Protein Alignment CG31999 and LOC108191777

DIOPT Version :10

• Sequence 1: NP_726551.2
• Gene: CG31999 / 43777
• FlyBaseID: FBgn0051999
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_068080933.1
• Gene: LOC108191777 / 108191777
• -ID: -
• Length: 1117
• Species: Danio rerio
• Alignment Length: 908
• Identity: 176/908 - (19%)
• Similarity: 280/908 - (30%)
• Gaps: 366/908 - (40%)

  Fly    83 CELGRLAALDGTRCDGEGNV----TSSSY---ATCCRSCQIGLAVKASKANCKDPLFSFIFLIES 140
            |..|....|||.....|..|    ...||   ..||.|..|.:.|||...|      .:::.:.|
Zfish   220 CNTGMNLVLDGPHPQIEDGVVIREVCGSYYWSRGCCDSKSIPIRVKACPGN------YYVYELVS 278

  Fly   141 YRACCYGSADFKDQPGIDEIDKANSITDEGELPFVSEEDMNVTIVLTGDDDICGKIENLCAHICE 205
            .:..|.|..                 ||   :..:|:      :|.|...||.
Zfish   279 PQIWCSGYC-----------------TD---VSTISQ------VVSTASPDII------------ 305

  Fly   206 NTFDAYQCKCHPGFMLDNNNVTCSPMK--------TQICPSGYN-LDKLDNKCIDIDECREDLHD 261
                       ||:.::.|...|:..:        ||:..|.|| ::..||.
Zfish   306 -----------PGYTINFNYDQCNNYEILNDYWRSTQVYWSVYNDVNGYDNN------------- 346

  Fly   262 CKSSQYCHNTNGGYHC----LNVKEKECPPGF-----------HYDH----------DYDACKDD 301
                   |..:|.|..    |:.:..|....|           |..|          :...|::|
Zfish   347 -------HEWDGWYRLLLDGLSAQMPEWSVTFMTCGGVTALWLHGSHPQLEDGVVTREVYGCRND 404

  Fly   302 YKCKDR-KCVKIQSCDKGFSLHNGT-----------CS------DIDEC-SHKSLNNCHVNSNQE 347
            ...:.| ..:::::|...:.::..|           |:      .:|.| ::.||       ::.
Zfish   405 LSSRYRSNPIQVKACPGDYYVYKFTRPPISIPAPRYCAVSFPTPSVDPCYNYNSL-------DEP 462

  Fly   348 CVNTVGSYSCNCLPGFNLDATL-----------NKCVDINECSINNHNCLPTQRCDNTIGSYICT 401
            ..:|...|:.|   |:|.|.::           |:...:.|..:|...|          |:|...
Zfish   463 WRSTDNFYNYN---GYNCDWSVAWNGWYRLFYNNQSAQMPESCVNQGMC----------GTYYPL 514

  Fly   402 RLQS--------------CGTGYTLNAETGNCDDDDECTLSTH-----NCPSNYDCHNTRGSFRC 447
            .|..              |.:||:      .|     ||.::|     .||.||..:..:....|
Zfish   515 WLNGSHPQVEDGVVLRHVCASGYS------GC-----CTYTSHPIRVKACPGNYYVYEFKQPRIC 568

  Fly   448 ------YRKISTMLTTR---------TTSTTVPP-------LSLENARRSFTSRYPYPLAVHPEY 490
                  ..:.||.:||.         |..||.||       |.|:...|:..
Zfish   569 SAYCVAANQSSTAVTTTQPITSIDFITPPTTAPPVDPCNNFLILDEPWRATN------------- 620

  Fly   491 SQNNDSISTNRRVDCSPGFYRNTL-GACI---DTNECMEQNPCGNHERCINTNGHFRCESLLQCS 551
            :|::..:..:|.|..| |:||..: |..:   ||  |:::..||       ||      :.|..|
Zfish   621 NQHSSQLMCDRAVSWS-GWYRLFINGQSVQMPDT--CVDEYSCG-------TN------APLWLS 669

  Fly   552 PGYKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGF-VCSCPIG---HELKRSIG-GASTCVD 611
            .|:.:..||  .:..:.|....::|     |..::... |.:||.|   :|..|..| ..:.|.|
Zfish   670 GGHPTLEDG--VVSRNVCAHWNNDC-----CYFQSNPIQVKACPGGFYVYEFVRPSGCNLAYCAD 727

  Fly   612 ---------------TNECALEQRV-------------CPLNAQCFNTIGAYYCECKAGFQKKSD 648
                           |.|...|...             |....:|....|.|.|.|..|.||...
Zfish   728 VRFNTSYTTDMPETTTTETTAESTTIISAVRNPCSELNCSKEERCGMKNGVYGCLCNKGLQKHRA 792

  Fly   649 GNNSTQCFDIDECQVIPGLCQQKCLNFWGGYRCTCNSGYQLGPDNRTCNDINECEVHKDYKLCMG 713
            ..:|   ||.:|                   .|..:||..         .::.|::.:.......
Zfish   793 PKDS---FDFNE-------------------TCESSSGSM---------SVSRCQLFEAGFSAEH 826

  Fly   714 LCINTPGSYQCSCPRGYIL--AADMNTCRDVDECATDSINQVCTGRNDICTN------------- 763
            |.:|.|     || ||.:.  ..:.|...|...|.|   |.|..|.:.|.:|
Zfish   827 LHLNDP-----SC-RGTVQNGRVEFNFDNDQHICGT---NLVANGSHFIYSNYIVGTPGREGLIS 882

  Fly   764 ----IRGSYKCT---TVNCPLGYSIDPEQKNRCRQNLNFCEG----------EECYTQPSAFT 809
                ::.|:.|.   |....:...|:|.| :...:.|...||          :|.:|||  ||
Zfish   883 RVRILKLSFSCVYPQTQTLSMNVEINPLQ-STVHKVLPSGEGVYQVRMVPYVDEEFTQP--FT 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_726551.2	vWFA	<189..227	CDD:469594	5/37 (14%)
		EGF_CA	251..293	CDD:238011	7/56 (13%)
		EGF_CA	328..>363	CDD:214542	7/35 (20%)
		EGF_CA	421..447	CDD:429571	7/30 (23%)
		EGF_CA	519..564	CDD:214542	12/44 (27%)
		EGF_CA	565..601	CDD:238011	8/39 (21%)
		EGF_CA	611..642	CDD:429571	10/58 (17%)
		FXa_inhibition	661..696	CDD:464251	3/34 (9%)
		EGF_CA	698..>730	CDD:214542	7/31 (23%)
		cEGF	723..744	CDD:463661	6/22 (27%)
LOC108191777	XP_068080933.1	Zona_pellucida	814..1050	CDD:459673	32/141 (23%)