Protein Alignment Arl4 and ARL4C

DIOPT Version :10

• Sequence 1: NP_001245408.1
• Gene: Arl4 / 43771
• FlyBaseID: FBgn0039889
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_001269360.1
• Gene: ARL4C / 10123
• HGNCID: 698
• Length: 201
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 116/299 - (38%)
• Similarity: 152/299 - (50%)
• Gaps: 109/299 - (36%)

  Fly    13 GNILDALPSQVATLHVVMLGLDSAGKTTALYRLKFDQYLNTVPTIGFNCEKVQCTLGKAKGVHFL 77
            |||...: |...:||:||||||||||||.||||||::::|||||||||.||::.:.|.|||:...
Human     2 GNISSNI-SAFQSLHIVMLGLDSAGKTTVLYRLKFNEFVNTVPTIGFNTEKIKLSNGTAKGISCH 65

  Fly    78 VWDVGGQEKLRPLWRSYTRCTDGILFVIDSVDTERMEEAKMELMRTAKCPDNQGVPVLILANKQD 142
            .|||||||||||||:||:||||||::|:||||.:|:||||.||.:..|..:|||.|:|::|||||
Human    66 FWDVGGQEKLRPLWKSYSRCTDGIIYVVDSVDVDRLEEAKTELHKVTKFAENQGTPLLVIANKQD 130

  Fly   143 LPNACGAMELEKLLGLNELYNPVPNISMPSSSDSSPTINLIGCRVSNQSITDKSLEEKKESHLHS 207
            ||.:....|:||.|.|:||        :|:::
Human   131 LPKSLPVAEIEKQLALHEL--------IPATT--------------------------------- 154

  Fly   208 SMIHIKPALESKDHNSTLSGGALTAFIYPQSHNNSAVLDQKNPQDVKNGFHNKKMNRSSSNSVQF 272
                                                                             
Human   155 ----------------------------------------------------------------- 154

  Fly   273 RGWYIQPTCAITGEGLQEGLDALYDMILKRRKINKSNKR 311
              :::||.|||.||||.||:|.||:|||||||..|..|:
Human   155 --YHVQPACAIIGEGLTEGMDKLYEMILKRRKSLKQKKK 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arl4	NP_001245408.1	P-loop containing Nucleoside Triphosphate Hydrolases	24..311	CDD:476819	111/286 (39%)
ARL4C	NP_001269360.1	Arl4_Arl7	11..192	CDD:206719	112/289 (39%)