Protein Alignment ABCD and pmp-2

DIOPT Version :9

• Sequence 1: NP_001245409.1
• Gene: ABCD / 43772
• FlyBaseID: FBgn0039890
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_495408.1
• Gene: pmp-2 / 174127
• WormBaseID: WBGene00004059
• Length: 661
• Species: Caenorhabditis elegans
• Alignment Length: 663
• Identity: 233/663 - (35%)
• Similarity: 372/663 - (56%)
• Gaps: 67/663 - (10%)

  Fly    85 KLLVAQQLKKKATNNLVEPGLNKEFLKHLQMLAKIMIPQAFCYETGLLSVHTFCLISRTFLSIYV 149
            |.|||:  .||..:...:..::..||..|..:.||:||..|..|:..|.:....|:.||:..:|:
 Worm    44 KHLVAK--TKKDGSKGQKAHVDGVFLGKLARILKILIPGFFSKESFYLILIAVSLLCRTYADVYM 106

  Fly   150 AALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFV-NSMIRFLESKLSLAFRTRLVRHSYRLYF 213
            ......:...|:.::...|||...|:. :.:||..| |::::|..::|.|.||.||..|.|..|.
 Worm   107 IITSTKIEASIIDRNPLLFALEAFKYV-LNLPAISVTNAILKFGIAELKLRFRERLSTHLYSQYL 170

  Fly   214 KNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLML----IGLALMRSSKKM 274
            |...:|::||||.||:|||..||:|:..|.:.:..|||:|:||..|:.|    :|.:|..||
 Worm   171 KGFTFYKMSNLDTRIQNADQLLTQDVDRFCDGIVELYSNLSKPILDVFLYLFRLGTSLGFSS--- 232

  Fly   275 KANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKV 339
                   |::....:..|...|..:....|:|..||....|..|:::||:|.|:||||||.|::.
 Worm   233 -------PSILFSYLLFTGVGLTYLRRPIGRLTVEEQALEGEYRYVNSRLIMNSEEIAFYQGNQS 290

  Fly   340 EMQQLRQAYNRLVNQMTTI--FNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSD-------- 394
            |.:.:...:..||..:..|  |...:.|:  :....||:.:..|...|      ||.
 Worm   291 EKETIMSTFASLVQHLRKIILFRFSIGFV--DNIVAKYLATVVGWYAV------GSSFFDKQHKP 347

  Fly   395 -VGLGTVPNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVF 458
             :|:          ||.....:|..:.| ::...|:|:.||..:.:::..|:|:|.||..:::|.
 Worm   348 FIGM----------SRNQLMQEYYNSGR-MMYKMAEALGRLALAGRDMTRLSGFTSRVDTLLNVL 401

  Fly   459 EETALGVYCKTSVMESNQSNGIIEFR----NGKPIAKGRIIYSDDPKNMSISLRAVPVVTPNCDI 519
            ::...|.|.:|.|.|..:|:.:|:..    :|....:..:|..|:          ||:||||.|:
 Worm   402 DDVNSGNYKRTMVGEKEESSALIKSELVAGSGNLRVQDNVIRFDN----------VPLVTPNGDV 456

  Fly   520 VVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVPCMFYIPQRPYMS 584
            ::.:|...:..|.::|:.||||||||||||:|..|||::.|.|..|...|    :||:||||||:
 Worm   457 LIERLNFEVPSGTNVLVCGPNGCGKSSLFRVLGELWPLFGGTLTKPAKGK----LFYVPQRPYMT 517

  Fly   585 IGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWKDILSGGEKQRMA 648
            :|:|.|||||||...||.||.:::::|..:|:.|.|.||.:|: .:..|:||.|:||||||||:|
 Worm   518 LGTLRDQIIYPDRPLDMIRKGVSDSDLEQMLENVQLTHILEREGGWSAVQDWMDVLSGGEKQRIA 582

  Fly   649 IARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNW 713
            :||||||:|::|:|||||||||:|||.::|.:.:...|||.|::||.:|||||.:.|..||.|::
 Worm   583 MARLFYHKPQFAILDECTSAVSVDVEGAMYRLCREKNITLFTVSHRKSLWKYHEYSLYMDGRGSY 647

  Fly   714 QFRKMNSDEEQKG 726
            :|.:::...:|.|
 Worm   648 RFEQIDDQSDQFG 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCD	NP_001245409.1	3a01203	75..715	CDD:273360	230/650 (35%)
pmp-2	NP_495408.1	3a01203	1..649	CDD:273360	230/650 (35%)
		ABC_membrane_2	62..341	CDD:284003	92/297 (31%)
		ABCD_peroxisomal_ALDP	442..647	CDD:213190	109/218 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53776
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730