Protein Alignment CG31998 and PRRT3

DIOPT Version :10

• Sequence 1: NP_726548.1
• Gene: CG31998 / 43774
• FlyBaseID: FBgn0051998
• Length: 1459
• Species: Drosophila melanogaster
• Sequence 2: NP_997234.3
• Gene: PRRT3 / 285368
• HGNCID: 26591
• Length: 981
• Species: Homo sapiens
• Alignment Length: 780
• Identity: 157/780 - (20%)
• Similarity: 250/780 - (32%)
• Gaps: 209/780 - (26%)

  Fly   223 SHQQHGVGGRPKNYELDLERDHALPTSAPNADILKSNNNPTYPNPNRHHSHDRDRHRNVVLHSST 287
            :|.:..||..|:.:                 |:...|     |..:.|.:.| .||.........
Human    45 AHPKGSVGSEPQAF-----------------DVFPEN-----PRADSHRNSD-VRHAPAEEMPEK 86

  Fly   288 PI--PSIPNLL--KKINGAQPPTIPMYPGDIPSYSPPSRAFFTPPLPPE---YQNPFADKPT--- 342
            |:  |..|.|.  |...|||...:|: ..|:.....||...:|.||..:   .|...|..|.
Human    87 PVASPLGPALYGPKAAQGAQRERLPV-TDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHP 150

  Fly   343 ------------LR-----------------GTNNEGLIAVNRRPIPPPSLMPSQDRIPIRPPDL 378
                        ||                 ...:|||.|..:..:||.|  ||..:   .||..
Human   151 HLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTS--PSDHQ---GPPHT 210

  Fly   379 GSNNNDAVVNSMTD--------LNYAPSGMDAKHRLEENFAHGTVSDISGVERIKALNTPARAS- 434
            ..:::..|...:.:        |..|..|   .|..:::.|...|..:..||.:.:....|:..
Human   211 LVSHSGTVKRPVLEGQGGFEEHLQEAAQG---PHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDL 272

  Fly   435 --------GEEYLYEKASSAKGQGSYEVDAIGPNKRQEVLPNIRRILGSKNGDIPAVLLKHVTQR 491
                    .||...|....|..:.|:||.:.||..:|..||:.:...|.:..|.||   .....|
Human   273 ALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPA---SEAPDR 334

  Fly   492 PIITLR-----QPPSSPIVL---IEKSTSNEEIIDADAPSVVSPNINHSK-----YHPGQLEYYE 543
            |....|     ..|.||..:   :|...:.:.:|  ..||...|.:|.::     ..|.:.|.:.
Human   335 PSKPERAAMNGADPISPQRVRGAVEAPGTPKSLI--PGPSDPGPAVNRTESPMGALQPDEAEEWP 397

  Fly   544 NATAGTTPSAAAAIGDVSATSFSYATTN--AGQPGHTGKTTDAIRELGTGVPDQNPIGAAAAATV 606
            .......|:........|.......||.  .|||.....|..::    ...|..:|...|.|..:
Human   398 GRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSM----ASAPASSPPANATAPPL 458

  Fly   607 HTTW-------AWAWNIHIYLSVVLFTILSVYSLYKLLTYNKLTHLFAQAYFVCINLILIMIC-I 663
            .  |       :::|.:|:|...|||.      |..||....|....|......:..:|:::. .
Human   459 R--WGPLRRVLSFSWELHVYGVGVLFL------LPALLALAALAAAPAGPRLALVAAVLVLVASA 515

  Fly   664 LRIFFLCFDAYNVHGSFNLFTSELFLNLPSTFLTVAFSVLILFLFLKSLNHKNNRYSALIRPLTV 728
            ||..::..|.|.......:....:..|||...|..|.:.|.|......|.      ..|..||.:
Human   516 LRSAYMLTDPYGSQARLGVRGGLVLYNLPFPLLLTALAALTLLGLGAGLP------PPLQNPLLL 574

  Fly   729 VVGCGVHVVLCITLHYVESYTLKNHHLYFQQQQQQQYFRRQQLYNQQGQPTATMSPSAILPPPPR 793
            .....||.|..:....:.:::
Human   575 GAVALVHGVGLLATDLLSTWS-------------------------------------------- 595

  Fly   794 VLTLICQIIYIFIC-----LSLGLLYLYIYRILKRILRSKSQNYIHGYQNLSYAIHITIATALLF 853
            ||.|:.|.:   .|     ::||.|.|...|:|         :...|: :.|....:......|.
Human   596 VLNLLTQGL---SCAWGAAVALGTLCLCRRRLL---------DGPRGW-DASPGPRLLAVAGALG 647

  Fly   854 VLLAALQIFGAIYISCRHTSIVDVDWLQWGYQFSLRLIEIAIITLMSWVAGLKTSVEHDSLSAVA 918
            :|.:.||:..|:::......:....|..||..|.|||:|      ::|...|       :|:|||
Human   648 LLASGLQLAAALWLYPGPGRVGRFSWAWWGVHFWLRLLE------LTWALAL-------ALAAVA 699

  Fly   919  918
            Human   700  699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31998	NP_726548.1	None
PRRT3	NP_997234.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..107		18/84 (21%)
		PHA03247	<84..468	CDD:223021	84/403 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..457		63/304 (21%)
		O-glycosylated at one site	297..302		3/4 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	759..807
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	836..865
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	937..981