Protein Alignment CG31999 and Fbn2

DIOPT Version :9

• Sequence 1: NP_001284712.1
• Gene: CG31999 / 43777
• FlyBaseID: FBgn0051999
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_114014.2
• Gene: Fbn2 / 689008
• RGDID: 620910
• Length: 2907
• Species: Rattus norvegicus
• Alignment Length: 1163
• Identity: 305/1163 - (26%)
• Similarity: 391/1163 - (33%)
• Gaps: 439/1163 - (37%)

  Fly     6 CAFMCFLIVGGHVTTTMASDSISGYIRKCCINGLRHARTTASCKKIDIAPTIIPQLWLGLCHST- 69
            |:|....:.|       ..:::.|.....|.:|....||..:|..||.....| ....|||.:|
  Rat  1488 CSFQNICVFG-------TCNNLPGMFHCICDDGYELDRTGGNCTDIDECADPI-NCVNGLCVNTP 1544

  Fly    70 --LEVCCSRELDHQ---------DCELGRLAALDGTRCDGEGNVTSS-----SYATCCRSCQIGL 118
              .|  |:...|.|         |..:|......|.|.||..:..:.     |.::||  |.:|.
  Rat  1545 GRYE--CNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEVGVGVSRSSCC--CSLGK 1605

  Fly   119 AVKASKANCKDPLFSFIFLIESYRACCYGSADFKDQP------GIDEIDKANSITDEG------- 170
            |.......| .|:.|     ..|...|.|...|:..|      .|||..:...:...|
  Rat  1606 AWGNPCETC-PPVNS-----TEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNCINTFG 1664

  Fly   171 ----ELP---FVSEEDMNVTIVLTGDDDICGKIENLCAH-------ICENTFDAYQCKCHPGFML 221
                |.|   ::|||..           ||..|:...||       .|.||...|.|.|.|.:|.
  Rat  1665 SFQCECPQGYYLSEETR-----------ICEDIDECFAHPGVCGPGTCYNTLGNYTCICPPEYMQ 1718

  Fly   222 DNNNVTCSPMKTQICPSGYNLDKLDN--------------------------------------- 247
            .|....|..|:...|...||....:|
  Rat  1719 VNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGKAWNKPCEPCPTPGTADFKTI 1783

  Fly   248 --------------KCIDIDECREDLHDCKSSQYCHNTNGGYHCLNVKEKECPPGFHYD------ 292
                          |.:|||||:|....| ::..|.|..|.:.|      |||.||.|:
  Rat  1784 CGNIPGFTFDIHTGKAVDIDECKEIPGIC-ANGVCINQIGSFRC------ECPTGFSYNDLLLVC 1841

  Fly   293 HDYDACKD----------------DYKCK--------------DRK-------------CVKIQS 314
            .|.|.|.:                .|:|:              ||.             ||.:|.
  Rat  1842 EDIDECSNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQG 1906

  Fly   315 -----CDKGF--SLHNGTCSDIDECSHKSLNNCHVNSNQECVNTVGSYSCNCLPGFNLDATLNKC 372
                 |:.||  |.....|.|:|||..      |...|..|.||||||:|.|.|||.|... |.|
  Rat  1907 SYQCICNNGFKASQDQTMCMDVDECER------HPCGNGTCKNTVGSYNCLCYPGFELTHN-NDC 1964

  Fly   373 VDINECSINNHNCLPTQRCDNTIGSYICTRLQSCGTGYTLNAETGNCDDDDECTLSTHNCPSNYD 437
            :||:|||..........||.|.|||:.|.    |..||.|..:..||.|.:||.....:| |...
  Rat  1965 LDIDECSSFFGQVCRNGRCFNEIGSFKCL----CNEGYELTPDGKNCIDTNECVALPGSC-SPGT 2024

  Fly   438 CHNTRGSFRC-----YRKIS--------------TMLTTRTTST------TVPP---LSLENARR 474
            |.|..|||||     |...|              ..|....|:|      ..||   || :|.||
  Rat  2025 CQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGSCTNTPGGFQCICPPGFVLS-DNGRR 2088

  Fly   475 SFTSRY------------------------------------------------------PY--- 482
            .|.:|.                                                      ||
  Rat  2089 CFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDEVAFQDLCPYGHG 2153

  Fly   483 --PLAVH------------PEYSQNNDSISTNR--RVDCSPGFYRNTLGA-CIDTNECMEQNPCG 530
              | ::|            |....|...|:|:.  |.:|..|:..:..|. |:||:||...||||
  Rat  2154 TVP-SLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYSGVRCVDTDECSIGNPCG 2217

  Fly   531 NHE---------------------------------------RCINTNGHFRCESLLQCSPGYKS 556
            |..                                       ||:||.|.:.|    .|..||..
  Rat  2218 NGTCANVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYEC----TCPVGYAL 2278

  Fly   557 TVDGKSCIDIDECDTGEHNCGER-QICRNRNGGFVCSCPIGHELKRSIGGASTCVDTNECALEQR 620
            ..|.|.|.|:|||..|.|:|..| .:|:|..|.|:|.||.|  :.|...|.. |||.|||..:..
  Rat  2279 REDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPG--MARRPDGEG-CVDENECRTKPG 2340

  Fly   621 VCPLNAQCFNTIGAYYCECKAGFQKKSDG-----NNSTQCF------------------------ 656
            :|. |.:|.|.||:|.|||..|||..|.|     |....||
  Rat  2341 ICE-NGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQGLCFAEVLQTMCQMASSSRNLVTKSECC 2404

  Fly   657 -------------------------------------DIDECQVIPGLCQQ-KCLNFWGGYRCTC 683
                                                 |||||:|:|.||.. :|:|..|.:||.|
  Rat  2405 CDGGRGWGHQCELCPLPGTAQYKKICPHGPGYATDGRDIDECKVMPSLCTNGQCVNTMGSFRCFC 2469

  Fly   684 NSGYQLGPDNRTCNDINECEVHKDYKLCMGLCINTPGSYQCSCPRGYILAADMNTCRDVDECATD 748
            ..||........|.|::||.  :..|.|..:|.||.|||||||||||:|..|..||:|:|||.|.
  Rat  2470 KVGYTTDISGTACVDLDECS--QSPKPCNFICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTK 2532

  Fly   749 SINQVCTGRNDICTNIRGSYKCTTVNCPLGYSIDPEQKNRCRQNLNFCEGEECYTQPS 806
            ..|  |   ..:|.|..|.:.|   .||.|::   :....|..|      .||.:|||
  Rat  2533 QHN--C---QFLCVNTLGGFTC---KCPPGFT---QHHTACIDN------NECGSQPS 2573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_001284712.1	vWFA	<189..227	CDD:294047	14/44 (32%)
		EGF_CA	251..293	CDD:238011	17/47 (36%)
		EGF_CA	328..>363	CDD:214542	16/34 (47%)
		EGF_CA	519..564	CDD:214542	20/83 (24%)
		EGF_CA	565..601	CDD:238011	16/36 (44%)
		EGF_CA	611..651	CDD:284955	19/44 (43%)
		vWFA	<655..695	CDD:294047	19/101 (19%)
		cEGF	678..701	CDD:289433	7/22 (32%)
		EGF_CA	698..>730	CDD:214542	17/31 (55%)
		cEGF	721..744	CDD:289433	15/22 (68%)
Fbn2	NP_114014.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910