Protein Alignment CG31999 and si:ch73-181m17.1

DIOPT Version :10

• Sequence 1: NP_726551.2
• Gene: CG31999 / 43777
• FlyBaseID: FBgn0051999
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_021336080.3
• Gene: si:ch73-181m17.1 / 100330610
• ZFINID: ZDB-GENE-131122-49
• Length: 2316
• Species: Danio rerio
• Alignment Length: 1123
• Identity: 206/1123 - (18%)
• Similarity: 329/1123 - (29%)
• Gaps: 421/1123 - (37%)

  Fly    61 LWLGLCHSTLE-VCCSRELDHQDCELGRLAALDGTRCDGEGNVTSSS--YATCCRSCQIGLAVKA 122
            |:|...|..|| ...:|::      ||..:....::|   ||..|:|  ...|.....:...||.
Zfish   120 LYLNASHPKLEDGVVTRDV------LGMSSGWSFSQC---GNYRSNSIQVKACPGDYYVYELVKP 175

  Fly   123 S-----KANC--------KDPLFSFIFLIESYRA-------CCYGSADFKD------------QP 155
            |     ...|        .||.:::..|...:||       .|.|:..:..            .|
Zfish   176 STFMPRPTYCTVAFNNISNDPCYNYESLDRPWRATNESGFFICDGAFPWNGWYRLFCNGMNIRMP 240

  Fly   156 ----GIDEIDKANSITDEGELPFVSEEDMNVTIVLTGDDDICGKIE-NLCA-------------- 201
                |.:..:..||::..|..|.:.:   .|.|     .::||.:. ..||
Zfish   241 ESCIGANGCNTQNSLSLNGPHPQIED---GVVI-----RELCGSVGFGCCAFRSTPIRVKACPGD 297

  Fly   202 -HICENTFDAYQCKCHPGFMLDNNNVTCSPMKTQICPSG-------------YNLDKLDNKCIDI 252
             ::.|.:..::.|.   |:.:|.:.::..|..:....:|             ||.:.|||.....
Zfish   298 YYVYELSDPSFPCS---GYCIDVSTLSQLPTTSPAAITGSSITLINSDYDPCYNYNSLDNHWRST 359

  Fly   253 -DECREDLHDCKSSQ----------------------YCHNTNGGYHCL------------NVKE 282
             :....|.|....|:                      :.|.:.|||..|            .|..
Zfish   360 HNNWLADEHAYDDSRVHWDGWYRLFINGSSAEIPERCFSHMSCGGYVSLWLGDPHPQLEDGVVTR 424

  Fly   283 KECPPGFHYDHDY-------DACKDDY----------------KCKD------RKCVKIQSCDKG 318
            |.....:|..::|       .||..:|                .|.|      ..|.:....|.|
Zfish   425 KVYGSSYHQCNNYRSDPIQVKACPGNYYVYKLIRPKLTIPAPVYCADVRTPVSEPCTQYSILDDG 489

  Fly   319 ------------FSLHNGTCSDIDECSHKSLNNCHVNSNQECVNTVGSYS-CNCLPGFNLDATLN 370
                        :::|:.|..:........||......::.||    ||| |....|..|:|:..
Zfish   490 WRGLQVLGHNSPYNVHDDTLVEWSGWYRLYLNGTSAQLSEWCV----SYSECGGGTGLYLNASHP 550

  Fly   371 KCVD---------------INECSINNHNCLPTQRCDNTIGSYICTRLQSCGTGY---TLNAETG 417
            |..|               .::|.....|.:..:.|.   |.|....|....|..   |......
Zfish   551 KLEDGVVTRDVLGMSSGWSFSQCGNYRSNSIQVKACP---GDYYVYELVKPSTFMPRPTYCTVAF 612

  Fly   418 NCDDDDECTLSTHNCPSNYD-------CHNTRGSFRC---------YRKISTMLTTRTTSTTVPP 466
            |...||.|        .||:       ..|..|.|.|         ||.....:..|...:.:..
Zfish   613 NNISDDPC--------YNYESLDRPWRATNESGFFVCDGAFTWNGWYRLFCNGMNIRMPESCIGA 669

