Protein Alignment Abcd1 and abcd2

DIOPT Version :10

• Sequence 1: NP_651906.1
• Gene: Abcd1 / 43772
• FlyBaseID: FBgn0039890
• Length: 730
• Species: Drosophila melanogaster
• Sequence 2: XP_004913059.1
• Gene: abcd2 / 101730598
• XenbaseID: XB-GENE-6467268
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 681
• Identity: 354/681 - (51%)
• Similarity: 465/681 - (68%)
• Gaps: 57/681 - (8%)

  Fly    71 RDSSEEDFKLAEAEKLLVAQQLKKKATNNLVEPGLNKEFLKHLQMLAKIMIPQAFCYETGLLSVH 135
            ::|....:|.|..:        ..|.:.....|.:|.||.:.|..|.:|:.|:....|.||||||
 Frog    46 KESDSSPYKQAPCD--------PSKGSPKPSSPAVNAEFYRQLLELRRILFPKLLSKELGLLSVH 102

  Fly   136 TFCLISRTFLSIYVAALEGALVKFIVRKDIKQFALVLLKWFGIAIPATFVNSMIRFLESKLSLAF 200
            :..||||||||:|||.|:|.:||.||.|..:.|.:.|:||..||||||||||.||:||.||:||.
 Frog   103 SLALISRTFLSVYVAGLDGKIVKSIVEKKPRNFLMQLMKWLLIAIPATFVNSAIRYLEGKLALAL 167

  Fly   201 RTRLVRHSYRLYFKNQNYYRVSNLDGRIENADHRLTEDISVFANSVAHLYSSLTKPCFDLMLIGL 265
            |||||.|:||.||.:|.||::.|:|.|:.|.|..|||||.:|:.|||||||:||||..|::|...
 Frog   168 RTRLVDHAYRTYFADQTYYKIINMDSRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVVLTSY 232

  Fly   266 ALMRSSKKMKANIITGPALSIG-VIALTAHILRIVSPKFGQLVSEEANRYGYLRHIHSRIITNAE 329
            .|:::::...||.: ||.|..| |:..||.:|:..|||||:||:|||:|.||||::|||||.|.|
 Frog   233 TLIQTARSRGANPL-GPTLLAGLVVYATAKVLKACSPKFGKLVAEEAHRKGYLRYVHSRIIANVE 296

  Fly   330 EIAFYGGHKVEMQQLRQAYNRLVNQMTTIFNQKLWFIMLEQFFMKYVWSGTGMIMVSLPILTG-- 392
            |||||.||||||.:|:::|..|.:|:..|.:::||::|:|||.|||||||:|::||::||:|.
 Frog   297 EIAFYRGHKVEMTKLQKSYMALADQINLILSKRLWYVMIEQFLMKYVWSGSGLVMVAVPIITATG 361

  Fly   393 ---SDVGLGTVPNTAISESRVSERTQYLTTARNLLISAADAIERLMSSYKEIVSLAGYTFRVAGM 454
               ||:..|.      .::.|||||:..|||||||.|.||||||:||||||:..|||||.||..|
 Frog   362 FADSDLEDGQ------KQAMVSERTEAFTTARNLLASGADAIERIMSSYKEVTELAGYTARVYNM 420

  Fly   455 MDVFEETALGVYCKTSVMESNQSN------------GIIEFRNGKPIAKGRIIYSDDPKNMSISL 507
            ..||.|...|:| |.|:::..::|            |.:|.       ||:::..|.    .|..
 Frog   421 FSVFNEVKKGIY-KRSLIQETKNNKKHKEKTELHIDGPLEI-------KGKVVDVDH----GIIC 473

  Fly   508 RAVPVVTPNCDIVVPKLTLCIEPGVHLLITGPNGCGKSSLFRILSGLWPIYAGELHIPRPVKDVP 572
            ..||::|||.|:||.||.:.:|.|:|||||||||||||||||||.||||:|.|.|:.|.|.|
 Frog   474 EDVPIITPNGDVVVSKLNIKVEEGMHLLITGPNGCGKSSLFRILGGLWPVYEGVLYKPPPQK--- 535

  Fly   573 CMFYIPQRPYMSIGSLCDQIIYPDTREDMKRKHITENELRSILKMVSLEHIAQRD-SFDVVRDWK 636
             |||||||||||||:|.||:||||..|||..|...:.:|..||.:|.|.||.||: .:|...|||
 Frog   536 -MFYIPQRPYMSIGTLRDQVIYPDLLEDMHEKGYQDQDLEHILDIVHLNHIVQREGGWDAFTDWK 599

  Fly   637 DILSGGEKQRMAIARLFYHRPRYALLDECTSAVSIDVESSIYEIAKGMGITLLTITHRPTLWKYH 701
            |:|||||||||.:||:|||||:||||||||||||||||..|::.||..||:||:|||||:|||||
 Frog   600 DVLSGGEKQRMGMARMFYHRPQYALLDECTSAVSIDVEGKIFQAAKDAGISLLSITHRPSLWKYH 664

  Fly   702 THILEFDGLGNWQFRKMN-------SDEEQK 725
            ||:|:|||.|.|:|.:::       |:|:|:
 Frog   665 THLLQFDGEGGWRFEQLDTATRLSLSEEKQR 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Abcd1	NP_651906.1	3a01203	75..715	CDD:273360	349/658 (53%)
abcd2	XP_004913059.1	3a01203	26..678	CDD:273360	350/662 (53%)