DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31999 and egfl6

DIOPT Version :9

Sequence 1:	NP_001284712.1	Gene:	CG31999 / 43777	FlyBaseID:	FBgn0051999	Length:	917	Species:	Drosophila melanogaster
Sequence 2:	XP_017213153.1	Gene:	egfl6 / 436730	ZFINID:	ZDB-GENE-040718-157	Length:	539	Species:	Danio rerio

Alignment Length:	372	Identity:	92/372 - (24%)
Similarity:	125/372 - (33%)	Gaps:	147/372 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   305 KDRKCVKIQS----CDKGFSLHNGTCSDIDECSH----KSLNNCHVNSNQECVN--TVGSYSCNC 359
            :.|:.:.:.|    |..|..|         ||.:    .:...|....:..|.:  .||...|.|
Zfish    24 RQRRQISVMSGLGVCRYGSRL---------ECCYGWKKNTKGQCEAQCDLGCKHGECVGPNKCKC 79

  Fly   360 LPGFNLDATLNKC-VDINECSINNHNCLPTQRCDNTIGSYICTRLQSCGTGYTLNAETGNCDDDD 423
            .||:    |...| .|:|||.:....|  ..||.||.|||:|    .|..||.|..: |:|.:..
Zfish    80 FPGY----TGKTCSQDLNECGLKPRPC--EHRCMNTFGSYMC----YCLNGYMLMPD-GSCANSR 133

  Fly   424 ECTLSTHNCPSNYDCHNTRGSFRCYRKISTMLTTRTTSTTVPPLSLENARRSFTSRYPYPLAVHP 488
            .|:|:  :|  .|.|...:...||
Zfish   134 TCSLA--HC--QYGCEEVQSEVRC----------------------------------------- 153

  Fly   489 EYSQNNDSISTNRRVDCSPGFYRNTLGACIDTNECMEQNPCGNHERCINTNGHFRCESLLQCSPG 553
                                                                       |..|||
Zfish   154 -----------------------------------------------------------LCPSPG 159

  Fly   554 YKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGFVCSCPIGHELKRSIGGASTCVDTNECALE 618
            .:...|||:|.|||||.||::.|...:.|.|..|.:.|.|..|::|| .|.|...|||.|||...
Zfish   160 LQLGSDGKTCEDIDECATGKNQCPFNRQCTNTFGSYYCKCQPGYDLK-YINGKYDCVDVNECTSN 223

  Fly   619 QRVCPLNAQCFNTIGAYYCECKAGFQKKSDGNNSTQCFDIDECQVIP 665
            ...|..:|:|.||:|:|.|:||.||:...        ||   |.|.|
Zfish   224 THKCSHHAECINTLGSYKCKCKQGFRGSG--------FD---CSVKP 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_001284712.1	vWFA	<189..227	CDD:294047
		EGF_CA	251..293	CDD:238011
		EGF_CA	328..>363	CDD:214542	9/40 (23%)
		EGF_CA	519..564	CDD:214542	7/44 (16%)
		EGF_CA	565..601	CDD:238011	15/35 (43%)
		EGF_CA	611..651	CDD:284955	16/39 (41%)
		vWFA	<655..695	CDD:294047	5/11 (45%)
		cEGF	678..701	CDD:289433
		EGF_CA	698..>730	CDD:214542
		cEGF	721..744	CDD:289433
egfl6	XP_017213153.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I11922
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000