DRSC/TRiP Functional Genomics Resources

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Protein Alignment Crk and FER

DIOPT Version :10

Sequence 1:NP_651908.1 Gene:Crk / 43775 FlyBaseID:FBgn0024811 Length:271 Species:Drosophila melanogaster
Sequence 2:NP_524288.3 Gene:FER / 41118 FlyBaseID:FBgn0000723 Length:1325 Species:Drosophila melanogaster


Alignment Length:114 Identity:26/114 - (22%)
Similarity:49/114 - (42%) Gaps:39/114 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    12 WYFGPMSRQDATEVLMNERERGVFLVRDSNSIAGDYVLCVR-EDTKV---------SNYIINKVQ 66
            |:.|.:.|::...:|.|:   |.||||::          :| |::::         .::|   ||
  Fly   960 WFHGVLPREEVVRLLNND---GDFLVRET----------IRNEESQIVLSVCWNGHKHFI---VQ 1008

  Fly    67 QQDQIVYRIGDQSFDNLPKLLTFYTLH-YLDTTP--------LKRPACR 106
            ...:..:|.....|.::.:|:    :| |....|        |:||.||
  Fly  1009 TTGEGNFRFEGPPFASIQELI----MHQYHSELPVTVKSGAILRRPVCR 1053

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CrkNP_651908.1 SH2_CRK_like 4..108 CDD:198180 26/114 (23%)
SH3_CRK_N 109..163 CDD:212692
SH3_CRK_C 201..257 CDD:212693
FERNP_524288.3 F-BAR_Fes_Fer 7..243 CDD:153341
SH2_Fps_family 953..1039 CDD:198224 20/98 (20%)
PTKc_Fes_like 1067..1315 CDD:270637
Blue background indicates that the domain is not in the aligned region.

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