Protein Alignment CG31999 and zgc:153932

DIOPT Version :10

• Sequence 1: NP_726551.2
• Gene: CG31999 / 43777
• FlyBaseID: FBgn0051999
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001076476.1
• Gene: zgc:153932 / 100009638
• ZFINID: ZDB-GENE-070209-223
• Length: 1121
• Species: Danio rerio
• Alignment Length: 1024
• Identity: 193/1024 - (18%)
• Similarity: 333/1024 - (32%)
• Gaps: 358/1024 - (34%)

  Fly    62 WLGLCHSTL-----EVCCSRELDHQDCELGRLAALDGTRCDGEGNVT------SSSYATCCRSCQ 115
            |..|.::.:     |.|.:|    .:|..|....|:|.....|..|.      ||.::.||....
Zfish   198 WYRLFYNGMNIQMPETCITR----LNCNTGIDLYLNGPHPQIEDGVVIREVCGSSYWSGCCDIKS 258

  Fly   116 IGLAVKASKANCKDPLFSFIF-LIESYRACCYGSADFKDQPGIDEIDKANSITDEGELPFVSEED 179
            ..:.|||...|      .::: |:.....|.....|      |:.|.:..|.|.    |.:..|.
Zfish   259 SPIRVKACPGN------YYVYELVRPPTGCSGYCTD------INTISQVASTTS----PQIITES 307

  Fly   180 MNVTIVLTGDDDICGKIENLCAHICENTFDAYQCKCHPGFMLDNNNVTCSPMKTQICPSGYNLDK 244
             :||:    :.|.|...:.|.:: |.:|..::.                  .::.||  ||
Zfish   308 -SVTL----NYDPCSNYKTLDSY-CRSTLGSWY------------------WESYIC--GY---- 342

  Fly   245 LDNKCID--------IDECREDLHD-CKSSQYCHNTNGGYHCL-----------NVKEKECPPGF 289
             |:..::        |:|....:.| |.|...|    ||:..|           .|..:|.....
Zfish   343 -DDTLVEWDGWYRLFINESSAQMPDWCASHMSC----GGFTALWLHGSHPRLQDGVVTREVFGSN 402

  Fly   290 HYDHDYDACKDDYKCKDRKCVKIQSCDKGFSLHNGT-----------CS------DIDECSH--- 334
            :||..:      |:...   :::::|...:.::..|           |:      .:|.|.:
Zfish   403 YYDCSH------YRSNP---IQVKACAGDYYVYKFTKPTVSLPAPVYCAVSSATPSVDPCYNYTS 458

  Fly   335 -----KSLNNCHVNSNQECVNTVGSYSCNCLPGFNL-----DATL-NKCVDINECSINN---HNC 385
                 :|.:|.:.|:.....:::..|:......:.|     :|.: ..||:...|...|   .|.
Zfish   459 LDEPWRSTDNYYNNNYYYYYHSLCDYNVEWNGWYRLFYNGQNAQMPESCVNPYMCGTYNPMWFNE 523

  Fly   386 LPTQRCDNTIGSYIC-TRLQSCGTGYTLNAETGNCDDDDECTLSTHNCPSNYDCHNTRGSFRCYR 449
            ...|..|..:...|| :..:.| ..||..|            :....||         |.:..|.
Zfish   524 SHPQLEDGVVFRQICISDFRGC-CSYTSKA------------IRVKACP---------GDYYVYE 566

  Fly   450 KISTML--------TTRTTSTTVPPLSLENARRSFTSRYPYPLAVHPEY-------------SQN 493
            .:..::        |.::|:|...||: ::...|.|:..|   .|.|.|             :||
Zfish   567 FVKPIICGTYCLEATNQSTTTASIPLT-QSITPSITTTAP---PVDPCYNYFILDEPWRATSNQN 627

