Protein Alignment Abcd1 and Pmp70

DIOPT Version :10

• Sequence 1: NP_651906.1
• Gene: Abcd1 / 43772
• FlyBaseID: FBgn0039890
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: XP_310656.2
• Gene: Pmp70 / 1271802
• VectorBaseID: AGAMI1_007811
• Length: 659
• Species: Anopheles gambiae
• Alignment Length: 680
• Identity: 242/680 - (35%)
• Similarity: 382/680 - (56%)
• Gaps: 72/680 - (10%)

  Fly    65 QLSPSTRDSSEEDFKLAEAEKLLVAQQLKKKATNNLVEPGLNKEFLKHLQMLAKIMIPQAFCYET 129
            |:..:.:...|::.      :.|::.:.:|::.    :..:|..|...|:.|..|:||:.:..|.
Mosquito    33 QIHKNRKQRPEDEI------QYLISDKKEKRSP----KAHVNAVFFNQLRTLLGIIIPKKWSVEN 87

  Fly   130 GLLSVHTFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPA-TFVNSMIRFLE 193
            |||.|....||:|:...|::.....|:...|:..:.|||...|:|:.. |:|| ..||:::::..
Mosquito    88 GLLVVIALSLIARSVSDIWMIQNATAIESTIITMNKKQFRTALVKYLS-ALPAIAVVNNVLKWSI 151

  Fly   194 SKLSLAFRTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCF 258
            .:|.|.|||.|.::.|..|.|...||::||||.||.|||..||.||..|..||..|||::.||..
Mosquito   152 GELKLRFRTNLSQYLYNEYLKGFTYYKMSNLDNRIANADQLLTTDIDKFCESVTDLYSNICKPLL 216

  Fly   259 DLMLIGLALMRSSKKMKANIITGPALSIGVIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSR 323
            |:::.   :.|.:..:..   |.|.:.:..:..:...|..:....|:|...|....|..|:::||
Mosquito   217 DIVIY---VYRLTTNLGG---TTPGILLLYLFFSGVFLTNLRKPTGRLTVLEQKLEGEFRYVNSR 275

  Fly   324 IITNAEEIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSL- 387
            :|||:||||||.|:..|...:..::|:||..:......::...:::....||:.:..|...|||
Mosquito   276 LITNSEEIAFYKGNNREKLTILASFNKLVGHLRKFLEFRVGMGIVDNMVAKYIATVVGFYAVSLP 340

  Fly   388 ------PILTGSDVGLGTVPNTAISESRVSER-TQYLTTARNLLISAADAIERLMSSYKEIVSLA 445
                  |:|||               |:.||| ::|.|..| :|:..|:||.||:.:.:|:..||
Mosquito   341 FFEKDHPLLTG---------------SQQSERLSRYYTFGR-MLVKLAEAIGRLVLAGREMSRLA 389

  Fly   446 GYTFRVAGMMDVFEETALGVYCKTSVMES--------NQSNGIIEFRNGKPIAKGRIIYSDDPKN 502
            |:|.|:..:..|.::...|.|.:|.|..|        ....|:::|::                |
Mosquito   390 GFTARMTELTVVLKDLNSGRYERTMVNNSAIADAGDIGPGRGLLKFQD----------------N 438

  Fly   503 MSISLRAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRP 567
            : |....||:||||.|::|..||..::.|:::|:.||||||||||||||..|||.:.|::..|..
Mosquito   439 L-IKFEHVPLVTPNGDVLVKDLTFEVKSGMNVLVCGPNGCGKSSLFRILGELWPTWGGKVTKPPA 502

  Fly   568 VKDVPCMFYIPQRPYMSIGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDV 631
            .|    :|||||||||::|||.||||||.|.::|||:..|:.:|...|.:|.|.::..|: ..|.
Mosquito   503 GK----LFYIPQRPYMTLGSLRDQIIYPHTHQEMKRRGKTDADLLKYLDLVQLTYLQVREKGLDA 563

  Fly   632 VRDWKDILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPT 696
            :.||.|:||||||||:|:||||||.|::|:|||||||||:|||.|:|:..:.:||||.|::||.:
Mosquito   564 IEDWIDVLSGGEKQRIAMARLFYHNPQFAILDECTSAVSVDVEGSMYQYCRAVGITLFTVSHRKS 628

  Fly   697 LWKYHTHILEFDGLGNWQFRKMNSDEEQKG 726
            ||.:|.:.|:|||.|.::|..:...::|.|
Mosquito   629 LWTHHDYYLKFDGHGAYEFGPIEGTQDQFG 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abcd1	NP_651906.1	3a01203	75..715	CDD:273360	238/657 (36%)
Pmp70	XP_310656.2	3a01203	34..647	CDD:273360	238/666 (36%)