DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31999 and Matn3

DIOPT Version :9

Sequence 1:	NP_001284712.1	Gene:	CG31999 / 43777	FlyBaseID:	FBgn0051999	Length:	917	Species:	Drosophila melanogaster
Sequence 2:	NP_001382499.1	Gene:	Matn3 / 313954	RGDID:	1305085	Length:	481	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	74/264 - (28%)
Similarity:	101/264 - (38%)	Gaps:	76/264 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   509 FYRNTLGACIDTNECMEQNPC-------GNHE---RCINT-NGHFRCESLLQCSPGYKSTVDGKS 562
            ||..|.|.....:...::..|       |.|:   .|::. :|...||    ||.||....|||:
  Rat   238 FYVETYGVIEKLSARFQETFCALDQCMLGTHQCQHVCVSDGDGRHHCE----CSQGYTLNADGKT 298

  Fly   563 CIDIDECDTGEHNCGERQICRN-RNGGFVCSCPIGHELKRSIGGASTCVDTNECALEQRVCPLNA 626
            |..||:|....|.|  .|||.| |||.:.|.|..|:.|.   ....||...::|||
  Rat   299 CSAIDKCALNTHGC--EQICVNDRNGSYHCECYEGYTLN---ADRKTCAAQDKCAL--------- 349

  Fly   627 QCFNTIGAYYCECKAGFQKKSDGNNSTQCFDIDECQVIPGLCQQKCLNFW-GGYRCTCNSGYQLG 690
               .|.|                                  ||..|:|.. |.:.|.|..||.|.
  Rat   350 ---GTHG----------------------------------CQHICVNDGAGSHHCECFEGYTLN 377

  Fly   691 PDNRTCNDINECEV--HKDYKLCMGLCINTPG-SYQCSCPRGYILAADMNTCRDVDEC-ATDSIN 751
            .|.:||:..::|.:  |.    |..:|::... ||.|.|..||.|..|..||.|::|. :..||.
  Rat   378 ADKKTCSVRDKCALGTHG----CQHICVSDGAVSYHCDCFPGYTLNDDKKTCSDIEEVRSLISIE 438

  Fly   752 QVCT 755
            ..|:
  Rat   439 DACS 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_001284712.1	vWFA	<189..227	CDD:294047
		EGF_CA	251..293	CDD:238011
		EGF_CA	328..>363	CDD:214542
		EGF_CA	519..564	CDD:214542	14/55 (25%)
		EGF_CA	565..601	CDD:238011	16/36 (44%)
		EGF_CA	611..651	CDD:284955	5/39 (13%)
		vWFA	<655..695	CDD:294047	11/40 (28%)
		cEGF	678..701	CDD:289433	8/22 (36%)
		EGF_CA	698..>730	CDD:214542	8/34 (24%)
		cEGF	721..744	CDD:289433	11/22 (50%)
Matn3	NP_001382499.1	vWFA	75..298	CDD:412136	17/63 (27%)
		FXa_inhibition	305..341	CDD:405372	14/40 (35%)
		FXa_inhibition	347..383	CDD:405372	16/81 (20%)
		FXa_inhibition	389..425	CDD:405372	12/39 (31%)
		Matrilin_ccoil	438..478	CDD:402147	1/5 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000