DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment yellow-h and RGN

DIOPT Version :9

Sequence 1:NP_651912.3 Gene:yellow-h / 43779 FlyBaseID:FBgn0039896 Length:463 Species:Drosophila melanogaster
Sequence 2:NP_004674.1 Gene:RGN / 9104 HGNCID:9989 Length:299 Species:Homo sapiens


Alignment Length:222 Identity:42/222 - (18%)
Similarity:73/222 - (32%) Gaps:63/222 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 VPKN----NLPLGIDVHNNRLFVTTP-----RWKNGVPASLGTLPFPPKESSPAIKPYPNWEAHG 137
            :|:|    ..|:..:|.|:.|||..|     || :.....:..:......||.|::....:    
Human    10 LPENCRCGESPVWEEVSNSLLFVDIPAKKVCRW-DSFTKQVQRVTMDAPVSSVALRQSGGY---- 69

  Fly   138 NPNNPDCSKLMSVYRTAVDRCDRIWLIDSGIVNATI---------NLNQICP------------- 180
                        |.......|...|...|.:|.||:         |..::.|             
Human    70 ------------VATIGTKFCALNWKEQSAVVLATVDNDKKNNRFNDGKVDPAGRYFAGTMAEET 122

  Fly   181 -PKIV------VYDLKSDELIVRY--NLEASHVKQDSLHSNIVVDIGEDCDDAHAIVSDVWRFGL 236
             |.::      :|.|..|..:.:|  .::.|:....||...|...|     |:.:...|.:.:.|
Human   123 APAVLERHQGALYSLFPDHHVKKYFDQVDISNGLDWSLDHKIFYYI-----DSLSYSVDAFDYDL 182

  Fly   237 LVYSLSKNRS-WRVTNYNFYPDPFASD 262
            ....:|..|| :::......||....|
Human   183 QTGQISNRRSVYKLEKEEQIPDGMCID 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
yellow-hNP_651912.3 MRJP 148..440 CDD:281074 28/147 (19%)
RGNNP_004674.1 SGL 16..264 CDD:400653 40/216 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG3386
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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