DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ABCD and ABCD2

DIOPT Version :9

Sequence 1:	NP_001245409.1	Gene:	ABCD / 43772	FlyBaseID:	FBgn0039890	Length:	730	Species:	Drosophila melanogaster
Sequence 2:	NP_175837.2	Gene:	ABCD2 / 841876	AraportID:	AT1G54350	Length:	706	Species:	Arabidopsis thaliana

Alignment Length:	774	Identity:	192/774 - (24%)
Similarity:	317/774 - (40%)	Gaps:	159/774 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ILALTIKVTIPYVKNVNTTSSVRTQKGKTNGQLSPSTRDSSEEDFKLAEAEKLLVAQQLKKKATN 98
            ||.:|..|..|::. :..:|.:|.:....|.....:.|      |:......||....::....:
plant     2 ILMITAPVCPPHLL-LRHSSLLRHESSIGNFHRKKNPR------FRTVSCSSLLPQPSVRPDKAS 59

  Fly    99 NLVEPGLNKEFLKHLQMLAKIMIPQAFCY---ETGLLSVHTFCL-ISRTFLSIYVAALEGALVKF 159
            .|  ..|.|:|.       |:..|..|..   :..|.....|.| ::.|.:|:....|.......
plant    60 EL--KTLWKKFY-------KVASPYWFSEDKDQARLRLAAVFALTLATTGISVGFNFLGRDFYNS 115

  Fly   160 IVRKDIKQFALVLLKW---FGIAIPATFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYRV 221
            :..||.:||...|..:   |...||...:..   :.:..|||.:|:.:.::..:.|.|:|.:|::
plant   116 LANKDQEQFTKQLFYYLCAFAGGIPFFVLRD---YTKETLSLRWRSWMTKYYLQRYLKDQTFYKI 177

  Fly   222 SNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGLALMRSSKKMKANII--TGPAL 284
            .: ...|:|.|.||.:|:|.|..:......:|.....||:..            :||:  ..|.|
plant   178 QS-QSIIDNPDQRLVDDLSSFTGTALSFSLTLVNATIDLISF------------SNILFTIYPPL 229

  Fly   285 -------SIGVIALTAHILR-IVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEM 341
                   |.|..|::..:.: :|:..|.|...|...||..:     |:..|||.||||||.:.||
plant   230 FLVLLLYSFGGTAISVFLGKGLVNLNFLQEKKEADFRYSLV-----RVRENAESIAFYGGEQNEM 289

  Fly   342 QQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILT------GSDVGLGTV 400
            |.|.|.:....:.:|.        :::....:::...|...::..||:..      ...:..|.:
plant   290 QLLLQRFRSAFDNLTE--------LLIASRNLEFFTDGYRYLIQILPVAVVAPMYFSGKIEFGVI 346

  Fly   401 PNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAG--------YTFRVAGMMDV 457
             |.::|      ...::....:|::....||    ||:..::...|        ..||  ...|.
plant   347 -NQSVS------AFNHILGDFSLVVYQFQAI----SSFSAVIDRLGEFDDLLDNNIFR--DPSDT 398

  Fly   458 FEETALGVYCKTSVMESNQS----NGIIEFRNGKPIAKGRIIYSDDPKNMSISLRAVPVVTP-NC 517
            .:|..|     |...|.|.|    ||.|:               ..|....:.:..:.:.|| |.
plant   399 VDEIEL-----TYQSEMNSSLLDTNGSIK---------------SQPNQKRLEIEELTLQTPTNG 443

  Fly   518 DIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAG--------ELHIPRPVKDVP-- 572
            ..:|..|:..:....||||.||:|.||:||.|.::|||....|        |:...:...|..
plant   444 TTLVHNLSADVYDKDHLLIMGPSGSGKTSLLRAMAGLWRSGKGKITFYLDPEVDFTQEKSDTQEN 508

  Fly   573 -----CMFYIPQRPYMSIGSLCDQIIYPD----------------------TREDMKRKHITENE 610
                 .:.::||||||.:|||..|::||.                      .|||...|..|::.
plant   509 SGKRGDVLFLPQRPYMVLGSLRQQLLYPTWSATVEETTPGGSNIDGSPPLLIREDGNEKPTTDDL 573

  Fly   611 LRSILKMVSLEHIAQR-DSFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVE 674
            :|: |:.|.|.|||.| ...|.:.:|..:||.||:||:|.|||...:|:.|||||.|||:....|
plant   574 MRT-LEKVCLGHIADRFGGLDSIHEWSSVLSLGEQQRLAFARLLLSQPKLALLDESTSALDEANE 637

  Fly   675 SSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLG------NWQFRKMNSDEEQKGQ 727
            :.:|:..:..|||.::|.||.||.|:|..||:.....      ||:...:::.:...|:
plant   638 AFLYQQIQSAGITYISIGHRRTLTKFHNKILQISTADPKSNERNWRIEDVDAQDSLYGR 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ABCD	NP_001245409.1	3a01203	75..715	CDD:273360	182/719 (25%)
ABCD2	NP_175837.2	YddA	58..670	CDD:226646	177/683 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	175	1.000	Inparanoid score	I1498
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D309052at2759
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.860