Protein Alignment CG31999 and Fbln5

DIOPT Version :9

• Sequence 1: NP_001284712.1
• Gene: CG31999 / 43777
• FlyBaseID: FBgn0051999
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001348916.1
• Gene: Fbln5 / 23876
• MGIID: 1346091
• Length: 461
• Species: Mus musculus
• Alignment Length: 531
• Identity: 157/531 - (29%)
• Similarity: 226/531 - (42%)
• Gaps: 124/531 - (23%)

  Fly   404 QSCGTGYTLNAETGNCDDDDECTLSTHNCPSNYDCHNTRGSFRCYRKISTMLTTRTTSTTVPPLS 468
            |.|..|:.|:.::|.|.|.|||......|..:..|.|..|.:.|        ..||......|.|
Mouse    38 QQCTNGFDLDRQSGQCLDIDECRTIPEACRGDMMCVNQNGGYLC--------IPRTNPVYRGPYS 94

  Fly   469 LENARRSFTSRY--PYPLAVHPEYSQNNDSISTNRRVDCSPGFYRNTLGACIDTNECMEQNPCGN 531
                 ..:::.|  |||.|..|..:.|..:||                            .|
Mouse    95 -----NPYSTSYSGPYPAAAPPVPASNYPTIS----------------------------RP--- 123

  Fly   532 HERCINTNGHFRCESLLQCSPGYKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGFVCSCPIG 596
                            |.|..||:.. :|..|:|:|||.|..|.|...|||.|..||:.|||..|
Mouse   124 ----------------LVCRFGYQMD-EGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDG 171

  Fly   597 HELKRSIGGASTCVDTNECALEQRVCPLNAQCFNTIGAYYCECKAGFQKKSDGNNSTQCFDIDEC 661
            :.|..     ..|:|.:||    |.......|.|..|:|.|.|..||....||.:   |.|::||
Mouse   172 YWLLE-----GQCLDIDEC----RYGYCQQLCANVPGSYSCTCNPGFTLNDDGRS---CQDVNEC 224

  Fly   662 QVIPGLCQQKCLNFWGGYRCTCNSGYQLGPDNRTCNDINECEVHKDYKLCMGLCINTPGSYQCSC 726
            :. ...|.|.|:|.:|.:.|.|:.||:|..|...|:|::||...:  .||...|:|.||||.|||
Mouse   225 ET-ENPCVQTCVNTYGSFICRCDPGYELEEDGIHCSDMDECSFSE--FLCQHECVNQPGSYFCSC 286

  Fly   727 PRGYILAADMNTCRDVDECATDSINQVCTGRNDICTNIRGSYKC-TTVNCPLGYSIDPEQKNRCR 790
            |.||:|..|..:|:|::||  :..|..||.. ..|.|::|.:|| ..::|...|.:..|  |||
Mouse   287 PPGYVLLDDNRSCQDINEC--EHRNHTCTSL-QTCYNLQGGFKCIDPISCEEPYLLIGE--NRC- 345

  Fly   791 QNLNFCEGE--ECYTQPSAFTYNFITFVSKLMIPPDGRTIFTLRGPLWYDNIEFDLKIVRIQATT 853
                .|..|  .|..||....|..:..||...:|.|                     |.::||||
Mouse   346 ----MCPAEHTSCRDQPFTILYRDMDVVSGRSVPAD---------------------IFQMQATT 385

  Fly   854 ---------NIQKATDGSFDTLQNNNQVN--VILKKSLEGPQDIELELSM-TVYTNGMPRGKSVA 906
                     .|:...:|....::....::  :::.:.::||:||:|:|.| ||.|....||.||.
Mouse   386 RYPGAYYIFQIKSGNEGREFYMRQTGPISATLVMTRPIKGPRDIQLDLEMITVNTVINFRGSSVI 450

  Fly   907 KLFLFVSQHTF 917
            :|.::|||:.|
Mouse   451 RLRIYVSQYPF 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_001284712.1	vWFA	<189..227	CDD:294047
		EGF_CA	251..293	CDD:238011
		EGF_CA	328..>363	CDD:214542
		EGF_CA	519..564	CDD:214542	6/44 (14%)
		EGF_CA	565..601	CDD:238011	18/35 (51%)
		EGF_CA	611..651	CDD:284955	14/39 (36%)
		vWFA	<655..695	CDD:294047	15/39 (38%)
		cEGF	678..701	CDD:289433	8/22 (36%)
		EGF_CA	698..>730	CDD:214542	15/31 (48%)
		cEGF	721..744	CDD:289433	12/22 (55%)
Fbln5	NP_001348916.1	vWFA	<134..178	CDD:320736	20/48 (42%)
		cEGF	200..223	CDD:315355	9/25 (36%)
		EGF_CA	220..258	CDD:214542	14/38 (37%)
		FXa_inhibition	271..299	CDD:317114	15/27 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11163
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.870