Protein Alignment ABCD and pmp-1

DIOPT Version :9

• Sequence 1: NP_001245409.1
• Gene: ABCD / 43772
• FlyBaseID: FBgn0039890
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: NP_495407.1
• Gene: pmp-1 / 174126
• WormBaseID: WBGene00004058
• Length: 665
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 237/646 - (36%)
• Similarity: 372/646 - (57%)
• Gaps: 50/646 - (7%)

  Fly    92 LKKKATNNLVEPGLNKEFLKHLQMLAKIMIPQAFCYETGLLSVHTFCLISRTFLSIYVAALEGAL 156
            :||..|    :..||.||...|:.|.||:||..|..|...:.|..|.|::||...:|:.....::
 Worm    58 VKKGKT----KASLNAEFFAKLKKLLKILIPGPFSSEVFYMIVIGFVLLARTIADVYMITNATSV 118

  Fly   157 VKFIVRKDIKQFALVLLKWFGIAIPA-TFVNSMIRFLESKLSLAFRTRLVRHSYRLYFKNQNYYR 220
            ...||.:....||:.:.|:| :.:|| :.:|::::|..|:|.|.||..|.::.|..|.....||:
 Worm   119 EASIVDRSPIMFAMSVFKYF-LNLPAISLINALLKFSLSELKLRFRENLTKYLYGKYLGGFTYYQ 182

  Fly   221 VSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLML----IGLALMRSSKKMKANIITG 281
            :||||.||:|.|..||:|:..|.:.:..|||::|||..|:.|    :|.||...          |
 Worm   183 ISNLDSRIQNPDQLLTQDVEKFCDGIVELYSNMTKPILDVFLYVFKLGRALGWE----------G 237

  Fly   282 PALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAEEIAFYGGHKVEMQQLRQ 346
            |.|..|.:..:..:|..:.....:|..||....|..|:::||:|.|:||||||.|:|.|.|.|..
 Worm   238 PGLLFGYLMASMVVLTKLRRPIAKLTVEEQVLEGEYRYVNSRLIMNSEEIAFYQGNKPEKQALMG 302

  Fly   347 AYNRLVNQM--TTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTGSDVGLGTVPNTAISESR 409
            ::|.||..:  |.:|...|.|:  :....||:.:..|.:..:   .|..||.     |...:|..
 Worm   303 SFNNLVYHLRKTIMFRFTLGFV--DNIVGKYITNIVGWVACA---KTFFDVN-----NEKFNEMD 357

  Fly   410 VSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGMMDVFEETALGVYCKTSVMES 474
            .:|..|.|.....:::..::|:.||..:.:::..|:|:|.||..:|.|.::...|.:.|..|.:.
 Worm   358 RNELMQELYNNGRMMLKLSEALGRLALAGRDMTRLSGFTTRVDTLMKVLDDMKAGRFEKAQVADE 422

  Fly   475 NQSNG---IIEFRNGKPIAKGRIIYSDDPKNMSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLI 536
            :...|   :::..:||.:|:..:|..|:          ||:||||.||::..|:..:..|.::|:
 Worm   423 SGEEGQRLMLKAGSGKLLAQDNMIKFDE----------VPLVTPNGDILIESLSFEVPSGRNVLV 477

  Fly   537 TGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVPCMFYIPQRPYMSIGSLCDQIIYPDTREDM 601
            .||||||||||||.|..|||:..|.|..|...|    :||:||||||::|:|.||:|||||..||
 Worm   478 CGPNGCGKSSLFRTLGELWPVMGGTLTKPAKGK----LFYVPQRPYMTLGTLRDQVIYPDTSFDM 538

  Fly   602 KRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWKDILSGGEKQRMAIARLFYHRPRYALLDEC 665
            |.|.:::.:|..:|:.|.|.:|.:|: .:..|:||.|:||||||||:|:||||||:|::|:||||
 Worm   539 KMKGMSDKDLEQMLENVQLTNILEREGGWSAVQDWMDVLSGGEKQRIAMARLFYHKPQFAILDEC 603

  Fly   666 TSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYHTHILEFDGLGNWQFRKMNSDEEQKG 726
            |||||:|||.::|.:.:.|.|||.|::||.:|||||.:.|..||.|:::|.:::...:|.|
 Worm   604 TSAVSVDVEGAMYRLCREMNITLFTVSHRKSLWKYHEYSLYMDGRGSYRFEQIDDQSDQFG 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABCD	NP_001245409.1	3a01203	75..715	CDD:273360	234/633 (37%)
pmp-1	NP_495407.1	3a01203	1..653	CDD:273360	234/633 (37%)
		ABC_membrane_2	67..346	CDD:284003	97/294 (33%)
		ABCD_peroxisomal_ALDP	446..651	CDD:213190	110/218 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4178
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53776
OrthoDB	1	1.010	-	-		D146647at33208
OrthoFinder	1	1.000	-	-		FOG0000393
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X313
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730