DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31998 and Prrt3

DIOPT Version :9

Sequence 1:	NP_726548.1	Gene:	CG31998 / 43774	FlyBaseID:	FBgn0051998	Length:	1459	Species:	Drosophila melanogaster
Sequence 2:	NP_001296392.1	Gene:	Prrt3 / 502873	RGDID:	1562419	Length:	978	Species:	Rattus norvegicus

Alignment Length:	946	Identity:	177/946 - (18%)
Similarity:	297/946 - (31%)	Gaps:	289/946 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 TQRYHSSHQQHGVG-GRPKNYEL-----------------------DLERDHALP----TSAPNA 253
            :.|:..:.|.|..| .||.:..|                       ||:...||.    |..|::
  Rat    60 SSRHSGTPQAHAEGPKRPADSPLGPALHGPKVAPGVVQGERLLRADDLQLARALTSQGWTGPPDS 124

  Fly   254 DILKSNNNPTYPNP-NRHHSHDRDRHRNVVLHSSTPIPSIPNLLKKINGAQPPTIPMYPGDIPSY 317
            ..|.....|. |:| ...|              .|.:|:.|:.  ::..|...|....||.....
  Rat   125 QELLETEAPE-PHPMGAPH--------------LTLVPTTPSF--QLTVATLDTASQKPGGPAGQ 172

  Fly   318 SPP-------SRAFFTPPLPPEYQ-NPFADKP------TL----RGTNNEGLIAVNRRPIPPPSL 364
            .||       .....|..||..|| :|....|      ||    :|.:.:||....:.|     |
  Rat   173 QPPRDEGLMAKAKTHTQALPWGYQGSPHILVPETGAVRTLVLGKQGGHEQGLQEAVQGP-----L 232

  Fly   365 MPSQDRIPIRPPDLGSNNNDAVVNSMTDLNYAPSGMDAKHRLEENFAHGTVSDISGVERIKALNT 429
            :..||.   ..|::||.   ..|.:..::...|.             .||..|     |..|.:.
  Rat   233 LTQQDP---ATPEVGST---PPVEAPVEVKSTPE-------------PGTQLD-----RALARSL 273

  Fly   430 PARASGEEYLYEKASSAKGQG-SYEVDAIGPNKRQ-------------EVLP--------NIRRI 472
            |.    .|.|..:.|...|.| ::||.::||...|             .:.|        ::|..
  Rat   274 PL----PEGLPAEPSKKGGAGDTWEVSSLGPQPEQTDHHGGQDSPAPPPIPPAASDISDGHLRPA 334

  Fly   473 LGSKNGDIPAVLLKHVTQRPIITLRQPPSSPIVLIEKSTSNEEIIDADAPSVVSPNINHSKYHPG 537
            :.|.||..|      ::.:.:....:.|.:|...|....::.:..:.....:.:...:.::..||
  Rat   335 IASMNGVDP------ISPQRVRGAMEAPGTPKSFIPDLLNSAQAANGTESPMRALQPDEAEEWPG 393

  Fly   538 QLEYYENATAGTTPSAAAAIGDVSATSFSYATTNA-GQPGHTGKTTDAIRELGTGVPDQNPIGAA 601
            :.:.:..|.....||.:.. |.|..|     |..| |||.....:..::    ..:|..:|...|
  Rat   394 RPQSHPPAPPVQAPSTSRR-GLVKVT-----TQRALGQPPPPEPSASSM----VPIPASSPPANA 448

  Fly   602 AAATVHTTW-------AWAWNIHIYLSVVLFTILSVYSLYKLLTYNKLTHLFAQAYFVCINLILI 659
            .|..:.  |       :::|.:|:|...|||.:.::.:|..|..      ..|......:..:|:
  Rat   449 TAPPLR--WGPLRRVLSFSWELHVYGVGVLFLLPALLALVTLAA------ALAGPRLALVAAVLV 505

  Fly   660 MICI-LRIFFLCFDAYNVHGSFNLFTSELFLNLPSTFLTVAFSVLILFLFLKSLNHKNNRYSALI 723
            ::.. ||..::..|.|.......:....:..|||...|..|.:.|.|......|.      ..|.
  Rat   506 LVASGLRSAYMLTDPYGSQARLGVRAGLVLYNLPFPLLLTALAALTLLGLGAGLP------QPLQ 564

  Fly   724 RPLTVVVGCGVHVVLCITLHYVESYTLKNHHLYFQQQQQQQYFRRQQLYNQQGQPTATMSPSAIL 788
            :||.:.|...||                                           .|.:..:.:.
  Rat   565 KPLLLGVVAPVH-------------------------------------------GAGLLATDLF 586

  Fly   789 PPPPRVLTLICQIIYIFICLSLGLLYLYIYRILKRILRSKSQNYIHGYQNLSYAIHITIATALLF 853
            ...| ||.|:.|.:......|:.|..|.:.|  :|:|...     .|: :.|....:......|.
  Rat   587 STSP-VLNLLTQGLSCAWGASVALGTLCLCR--RRLLEGP-----RGW-DASPGPRLLAVAGSLG 642

  Fly   854 VLLAALQIFGAIYISCRHTSIVDVDWLQWGYQFSLRLIE------IAIITLMS-----------W 901
            :|.:.||:..::::...........|..||..|.|||:|      :|:..|.:           |
  Rat   643 LLASGLQLAASLWLYPGPGREGRFSWAWWGVHFWLRLLELTWALALALAALAATRPRPPTEHACW 707

  Fly   902 VAGL---------KTSVEHDSLSAVAGDVRMIGSGMGAYGQDGGTPNNAIREKHVGNGTGTHNSN 957
            ...|         |:.|.....:..||.     ||:|..|.|       |.:..:.|..|.....
  Rat   708 AKLLRLACPAPTGKSEVPERPNNCYAGP-----SGVGTGGLD-------ISKSLIRNAAGEGGLP 760

  Fly   958 VTNFFLPCTSSSSQEHFETDYPAVCNANTNLHTYTMRTGKLIYDDSYALNSMGPTTATTSNARPC 1022
            .|....|..|::|........|.:                       :..|:||..:.:
  Rat   761 ATPGSGPWGSAASLGRGRPGGPGM-----------------------SRGSVGPAPSLS------ 796

  Fly  1023 EYQLQEPMYQRPYDTGSIGSTLNQQHQLNQMRFQEH 1058
            |..|:.|            |.:|....::...|:||
  Rat   797 ELDLRPP------------SPINLSRSIDAALFREH 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31998	NP_726548.1	EXS	610..>724	CDD:296120	24/121 (20%)
Prrt3	NP_001296392.1	PHA03247	<64..468	CDD:223021	91/471 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28K70
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900