DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31999 and Scube3

DIOPT Version :9

Sequence 1:NP_001284712.1 Gene:CG31999 / 43777 FlyBaseID:FBgn0051999 Length:917 Species:Drosophila melanogaster
Sequence 2:XP_008771027.1 Gene:Scube3 / 294297 RGDID:1304880 Length:1015 Species:Rattus norvegicus


Alignment Length:605 Identity:156/605 - (25%)
Similarity:216/605 - (35%) Gaps:220/605 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   233 TQICPSGYNLDKLDN------KCI-----DIDECREDLHDCKSSQYCHNTNGGYHCLNVKEKECP 286
            |...|.|....||..      .|:     |:|||.|....|.....|.||...|.|:        
  Rat     5 TGTLPLGNTPSKLTRDTSSVLMCLPLPGPDVDECVEGTDHCHIDAICQNTPRSYKCI-------- 61

  Fly   287 PGFHYDHDYDACKDDYKCKDRKCVKIQSCDKGFSLHNGTCSDIDECSHKSLNNC-HVNSNQECVN 350
                                        |..|::.....|.|:|||..:....| |     :|||
  Rat    62 ----------------------------CKSGYTGDGKHCKDVDECEREDNAGCVH-----DCVN 93

  Fly   351 TVGSYSCNCLPGFNLDATLNKCVDINECSINNHNCLPTQRCDNTIGSYICTRLQSCGTGYTLNAE 415
            ..|:|.|.|..||:|....:.|:|::||:..|..|  .|.|.|.:|||.|    .|..|:.|:..
  Rat    94 IPGNYRCTCYDGFHLAHDGHNCLDVDECAEGNGGC--QQSCVNMMGSYEC----HCRDGFFLSDN 152

  Fly   416 TGNC----DDDDECTLSTHNCPSNYDCHNT-RGSFRCYRKISTMLTTRTTSTTVPPLSLENARRS 475
            ...|    ::...|....|.|.  :.|..| :|...|                            
  Rat   153 QHTCIQRPEEGMNCMNKNHGCA--HICRETPKGGIAC---------------------------- 187

  Fly   476 FTSRYPYPLAVHPEYSQNNDSISTNRRVDCSPGF--------------YRNTLGACIDTNECMEQ 526
                                        :|.|||              |.|  |.|..|.:..||
  Rat   188 ----------------------------ECRPGFELTKNQRDCKLTCNYGN--GGCQHTCDDTEQ 222

  Fly   527 NP-CGNHERCINTNGHFRCESLLQCSPGYKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGFV 590
            .| ||.|.:                   :....|||:||            |||::.::      
  Rat   223 GPRCGCHVK-------------------FVLHTDGKTCI------------GERRLEQH------ 250

  Fly   591 CSCPIGHELKRSIGGASTCVDTNECALEQRVCPLNAQCFNTIGAYYCECKAGFQKKSDGNNSTQC 655
                          |.:..|....||:....|  :::|.:.....:|.|..||..:.|...   |
  Rat   251 --------------GPTQAVSNETCAVNNGGC--DSKCHDAATGVHCSCPVGFMLQPDRKT---C 296

  Fly   656 FDIDECQVIPGLCQQKCLNFWGGYRCTCNSGYQLGPDNRTCNDINECEVHKDYKLCMGLCINTPG 720
            .|||||::..|.|...|.|..|.:.|:|..||:|..:.|:|.||:||...   :.|..:|:||||
  Rat   297 KDIDECRLHNGGCDHICRNTVGSFECSCKKGYKLLINERSCQDIDECSFD---RTCDHMCVNTPG 358

  Fly   721 SYQCSCPRGYILAADMNTCRDVDECATDSINQVCTGRNDICTNIRGSYKCTTVNCPLGYSIDPEQ 785
            |:||.|.|||:|.. ::.|.|||||   |||:  .|....|.|..|||:||   ||.|       
  Rat   359 SFQCLCHRGYLLYG-ISHCGDVDEC---SINK--GGCRFGCINTPGSYQCT---CPAG------- 407

  Fly   786 KNRCRQNLNFCEGEECYTQP 805
            :.|...|     |::| |:|
  Rat   408 QGRLHWN-----GKDC-TEP 421

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31999NP_001284712.1 vWFA <189..227 CDD:294047
EGF_CA 251..293 CDD:238011 11/41 (27%)
EGF_CA 328..>363 CDD:214542 13/35 (37%)
EGF_CA 519..564 CDD:214542 10/45 (22%)
EGF_CA 565..601 CDD:238011 3/35 (9%)
EGF_CA 611..651 CDD:284955 9/39 (23%)
vWFA <655..695 CDD:294047 16/39 (41%)
cEGF 678..701 CDD:289433 9/22 (41%)
EGF_CA 698..>730 CDD:214542 15/31 (48%)
cEGF 721..744 CDD:289433 11/22 (50%)
Scube3XP_008771027.1 EGF_3 38..73 CDD:289699 10/70 (14%)
FXa_inhibition 81..115 CDD:291342 12/38 (32%)
FXa_inhibition 121..156 CDD:291342 13/40 (33%)
FXa_inhibition 166..202 CDD:291342 11/93 (12%)
FXa_inhibition 206..241 CDD:291342 14/55 (25%)
FXa_inhibition 261..296 CDD:291342 9/39 (23%)
FXa_inhibition 302..337 CDD:291342 12/34 (35%)
vWFA <334..370 CDD:294047 19/38 (50%)
EGF_CA 378..419 CDD:214542 23/61 (38%)
GCC2_GCC3 664..711 CDD:285001
GCC2_GCC3 718..765 CDD:285001
GCC2_GCC3 774..821 CDD:285001
CUB 826..937 CDD:238001
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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