DRSC/TRiP Functional Genomics Resources

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Protein Alignment Arl4 and ARL5B

DIOPT Version :9

Sequence 1:NP_001245408.1 Gene:Arl4 / 43771 FlyBaseID:FBgn0039889 Length:313 Species:Drosophila melanogaster
Sequence 2:NP_848930.1 Gene:ARL5B / 221079 HGNCID:23052 Length:179 Species:Homo sapiens


Alignment Length:266 Identity:73/266 - (27%)
Similarity:101/266 - (37%) Gaps:114/266 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 VVMLGLDSAGKTTALYRLKFDQYLNTVPTIGFNCEKVQCTLGKAKGVHFLVWDVGGQEKLRPLWR 92
            |:::|||:|||||.||:...::.::|.||||.|.|::     ..|..|||:||:||||.||..|.
Human    19 VIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEI-----VVKNTHFLMWDIGGQESLRSSWN 78

  Fly    93 SYTRCTDGILFVIDSVDTERMEEAKMELMRTAKCPDNQGVPVLILANKQDLPNACGAMELEKLLG 157
            :|...|:.|:.|:||:|.||:...|.||.|.....|.:...|||.|||||:.....|.|:.|.|.
Human    79 TYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAAVLIFANKQDMKGCMTAAEISKYLT 143

  Fly   158 LNELYNPVPNISMPSSSDSSPTINLIGCRVSNQSITDKSLEEKKESHLHSSMIHIKPALESKDHN 222
            |:.:                                                         ||| 
Human   144 LSSI---------------------------------------------------------KDH- 150

  Fly   223 STLSGGALTAFIYPQSHNNSAVLDQKNPQDVKNGFHNKKMNRSSSNSVQFRGWYIQPTCAITGEG 287
                                                               .|:||..||:||||
Human   151 ---------------------------------------------------PWHIQSCCALTGEG 164

  Fly   288 LQEGLD 293
            |.:||:
Human   165 LCQGLE 170

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Arl4NP_001245408.1 P-loop_NTPase 24..311 CDD:304359 73/266 (27%)
ARL5BNP_848930.1 Arl5_Arl8 3..175 CDD:133353 73/266 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0070
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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