Protein Alignment Ank and NAS6

DIOPT Version :9

• Sequence 1: NP_001162819.1
• Gene: Ank / 43770
• FlyBaseID: FBgn0011747
• Length: 1549
• Species: Drosophila melanogaster
• Sequence 2: NP_011748.3
• Gene: NAS6 / 853147
• SGDID: S000003464
• Length: 228
• Species: Saccharomyces cerevisiae
• Alignment Length: 227
• Identity: 64/227 - (28%)
• Similarity: 104/227 - (45%)
• Gaps: 16/227 - (7%)

  Fly   534 LHIAAKEGQENIVQVLLENGAENNAVTKK---GFTPLHLACKYGKQNVVQILLQNGASI---DFQ 592
            ||.|..|.:...||.||.  ::.:.:.:|   |..|||.:..:....:...||....::   |:.
Yeast     6 LHQACMENEFFKVQELLH--SKPSLLLQKDQDGRIPLHWSVSFQAHEITSFLLSKMENVNLDDYP 68

  Fly   593 GKNDVTPLHVATHYNNPSIVELLLKNGSSPNL--CARNGQCAIHIACKKNYLEIAMQLLQHGADV 655
            ..:..||.|:|....|..:|:.|......|:|  ....|...:|:|..|.:.|::..|:::||.|
Yeast    69 DDSGWTPFHIACSVGNLEVVKSLYDRPLKPDLNKITNQGVTCLHLAVGKKWFEVSQFLIENGASV 133

  Fly   656 NIISKSGFSPLHLAAQGGNVDMVQLLLEYG--VISAAAKNGLTPLHVAAQEGHVLVSQILLE-HG 717
            .|..|....|||.||..|::.:::||...|  .::...|.|.|||..|..|||...:.:|:| :|
Yeast   134 RIKDKFNQIPLHRAASVGSLKLIELLCGLGKSAVNWQDKQGWTPLFHALAEGHGDAAVLLVEKYG 198

  Fly   718 ANISERTRNGYTPLHMAAHYGHLDLVKFFIEN 749
            |........|.....:|.:.   .:.|||:.|
Yeast   199 AEYDLVDNKGAKAEDVALNE---QVKKFFLNN 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ank	NP_001162819.1	ANK	67..192	CDD:238125
		ANK repeat	72..103	CDD:293786
		Ank_2	77..167	CDD:289560
		ANK repeat	105..136	CDD:293786
		ANK repeat	138..169	CDD:293786
		ANK	204..320	CDD:238125
		ANK repeat	204..231	CDD:293786
		Ank_2	205..295	CDD:289560
		ANK repeat	233..264	CDD:293786
		ANK repeat	266..295	CDD:293786
		ANK	294..419	CDD:238125
		ANK repeat	299..330	CDD:293786
		Ank_4	300..353	CDD:290365
		ANK repeat	332..363	CDD:293786
		Ank_2	337..428	CDD:289560
		ANK	360..485	CDD:238125
		ANK repeat	365..395	CDD:293786
		ANK repeat	398..427	CDD:293786
		ANK repeat	431..462	CDD:293786
		Ank_2	436..526	CDD:289560
		ANK repeat	464..494	CDD:293786
		ANK	491..616	CDD:238125	22/87 (25%)
		ANK repeat	496..527	CDD:293786
		Ank_2	501..592	CDD:289560	16/63 (25%)
		ANK repeat	529..560	CDD:293786	8/25 (32%)
		ANK	557..682	CDD:238125	35/132 (27%)
		ANK repeat	562..590	CDD:293786	7/33 (21%)
		Ank_5	582..636	CDD:290568	14/58 (24%)
		ANK repeat	595..625	CDD:293786	9/31 (29%)
		ANK repeat	628..657	CDD:293786	9/28 (32%)
		Ank_2	633..723	CDD:289560	32/92 (35%)
		ANK repeat	661..691	CDD:293786	9/31 (29%)
		ANK	692..812	CDD:238125	19/59 (32%)
		ANK repeat	693..724	CDD:293786	12/31 (39%)
		Ank_2	698..788	CDD:289560	15/53 (28%)
		ANK repeat	726..755	CDD:293786	6/24 (25%)
		ANK repeat	759..788	CDD:293786
		ZU5	930..1034	CDD:128514
		Death_ank	1439..1521	CDD:260029
NAS6	NP_011748.3	ANKYR	1..226	CDD:223738	63/224 (28%)
		ANK repeat	1..33	CDD:293786	8/28 (29%)
		ANK repeat	35..69	CDD:293786	7/33 (21%)
		ANK repeat	71..104	CDD:293786	9/32 (28%)
		ANK repeat	107..137	CDD:293786	10/29 (34%)
		ANK repeat	139..171	CDD:293786	9/31 (29%)
		ANK repeat	173..205	CDD:293786	12/31 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100012
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810