  Fly   467 LSLENARRSFTSRYPYPLAVHPEYSQNNDSI-----------------STNRRVDCSPG-FYRNT 513
            ... |.:.|.:...|:|        |..|.:                 ||..||...|| :|...
Zfish   670 NGC-NTQNSLSLNGPHP--------QIEDGVVIRELCGSVGFGCCAFRSTPIRVKACPGDYYVYE 725

  Fly   514 L--------GACIDT---NECMEQNPCG--------NHERCINTNG----------------HFR 543
            |        |.|||.   ::....:|..        |::.|.|.|.                |..
Zfish   726 LSDPSFPCSGYCIDVRTLSQLPTTSPAAITGSSITLNYDPCYNYNSLDNYWRTTYNNWFADEHAH 790

  Fly   544 CESLLQCSPGYKSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGFVCSCPIGHE--------LK 600
            .:|.:.....|:..::|.|. :|.|.      |.....|    ||:| |..:|..        :.
Zfish   791 DDSRVHWDGWYRLFINGSSA-EIPEW------CFTYMSC----GGYV-SLWLGDPHPQLEDGVVT 843

  Fly   601 RSIGGASTCVDTNEC-----ALEQRVCPLNAQCFNTI-------GAYYCECKAGFQKKSDGNNST 653
            |.:.|:.    .|:|     .::.:.||.|...:..|       ...||..      ..:.:|:.
Zfish   844 RKVYGSI----YNQCNYRSDPIQVKACPGNYYVYKLIRPKLTMPAPVYCAV------SFNTSNTD 898

  Fly   654 QCF---DIDE------CQVIPGLCQQKCLNFWGG-YRCTCNSGYQLGPDNRTCNDINECEVHKDY 708
            .|:   ::||      ......:|....:  |.| ||...|:.....||:...|
Zfish   899 PCYNYTNLDEPWRASNNSYFGSVCDYNVV--WNGWYRLFYNAQSVQMPDSCVSN----------- 950

  Fly   709 KLCMGLC-INTP----GSYQCSCPRGYILAADMNTCRDVDECATDSINQVCTGRNDICTNIRGSY 768
                |:| .|.|    ||:. |...|.:                  ..|||:.
Zfish   951 ----GMCGSNQPLWLNGSHP-SLEDGVV------------------TRQVCSP------------ 980

  Fly   769 KCTTVNCPLGYSIDPEQKNRCRQNLNFCEGEECYTQPSAFTYNF---ITFVSKLMIPPDGRTIFT 830
              |..:| .||:..|.|...|..|.....    .|:|: |..::   :|.:|.::......||.|
Zfish   981 --TWTDC-CGYTSHPIQVKACPGNYYVYH----LTKPT-FCSSYCAEVTEISNILASTTAVTIST 1037

  Fly   831 LRGPLWYDNIEFDLKIVRIQATTNIQKATDGSFDTLQNNNQVNVILKKSLEGPQDIELELSMTVY 895
            ...|:               ||:...     .||...|...::... :|:...|...:...|:|.
Zfish  1038 QESPI---------------ATSEAD-----PFDPCYNYTVLDNYW-RSVNNTQFSSIRCDMSVN 1081

  Fly   896 TNGMPRGKSVAKLFLFVS 913
            .||..|        |::|
Zfish  1082 WNGWYR--------LYIS 1091

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_726551.2	vWFA	<189..227	CDD:469594	8/53 (15%)
		EGF_CA	251..293	CDD:238011	11/76 (14%)
		EGF_CA	328..>363	CDD:214542	8/35 (23%)
		EGF_CA	421..447	CDD:429571	8/32 (25%)
		EGF_CA	519..564	CDD:214542	11/71 (15%)
		EGF_CA	565..601	CDD:238011	9/43 (21%)
		EGF_CA	611..642	CDD:429571	8/42 (19%)
		FXa_inhibition	661..696	CDD:464251	8/35 (23%)
		EGF_CA	698..>730	CDD:214542	7/36 (19%)
		cEGF	723..744	CDD:463661	2/20 (10%)
si:ch73-181m17.1	XP_021336080.3	None