Protein Alignment CG31999 and efemp2b

DIOPT Version :9

• Sequence 1: NP_001284712.1
• Gene: CG31999 / 43777
• FlyBaseID: FBgn0051999
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001153830.1
• Gene: efemp2b / 572703
• ZFINID: ZDB-GENE-030219-125
• Length: 440
• Species: Danio rerio
• Alignment Length: 555
• Identity: 160/555 - (28%)
• Similarity: 229/555 - (41%)
• Gaps: 152/555 - (27%)

  Fly   386 LPTQRCDNTIGSYICTRLQSCGTGYTLNAETGNCDDDDECTLSTHNCPSNYDCHNTRGSFRCYRK 450
            ||...|.:...|...|   .|..||..:.:|..|.|.:||......|.....|.|..|.:.|..:
Zfish    15 LPGTICQSPAESEAYT---DCTDGYEWDEQTQLCRDINECETILEACRGEMKCFNHYGGYLCLPR 76

  Fly   451 ISTMLTTRTTSTTVPPLSLENARRSFTSRYPYPLAVHPEYSQNNDSISTNRRVDCSPGFYRNTLG 515
            .|.::|...|::...|            ..|.|:   ||
Zfish    77 SSYVITAPETASQSEP------------NVPVPV---PE-------------------------- 100

  Fly   516 ACIDTNECMEQNPCGNHERCINTNGHFRCESLLQCSP-GYKSTVDGKSCIDIDECDTGEHNCGER 579
                 ||..  |||                      | ||::  .|:||:|||||:...|:|...
Zfish   101 -----NEAF--NPC----------------------PLGYRA--QGESCVDIDECELNMHDCQPS 134

  Fly   580 QICRNRNGGFVCSCPIGHELKRSIGGASTCVDTNECALEQRVCPLNAQCFNTIGAYYCECKAGFQ 644
            |.|.|..|.|.|.||.|:.   .||  ..|||.:||  ..|.|  ..:|.|..|::.|||:.|||
Zfish   135 QECINTVGTFTCQCPDGYS---KIG--IECVDIDEC--RYRYC--QHRCVNVPGSFSCECEPGFQ 190

  Fly   645 KKSDGNNSTQCFDIDECQV-IPGLCQQKCLNFWGGYRCTCNSGYQLGPDNRTCNDINECEVHKDY 708
            ..  |||.: |.|::||:: .|  |||:|.|.:|.:.|.|:.||.||||..:|||||||    .|
Zfish   191 LA--GNNRS-CVDVNECEMGAP--CQQRCYNSYGTFLCRCDQGYDLGPDGYSCNDINEC----SY 246

  Fly   709 K--LCMGLCINTPGSYQCSCPRGYILAADMNTCRDVDECATDSINQVCTGRNDICTNIRGSYKCT 771
            .  ||...|:|.||.:.|.||.||.|... ..|:||:||.|.|  ..| |...:|.||.|.::|.
Zfish   247 SSILCQYQCVNEPGKFSCVCPEGYELLGS-RLCQDVNECETGS--HQC-GEGQVCVNIHGGHQCV 307

  Fly   772 TVN-CPLGYSIDPEQKNRCRQNLNFCE--GEECYTQPSAFTYNFITFVSKLMIPPDGRTIFTLRG 833
            :.| |...|.  ...:|||     .|.  ..||...|.:..:.:::..|:..:|.|
Zfish   308 SANRCQEPYI--QVSENRC-----ICPVVKPECRDLPFSIVHRYMSITSERSVPSD--------- 356

  Fly   834 PLWYDNIEFDLKIVRIQATTNIQKATDGSFDTLQ---------------NNNQVNVILKKSLEGP 883
                        |.:||||:    ...|::::.:               ||....::|.:::.||
Zfish   357 ------------IFQIQATS----VYPGAYNSFRIRSGDQNEEFYIRQINNISAMLVLARTVTGP 405

  Fly   884 QDIELELSMTVYTNGMP-RGKSVAKLFLFVSQHTF 917
            ::..|:|.|......|. :..||.:|.:::..|.|
Zfish   406 KEYVLDLEMQSVNPLMNYQTSSVLRLAVYIGPHVF 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_001284712.1	vWFA	<189..227	CDD:294047
		EGF_CA	251..293	CDD:238011
		EGF_CA	328..>363	CDD:214542
		EGF_CA	519..564	CDD:214542	10/45 (22%)
		EGF_CA	565..601	CDD:238011	16/35 (46%)
		EGF_CA	611..651	CDD:284955	15/39 (38%)
		vWFA	<655..695	CDD:294047	19/40 (48%)
		cEGF	678..701	CDD:289433	12/22 (55%)
		EGF_CA	698..>730	CDD:214542	15/33 (45%)
		cEGF	721..744	CDD:289433	9/22 (41%)
efemp2b	NP_001153830.1	EGF_CA	120..153	CDD:214542	16/32 (50%)
		EGF_CA	161..190	CDD:214542	12/32 (38%)
		cEGF	180..203	CDD:315355	11/25 (44%)
		vWFA	<195..235	CDD:320736	19/42 (45%)
		vWFA	<238..273	CDD:320736	19/38 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910