DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31999 and adgrl4

DIOPT Version :9

Sequence 1:	NP_001284712.1	Gene:	CG31999 / 43777	FlyBaseID:	FBgn0051999	Length:	917	Species:	Drosophila melanogaster
Sequence 2:	NP_998532.2	Gene:	adgrl4 / 406676	ZFINID:	ZDB-GENE-040426-2689	Length:	735	Species:	Danio rerio

Alignment Length:	254	Identity:	65/254 - (25%)
Similarity:	95/254 - (37%)	Gaps:	76/254 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   547 LLQCSPGYKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGFVCSCPIGHELKRSIGGASTCVD 611
            ||..:..:.|.:|  .|..:|.|    .:|.....|.:     :|.|..|:    :..|.|.|.|
Zfish    11 LLLFAAWFSSLLD--PCRFLDIC----QSCHPNADCDD-----ICKCRTGY----TGNGISDCRD 60

  Fly   612 TNECALEQRVCPLNAQCFNTIGAYYCECKAGFQKKSDGNNSTQCFDIDECQVIPGLCQQKCLNFW 676
            .|||.....:|.|:|.|.|.:|.|||.|.:||.     :|.|:.|..:
Zfish    61 DNECETVPEICGLHANCTNYVGGYYCNCLSGFI-----SNGTEQFQTN----------------- 103

  Fly   677 GGYRCTCNSGYQLGPDNRTCNDINECEVHKDYKLC--MGLCINTPGSYQCSCPRGYILAAD---- 735
                           |..:||||||||  :|.| |  ...|.|..||:.|||.|||...|.
Zfish   104 ---------------DGTSCNDINECE--EDRK-CGPNSKCHNNIGSFICSCLRGYTSPAGPWFM 150

  Fly   736 --------MNT---CRDVDECATDSINQVCTGRNDICTNIRGSYKCTTVNCPLGYSIDP 783
                    .|:   |....:|..:::|...    :..||:..|.:...:......::.|
Zfish   151 PNHGTDCIENSKIHCHQDHKCTKETVNSTL----ERMTNLSISERLKEIRYQTSAALSP 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_001284712.1	vWFA	<189..227	CDD:294047
		EGF_CA	251..293	CDD:238011
		EGF_CA	328..>363	CDD:214542
		EGF_CA	519..564	CDD:214542	4/16 (25%)
		EGF_CA	565..601	CDD:238011	7/35 (20%)
		EGF_CA	611..651	CDD:284955	16/39 (41%)
		vWFA	<655..695	CDD:294047	2/39 (5%)
		cEGF	678..701	CDD:289433	5/22 (23%)
		EGF_CA	698..>730	CDD:214542	17/33 (52%)
		cEGF	721..744	CDD:289433	10/37 (27%)
adgrl4	NP_998532.2	EGF_CA	34..56	CDD:304395	6/30 (20%)
		EGF_CA	60..93	CDD:238011	15/32 (47%)
		EGF_CA	110..143	CDD:214542	19/35 (54%)
		GAIN	188..386	CDD:293098	2/18 (11%)
		GPS	416..457	CDD:280071
		7tm_4	469..705	CDD:304433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000