DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and MBP1

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:NP_010227.1 Gene:MBP1 / 851503 SGDID:S000002214 Length:833 Species:Saccharomyces cerevisiae


Alignment Length:464 Identity:95/464 - (20%)
Similarity:178/464 - (38%) Gaps:118/464 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   521 AEINAQSNDKYSAL--HIAAKEGQEN--IVQVLLENGAE-----NNAVTKKGFTPLHLACKYGKQ 576
            ::||.:.|...|.|  :..:.|.:.|  :.||||.....     :..:..:..|..|.||..|..
Yeast   344 SDINDKVNKYLSKLVDYFISNEMKSNKSLPQVLLHPPPHSAPYIDAPIDPELHTAFHWACSMGNL 408

  Fly   577 NVVQILLQNGASIDFQGKNDVTPLHVATHYNN-------PSIVELLLKNGSSPNLCARNGQCAIH 634
            .:.:.|.:.|.||........|||..::.::|       |.|.:||.:.....:   ...|..||
Yeast   409 PIAEALYEAGTSIRSTNSQGQTPLMRSSLFHNSYTRRTFPRIFQLLHETVFDID---SQSQTVIH 470

  Fly   635 IACKKN--------YLEIAMQLLQHGAD-------VNIISKSGFSPLHLAAQGGNVDMVQLLLEY 684
            ...|:.        ||::.:..::..:.       :|...|:|.:.||:|::.|:|.....|::.
Yeast   471 HIVKRKSTTPSAVYYLDVVLSKIKDFSPQYRIELLLNTQDKNGDTALHIASKNGDVVFFNTLVKM 535

  Fly   685 GVISAAA-KNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIE 748
            |.::..: |.|||...:..|:    ..|:::::|.|....:.|....:|:               
Yeast   536 GALTTISNKEGLTANEIMNQQ----YEQMMIQNGTNQHVNSSNTDLNIHV--------------- 581

  Fly   749 NDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANP-NALTKDGNTALHIASNLGYVTVMESL 812
            |..:||..:::.                ::::....:| :.:|.....|.:|:.|:  ..|:.|:
Yeast   582 NTNNIETKNDVN----------------SMVIMSPVSPSDYITYPSQIATNISRNI--PNVVNSM 628

  Fly   813 KIVTSTSVIN-------SNIGAIEEKLKVMTPELMQ------ETLLSDSDDE-----SCDD---- 855
            |  ...|:.|       :.|.::::.||.::...:|      |.|...|.||     :.||    
Yeast   629 K--QMASIYNDLHEQHDNEIKSLQKTLKSISKTKIQVSLKTLEVLKESSKDENGEAQTNDDFEIL 691

  Fly   856 --LLDHNHYK-------YMATDDLKANYGQ---------DQKNFDTTNTDHDLTDVSVLNKKEIL 902
              |.:.|..|       |......|..|.|         |:....|.||..  .|.:.|.:.| |
Yeast   692 SRLQEQNTKKLRKRLIRYKRLIKQKLEYRQTVLLNKLIEDETQATTNNTVE--KDNNTLERLE-L 753

  Fly   903 PNEMSCIEL 911
            ..|::.::|
Yeast   754 AQELTMLQL 762

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125
ANK repeat 72..103 CDD:293786
Ank_2 77..167 CDD:289560
ANK repeat 105..136 CDD:293786
ANK repeat 138..169 CDD:293786
ANK 204..320 CDD:238125
ANK repeat 204..231 CDD:293786
Ank_2 205..295 CDD:289560
ANK repeat 233..264 CDD:293786
ANK repeat 266..295 CDD:293786
ANK 294..419 CDD:238125
ANK repeat 299..330 CDD:293786
Ank_4 300..353 CDD:290365
ANK repeat 332..363 CDD:293786
Ank_2 337..428 CDD:289560
ANK 360..485 CDD:238125
ANK repeat 365..395 CDD:293786
ANK repeat 398..427 CDD:293786
ANK repeat 431..462 CDD:293786
Ank_2 436..526 CDD:289560 2/4 (50%)
ANK repeat 464..494 CDD:293786
ANK 491..616 CDD:238125 27/110 (25%)
ANK repeat 496..527 CDD:293786 2/5 (40%)
Ank_2 501..592 CDD:289560 20/79 (25%)
ANK repeat 529..560 CDD:293786 8/39 (21%)
ANK 557..682 CDD:238125 31/146 (21%)
ANK repeat 562..590 CDD:293786 8/27 (30%)
Ank_5 582..636 CDD:290568 15/60 (25%)
ANK repeat 595..625 CDD:293786 8/36 (22%)
ANK repeat 628..657 CDD:293786 6/43 (14%)
Ank_2 633..723 CDD:289560 23/105 (22%)
ANK repeat 661..691 CDD:293786 8/29 (28%)
ANK 692..812 CDD:238125 19/120 (16%)
ANK repeat 693..724 CDD:293786 7/30 (23%)
Ank_2 698..788 CDD:289560 10/90 (11%)
ANK repeat 726..755 CDD:293786 4/28 (14%)
ANK repeat 759..788 CDD:293786 1/29 (3%)
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
MBP1NP_010227.1 KilA-N 22..93 CDD:367917
ANKYR 363..544 CDD:223738 39/183 (21%)
ANK repeat 396..425 CDD:293786 9/28 (32%)
ANK repeat 427..510 CDD:293786 15/85 (18%)
ANK repeat 512..543 CDD:293786 8/30 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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