Protein Alignment Crk and crk

DIOPT Version :10

• Sequence 1: NP_651908.1
• Gene: Crk / 43775
• FlyBaseID: FBgn0024811
• Length: 271
• Species: Drosophila melanogaster
• Sequence 2: NP_001003628.1
• Gene: crk / 445234
• ZFINID: ZDB-GENE-040801-148
• Length: 311
• Species: Danio rerio
• Alignment Length: 300
• Identity: 137/300 - (45%)
• Similarity: 177/300 - (59%)
• Gaps: 46/300 - (15%)

  Fly     4 FDVSDRNSWYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVREDTKVSNYIINKVQQQ 68
            ||..||.|||:|.:|||:|..:|..:| .||||||||.:|.|||||.|.|::|||:||||.:...
Zfish     5 FDSEDRGSWYWGRLSRQEAVSLLQGQR-HGVFLVRDSITIPGDYVLSVSENSKVSHYIINSISSN 68

  Fly    69 DQI-------VYRIGDQSFDNLPKLLTFYTLHYLDTTPLKRPACR------------------RV 108
            .|.       .:|||||.||.||.||.||.:||||||.|..|..:                  |:
Zfish    69 RQSGPGLAPPRFRIGDQEFDALPALLEFYKIHYLDTTTLIEPISKSKHSSFISVNAGTGGAPPRL 133

  Fly   109 EK--VIGKFDFVGSDQDDLPFQRGEVLTIVRKDEDQWWTARNSSGKIGQIPVPYIQQY------- 164
            |:  |...|||.|:|.:||||::|:||.::.|.|:|||.|:||.|::|.|||||:::|
Zfish   134 EEEYVRALFDFPGNDDEDLPFRKGDVLRVLEKPEEQWWNAQNSEGRVGMIPVPYVEKYRPASPTS 198

  Fly   165 ----------DDYMDEDAIDKNEPSISGSSNVFESTLKRTDLNRKLPAYARVKQSRVPNAYDKTA 219
                      ..:.:.|......|.:.|....:.......:|... |.|||..|.||||||||||
Zfish   199 GAPGVSVSGSGAHGNSDGHSTQSPPLLGEPGQYAQPTSLPNLQNG-PVYARAIQKRVPNAYDKTA 262

  Fly   220 LKLEIGDIIKVTKTNINGQWEGELNGKNGHFPFTHVEFVD 259
            |.||:||::||||.|:|||||||..||:||||||||..:|
Zfish   263 LALEVGDMVKVTKINVNGQWEGECKGKHGHFPFTHVRLLD 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Crk	NP_651908.1	SH2_CRK_like	4..108	CDD:198180	59/128 (46%)
		SH3_CRK_N	109..163	CDD:212692	29/55 (53%)
		SH3_CRK_C	201..257	CDD:212693	42/55 (76%)
crk	NP_001003628.1	SH2_CRK_like	5..115	CDD:198180	59/110 (54%)
		SH3_CRK_N	136..190	CDD:212692	28/53 (53%)
		SH3_CRK_C	244..300	CDD:212693	42/55 (76%)