DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Arl4 and Arl4a

DIOPT Version :9

Sequence 1:	NP_001245408.1	Gene:	Arl4 / 43771	FlyBaseID:	FBgn0039889	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_001034604.1	Gene:	Arl4a / 11861	MGIID:	99437	Length:	200	Species:	Mus musculus

Alignment Length:	298	Identity:	121/298 - (40%)
Similarity:	155/298 - (52%)	Gaps:	109/298 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NILDALPSQVATLHVVMLGLDSAGKTTALYRLKFDQYLNTVPTIGFNCEKVQCTLGKAKGVHFLV 78
            :||.:||| ..:.|:|:||||.|||||.||||:|::::|||||.|||.||::.|||.:|.|.|..
Mouse    10 SILSSLPS-FQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIKVTLGNSKTVTFHF 73

  Fly    79 WDVGGQEKLRPLWRSYTRCTDGILFVIDSVDTERMEEAKMELMRTAKCPDNQGVPVLILANKQDL 143
            |||||||||||||:|||||||||:||:||||.|||||||.||.:..:..:||||||||:||||||
Mouse    74 WDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITRISENQGVPVLIVANKQDL 138

  Fly   144 PNACGAMELEKLLGLNELYNPVPNISMPSSSDSSPTINLIGCRVSNQSITDKSLEEKKESHLHSS 208
            .|:....|:||||.:.||            |.|:|
Mouse   139 RNSLSLSEIEKLLAMGEL------------SSSTP------------------------------ 161

  Fly   209 MIHIKPALESKDHNSTLSGGALTAFIYPQSHNNSAVLDQKNPQDVKNGFHNKKMNRSSSNSVQFR 273

Mouse   162 ----------------------------------------------------------------- 161

  Fly   274 GWYIQPTCAITGEGLQEGLDALYDMILKRRKINKSNKR 311
             |::||||||.|:||:|||:.|:|||:||||:.:..|:
Mouse   162 -WHLQPTCAIIGDGLKEGLEKLHDMIIKRRKMLRQQKK 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl4	NP_001245408.1	P-loop_NTPase	24..311	CDD:304359	115/286 (40%)
Arl4a	NP_001034604.1	Arl4_Arl7	18..200	CDD:206719	116/289 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	197	1.000	Domainoid score	I3103
eggNOG	1	0.900	-	-		E2759_KOG0070
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4194
Inparanoid	1	1.050	247	1.000	Inparanoid score	I3251
Isobase	1	0.950	-	0	Normalized mean entropy	S772
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1457094at2759
OrthoFinder	1	1.000	-	-		FOG0002276
OrthoInspector	1	1.000	-	-		otm42926
orthoMCL	1	0.900	-	-		OOG6_106796
Panther	1	1.100	-	-	LDO	PTHR11711
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5004
SonicParanoid	1	1.000	-	-		X1505
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.810