DRSC/TRiP Functional Genomics Resources

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Protein Alignment Crk and grapa

DIOPT Version :10

Sequence 1:NP_651908.1 Gene:Crk / 43775 FlyBaseID:FBgn0024811 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_001018409.1 Gene:grapa / 553596 ZFINID:ZDB-GENE-050522-347 Length:214 Species:Danio rerio


Alignment Length:164 Identity:49/164 - (29%)
Similarity:79/164 - (48%) Gaps:22/164 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 NSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQDQIVYR 74
            ::|:.|.:||..| |..:::|:.|.||||:|.|..|::.:.|.....|.::   ||.:..:..|.
Zfish    58 HAWFAGRISRHVA-ENRLHQRDCGSFLVRESESAPGEFSMSVSYGDHVQHF---KVLKDREGYYF 118

  Fly    75 IGDQSFDNLPKLLTFYT-----------LHYLDTTPLKRPACRRVEKVIGKFDFVGSDQDDLPFQ 128
            :.::.|.:|.:|:.||.           |..||.| ||||     ......|||.......|.|.
Zfish   119 VWEEIFPSLNQLVDFYKTNSIAKERTVFLRDLDHT-LKRP-----HHAHALFDFNPEHNSQLHFL 177

  Fly   129 RGEVLTIVRKDEDQWWTARNSSGKIGQIPVPYIQ 162
            ||:|:.::...:.|.|..| ..|::|..|..|:|
Zfish   178 RGDVIDLLDCSDSQRWKGR-CRGRVGFFPPEYVQ 210

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CrkNP_651908.1 SH2_CRK_like 4..108 CDD:198180 33/108 (31%)
SH3_CRK_N 109..163 CDD:212692 16/54 (30%)
SH3_CRK_C 201..257 CDD:212693
grapaNP_001018409.1 SH3 2..55 CDD:473055
SH2_Grb2_like 56..149 CDD:199828 26/94 (28%)
SH3_GRB2_like_C 159..211 CDD:212739 16/53 (30%)
Blue background indicates that the domain is not in the aligned region.

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