DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31999 and susd1

DIOPT Version :9

Sequence 1:	NP_001284712.1	Gene:	CG31999 / 43777	FlyBaseID:	FBgn0051999	Length:	917	Species:	Drosophila melanogaster
Sequence 2:	NP_989222.1	Gene:	susd1 / 394830	XenbaseID:	XB-GENE-944710	Length:	904	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	95/363 - (26%)
Similarity:	136/363 - (37%)	Gaps:	126/363 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   544 CESL-LQCSPGYKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGFVCSCPIGHELKRSIG-GA 606
            |.:| |.|....:....|:     |.|    ..|.....|..||..:.|.|..|     .|| |.
Frog    15 CLALALPCHAQLQDDASGQ-----DVC----KKCHTNATCLERNKKYSCICNYG-----LIGNGR 65

  Fly   607 STCVDTNECAL-EQRVCPLNAQCFNTIGAYYCECKAGFQKKSD-----GNNSTQCFDIDECQVIP 665
            :.|:|.:||.: ..::|..:..|.||.|:::|.|..|::..::     .|:.|.|.|||||: ..
Frog    66 THCLDKDECQIGSYKICGNHTACHNTHGSFFCVCLDGYRPSNNHKHFIPNDGTFCTDIDECE-SA 129

  Fly   666 GLC--QQKCLNFWGGYRCTCNSGYQL---------GPDNRTCNDINECEVHKDYKLC--MGLCIN 717
            .:|  :.||.|..|.|.|.|..||||         ..|| .|.|::|||..   .:|  ...|.|
Frog   130 DICGYKGKCKNIPGSYECYCMDGYQLKNGTEPFQANSDN-GCVDVDECEAE---DICGHNAKCRN 190

  Fly   718 TPGSYQCSCPRGYIL---------AADMNTCRDVD--------------ECATDSINQVCTGRND 759
            .||:::|.|..||.|         .:.||.|..:|              |..|...:|| |.|.|
Frog   191 VPGNHECYCMEGYRLNNGTEPFQAHSRMNLCSVIDCGQPPALLHSQMNLEGNTTFGSQV-TYRCD 254

  Fly   760 ------------ICTNIRGSYK-----CTTVNC---PL--------------------------- 777
                        |||: .|:::     ||.::|   |:
Frog   255 AGFTATAGRAMSICTS-NGTWEGASLVCTVIDCGFPPVVPNALINSSDNTTFGSNVTYTCMKGYV 318

  Fly   778 ---GYSIDPEQKNRCRQNLNF------CEGEECYTQPS 806
               ||..     .||.||..:      |:..:|...||
Frog   319 ASSGYGF-----ARCAQNGKWEAATLSCQVVDCGQPPS 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_001284712.1	vWFA	<189..227	CDD:294047
		EGF_CA	251..293	CDD:238011
		EGF_CA	328..>363	CDD:214542
		EGF_CA	519..564	CDD:214542	5/20 (25%)
		EGF_CA	565..601	CDD:238011	9/35 (26%)
		EGF_CA	611..651	CDD:284955	11/45 (24%)
		vWFA	<655..695	CDD:294047	20/50 (40%)
		cEGF	678..701	CDD:289433	11/31 (35%)
		EGF_CA	698..>730	CDD:214542	11/33 (33%)
		cEGF	721..744	CDD:289433	9/45 (20%)
susd1	NP_989222.1	EGF_CA	39..66	CDD:389777	10/31 (32%)
		EGF_CA	70..108	CDD:214542	11/37 (30%)
		EGF_CA	122..157	CDD:238011	17/35 (49%)
		EGF_CA	172..204	CDD:214542	12/34 (35%)
		PHA02927	190..394	CDD:222943	37/169 (22%)
		CCP	406..462	CDD:153056
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000