  Fly   494 NDSISTNRRVDCSPGFYRNTL-GACI---DTNECMEQNPCGNHERCINTNGHFRCESLLQCSPGY 554
            :..:..:..|..| |:||..: |..:   ||  |:::|.||       ||      :.|..|.|:
Zfish   628 SSQLMCDSAVSWS-GWYRLFINGQSVQMPDT--CVDENSCG-------TN------APLWLSGGH 676

  Fly   555 KSTVDGKSCIDIDECDTGEHNCGERQICRNRNGGF-VCSCPIG---HELKR-SIGGASTCVD--- 611
            .:..||  .:..:.|....:||     |..::... |.:||.|   :|..| :....:.|.|
Zfish   677 PTLEDG--VVSRNFCAHWSNNC-----CYFQSNPIQVKACPGGFYVYEFVRPTTCNLAYCADVRF 734

  Fly   612 ------------TNECALEQRV-------------CPLNAQCFNTIGAYYCECKAGFQKKSDGNN 651
                        |.|.|.|.|.             |....:|....|.|.|.|..|.||:....:
Zfish   735 NTSYTTDIPETTTTETAAETRTIIFDDRNPCSELNCSKEERCGMKNGVYGCLCNKGHQKQRAAQD 799

  Fly   652 STQCFDIDECQVIPGLCQQKCLNFWGGYRCTCNSGYQLGPDNRTCNDINECEVHKDYKLCMGLCI 716
            |   ||.:|                   .|..:||..         .::.|::.:.......|.:
Zfish   800 S---FDFNE-------------------TCESSSGSM---------SVSRCQLFEAGFSAEHLHL 833

  Fly   717 NTPGSYQCSCPRGYIL--AADMNTCRDVDECATDSINQVCTGRNDICTN---------------- 763
            |.|     || ||.:.  ..:.|...|...|.|   |.|..|.:.|.:|
Zfish   834 NDP-----SC-RGTVQNGRVEFNFDNDQHICGT---NLVANGSHFIYSNYIVGTPGTEGLISRVR 889

  Fly   764 -IRGSYKCT---TVNCPLGYSIDPEQKNRCRQNLNFCEGEECYTQPSAFTYNFITFVSKLMIPPD 824
             ::.|:.|.   |....:...|:|.|..                            |.|::  |.
Zfish   890 ILKLSFSCVYPQTQTLSMNVEINPLQST----------------------------VHKVL--PS 924

  Fly   825 GRTIFTLRGPLWYDNIEFDLKIV-RIQA----TTNIQKATDGSFDTLQNNNQVNVILKKSLEGP- 883
            |..::.:|...:.|. ||..... |:.|    ..:::...:|     .::.|..:::......|
Zfish   925 GEGVYQVRMVPYVDE-EFTQPFTGRVDAELDQEMHVEVGVEG-----VDSRQFALVMDTCWATPV 983

  Fly   884 QDIELELSMTVYTNGMP-----------RGKSVA-----KLFLFVSQHT 916
            .|.:..|...:.|.|.|           .|.|.:     ::|:|.:..|
Zfish   984 NDPDYSLRWDLITEGCPNPMEGTVKLLQNGISTSSRFSFRMFIFTANST 1032

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31999	NP_726551.2	vWFA	<189..227	CDD:469594	5/37 (14%)
		EGF_CA	251..293	CDD:238011	12/61 (20%)
		EGF_CA	328..>363	CDD:214542	6/42 (14%)
		EGF_CA	421..447	CDD:429571	3/25 (12%)
		EGF_CA	519..564	CDD:214542	13/44 (30%)
		EGF_CA	565..601	CDD:238011	9/39 (23%)
		EGF_CA	611..642	CDD:429571	12/58 (21%)
		FXa_inhibition	661..696	CDD:464251	3/34 (9%)
		EGF_CA	698..>730	CDD:214542	7/31 (23%)
		cEGF	723..744	CDD:463661	6/22 (27%)
zgc:153932	NP_001076476.1	Zona_pellucida	818..1054	CDD:459673	46/260 (18%)