DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl4 and Trim23

DIOPT Version :9

Sequence 1:	NP_001245408.1	Gene:	Arl4 / 43771	FlyBaseID:	FBgn0039889	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001348467.1	Gene:	Trim23 / 81003	MGIID:	1933161	Length:	574	Species:	Mus musculus

Alignment Length:	136	Identity:	60/136 - (44%)
Similarity:	86/136 - (63%)	Gaps:	5/136 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LHVVMLGLDSAGKTTALYRLKFDQYLNTVPTIGFNCEKVQCTLGKAKGVHFLVWDVGGQEKLRPL 90
            :.||.||||.|||||.|::||.|:::..:||||||.|.|:     .|.:.|.:|||||:.|||||
Mouse   405 IRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVE-----YKNLKFTIWDVGGKHKLRPL 464

  Fly    91 WRSYTRCTDGILFVIDSVDTERMEEAKMELMRTAKCPDNQGVPVLILANKQDLPNACGAMELEKL 155
            |:.|...|..::||:||...:|:.||..||.:.....:.:...:||.|||||:..|....|:.:|
Mouse   465 WKHYYLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITEL 529

  Fly   156 LGLNEL 161
            |.|::|
Mouse   530 LSLHKL 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl4	NP_001245408.1	P-loop_NTPase	24..311	CDD:304359	60/136 (44%)
Trim23	NP_001348467.1	mRING-HC-C3HC3D_TRIM23_C-IX	28..77	CDD:319559
		modified RING-HC finger (C3HC3D-type)	31..75	CDD:319559
		BBOX	125..168	CDD:237988
		BBOX	173..219	CDD:197662
		ClassIIa_HDAC_Gln-rich-N	226..370	CDD:330228
		ARF-like	390..574		60/136 (44%)
		ARD1	406..574	CDD:206723	60/135 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000