DRSC/TRiP Functional Genomics Resources

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Protein Alignment Crk and csk

DIOPT Version :10

Sequence 1:NP_651908.1 Gene:Crk / 43775 FlyBaseID:FBgn0024811 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_001071067.1 Gene:csk / 556454 ZFINID:ZDB-GENE-061103-493 Length:450 Species:Danio rerio


Alignment Length:86 Identity:32/86 - (37%)
Similarity:48/86 - (55%) Gaps:16/86 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 WYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQIVYRIG 76
            |:.|.::|:.| |.|:...|.|:||||:|.:..|||.|||..|.||.:|         :|:|..|
Zfish    82 WFHGKITREQA-ERLLYPPETGLFLVRESTNYPGDYTLCVSCDGKVEHY---------RIIYHNG 136

  Fly    77 ------DQSFDNLPKLLTFYT 91
                  ::.|:||.:|:..||
Zfish   137 KLSIDEEEYFENLMQLMEHYT 157

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CrkNP_651908.1 SH2_CRK_like 4..108 CDD:198180 32/86 (37%)
SH3_CRK_N 109..163 CDD:212692
SH3_CRK_C 201..257 CDD:212693
cskNP_001071067.1 SH3_CSK 11..67 CDD:212703
SH2_csk_like 78..175 CDD:198190 32/86 (37%)
PTKc_Csk 188..443 CDD:133213
Blue background indicates that the domain is not in the aligned region.

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