

  Fly    44 APDLKMENTKNSIP-SPI--KPNVNDQTSSASDLTAENTKADHDSLNKP-KDFNNQILNIISDID 104
            :|.|..|..:...| |||  .|..:.:.:|.|    :.....|.|...| :.....|:...|:..
Mouse   187 SPKLNQEALQTGRPLSPIGHAPGPSVKPTSPS----KPGSPKHPSPQSPSRGVAGHIMEGYSEEA 247

  Fly   105 INIKAQEKITQLKEQELKLI--QKQND---LANEIHKQQILAKQLSAQNQLKQNECQSGELDL-- 162
            ..::..||:.. :|:|:.|:  .|:|.   .||.:|..|....|.|:.|. ...|..|...|:
Mouse   248 SLLRHLEKVAS-EEEEVPLVVYLKENAALLTANGLHLSQSRETQQSSPNP-PDTEVPSPAADINQ 310

  Fly   163 -----------------HSQYQNERGGPTSTLYQEKNIASKQIPVVHNNMNC----TVEKKRG-- 204
                             |||       ||:.:.|....|...:|...:...|    |::.|.|
Mouse   311 NPSSPNATLTTLASSSHHSQ-------PTADINQNPPAAITPVPQNSSQAQCSPNGTLDSKPGTL 368

  Fly   205 -----------------------------------------------------------YRPSDL 210
                                                                       .:||.|
Mouse   369 CADDGQSPVPAEEVRSSILLIDKVSAPPSAASTFSREATPLSSSGPPAADLMSSSLLIDMQPSTL 433

  Fly   211 IDPSKRQ----YLLSLSKKLWQE-----KKESANVSKTVDLRKIFTPATDAAEILP-KNRKLYAS 265
            :.|::::    ..::...|::.|     .|.::.|::|.....|.:|.|...|..| ..|:.:..
Mouse   434 VAPAEQEVPGHVAVTTPTKVYSEVHLTLAKPASVVNRTARPFGIQSPGTSQIEQSPMMGRRQFGE 498

  Fly   266 SAFYSPTLHPTVEDQVELARRISHSLSDISNQTSK---GQSMYVNRK---KRSDKWVHEGGSQGN 324
            .|:..|                :.|::|.|.|..:   .:|..|.|:   :||.  |.|....||
Mouse   499 KAWAPP----------------ASSMADRSPQPQRHIMSRSPMVERRLLGQRSP--VLERRPLGN 545

  Fly   325 DAINPFKENSETKSTMEVA-KLEKIPLKLIMNPNGKVRDYNSLKDLINVEAGLLSPDNCAELITA 388
              ..|....:||.||..|| ::...|....:.|:...:. :.||       |.::|.|...::..
Mouse   546 --FTPPPTYAETLSTAPVASRVRSPPSYSTLYPSSDPKP-SHLK-------GQVAPANKTGILEE 600

  Fly   389 LQLHQGRGAELFA----------------------KRRRKADNWVVDESHSGTQYHPSGI-PDFQ 430
            ....:|....:|.                      |||::      |....|.:..|..: .:..
Mouse   601 SMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQR------DHGEVGMEEEPFALGAEAS 659

  Fly   431 QYQQRPVLSPNILPA-----------------------------YSDAGKHRVQLNIHQNQLIEK 466
            .:||.|:......||                             .|:|.....:|...:...:||
Mouse   660 NFQQEPIARDRASPAAAEEAVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEK 724

  Fly   467 Y---SKPGLQVVQSP---------WKAALQTGSASSAFLEDTKS--FSPPA------------LT 505
            |   |....::.:.|         ||   .|.:|...|...:.|  .:|||            |.
Mouse   725 YVIESSGHAELARCPSPTMSLPSSWK---YTTNAPGGFRVASLSPARTPPASLYHGYLPENGVLR 786

  Fly   506 PIPSSQAGSK------DWTDANEPMPHGSSRRNTNAVAS---SPRSV---------IVPSNPQRD 552
            |.|:.|...:      ..:...|| ...|||..::...|   |||:.         :||:.|:..
Mouse   787 PEPTKQQPYQMRPSLYALSPVKEP-AKASSRATSSRTPSRTVSPRAASPAKPSSLDLVPNLPRAG 850

  Fly   553 LAYTPCV---AQGWGGRSVELPKDSFQSNESQSSWQTE-----------PHIGRADDSNPSFNNY 603
            |..:|.:   ::...|......:||.|......::.::           |...:|  ..|||:
Mouse   851 LPPSPALPRPSRSSPGLYTAPVQDSLQPTAVSPTYSSDISPVSPSRAWSPRAKQA--PRPSFS-- 911

  Fly   604 IFGERLTSNFAFDVQNRLHSLENFQKYFLEYQRLELEILRNRESSRVLQHDAYESLLDFTPQNEF 668
                  |.|...:.|:|..||.....:.....|....:            |.:.|...:.|....
Mouse   912 ------TRNAGIEAQDRPESLPTSPPWTPAASRPPSSL------------DGWVSPGPWEPGRGS 958

  Fly   669 KVISGEDLKVNCDLDEKVNVRELIQSFEKQNTTDLRHDAAPIEGLYVPKEISLSSYAAPSQQCEI 733
            .:.|...|.....:....:.|.:   ...::.|:.|..:..::.|.....|:.:...:.|
Mouse   959 SMSSPPPLPPPPPMSPSWSERSV---SPLRSETEARPPSRQLQALLARNIINAARRKSAS----- 1015

  Fly   734 HSKHFERPYEDTFPRTFPRNNYSANNNFPGNDGIGEFPLSKPTGLTTGTLHQQPYSPTSYKKTVP 798
                         ||..|.....              |.|.|.|         |..|.:..::..
Mouse  1016 -------------PRPAPAETLR--------------PFSPPQG---------PPPPPARMRSPQ 1044

  Fly   799 GLEKVENF--ARYEQPDRKRLTSGSPQYLNALQNSQVRNASPIPF-------GTSLNEQTSWPPR 854
            ......||  |.:....|..|..| |....:.::.|...:.|.|:       ..||:.:.|
Mouse  1045 PASPARNFRGAAFSPIPRSPLPIG-PSSCASPRSPQAAPSRPFPYRRSPTDSDVSLDSEDS---- 1104

  Fly   855 SVLLQGGSPSPLPNHVQTFNKCAKGW-GSIPVKQQSYSSQYNLPGNLP 901
                  |..||   .:..:|.|.:|| ||:.:|:          |:||
Mouse  1105 ------GLKSP---GILGYNICPRGWNGSLRLKR----------GSLP 1133

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1674	NP_001245414.1	None
Synpo	XP_006525531.1	PTZ00449	<51..367	CDD:185628	43/192 (22%)
		PRK13914	<254..>371	CDD:237555	29/125 (23%)
		PHA03247	<291..583	CDD:223021	56/320 (18%)
		PHA03247	<815..1087	CDD:223021	56/338 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838014
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24217
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030