DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank and ANK1

DIOPT Version :9

Sequence 1:	NP_001162819.1	Gene:	Ank / 43770	FlyBaseID:	FBgn0011747	Length:	1549	Species:	Drosophila melanogaster
Sequence 2:	NP_001331981.1	Gene:	ANK1 / 831855	AraportID:	AT5G02620	Length:	547	Species:	Arabidopsis thaliana

Alignment Length:	402	Identity:	101/402 - (25%)
Similarity:	169/402 - (42%)	Gaps:	122/402 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 TPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHD--KIVAVLLENDVRGKVRLP 203
            |||:.|.:|                      |.|.|.:.|...||  ::..:|.|.:..|:.
plant    19 TPLHTAVRE----------------------GKTDLLLEMIGEHDGVELKELLAEQNQSGET--- 58

  Fly   204 ALHIAAKKNDVNAAKLLLQHDPN--ADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYV-AK 265
            ||::||:....:..|:|::|..:  |...:|:||...||||..||:.:..:|:....::::. ..
plant    59 ALYVAAEYGYTDMVKILMKHSDSVLAGTKAKNGFDAFHIAAKNGNLQVLDVLIEANPELSFTFDS 123

  Fly   266 HNITPLHVACKWGKLSLCTLLLCRGAKIDAATR-DGLTPLHCASRSGHVEVIKHLLQQNAPILTK 329
            ...|.||.|...|...:...||.:|..:.|..| :|.|.||.|:|:||..::|.|:::.|.::|:
plant   124 SKTTALHTAASQGHGEIVCFLLDKGVDLAAIARSNGKTALHSAARNGHTVIVKKLIEKKAGMVTR 188

  Fly   330 T-KNGLSALHMAAQGEHDEAAHLLLD------NKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLD 387
            . |.|.:|||||.:|::.|...:|::      |.|                             |
plant   189 VDKKGQTALHMAVKGQNTEIVDVLMEADGSLINSA-----------------------------D 224

  Fly   388 YKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLL 452
            .|.|         ||||||.:|||   .|:::..                  ||.      ::||
plant   225 NKGN---------TPLHIAVRKNR---AEVIVDQ------------------SFK------LFLL 253

  Fly   453 QHEASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAIA--REGQTPLHVASRLGNINIIML 515
            |                .|.:......|::.:|:..:|..:|  :.|:|.|.:|.:.|...|:.|
plant   254 Q----------------KLESFLYSLQIVQTVLKYCEVSRVAVNKSGETALDIAEKTGLHEIVPL 302

  Fly   516 LLQHGAEINAQS 527
            |.:.|.: ||:|
plant   303 LQKIGMQ-NARS 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank	NP_001162819.1	ANK	67..192	CDD:238125	11/52 (21%)
		ANK repeat	72..103	CDD:293786
		Ank_2	77..167	CDD:289560	5/25 (20%)
		ANK repeat	105..136	CDD:293786
		ANK repeat	138..169	CDD:293786	5/27 (19%)
		ANK	204..320	CDD:238125	37/119 (31%)
		ANK repeat	204..231	CDD:293786	8/28 (29%)
		Ank_2	205..295	CDD:289560	25/92 (27%)
		ANK repeat	233..264	CDD:293786	9/31 (29%)
		ANK repeat	266..295	CDD:293786	8/28 (29%)
		ANK	294..419	CDD:238125	39/132 (30%)
		ANK repeat	299..330	CDD:293786	12/30 (40%)
		Ank_4	300..353	CDD:290365	21/53 (40%)
		ANK repeat	332..363	CDD:293786	11/36 (31%)
		Ank_2	337..428	CDD:289560	22/96 (23%)
		ANK	360..485	CDD:238125	20/124 (16%)
		ANK repeat	365..395	CDD:293786	3/29 (10%)
		ANK repeat	398..427	CDD:293786	10/28 (36%)
		ANK repeat	431..462	CDD:293786	5/30 (17%)
		Ank_2	436..526	CDD:289560	20/91 (22%)
		ANK repeat	464..494	CDD:293786	4/29 (14%)
		ANK	491..616	CDD:238125	13/39 (33%)
		ANK repeat	496..527	CDD:293786	11/30 (37%)
		Ank_2	501..592	CDD:289560	10/27 (37%)
		ANK repeat	529..560	CDD:293786
		ANK	557..682	CDD:238125
		ANK repeat	562..590	CDD:293786
		Ank_5	582..636	CDD:290568
		ANK repeat	595..625	CDD:293786
		ANK repeat	628..657	CDD:293786
		Ank_2	633..723	CDD:289560
		ANK repeat	661..691	CDD:293786
		ANK	692..812	CDD:238125
		ANK repeat	693..724	CDD:293786
		Ank_2	698..788	CDD:289560
		ANK repeat	726..755	CDD:293786
		ANK repeat	759..788	CDD:293786
		ZU5	930..1034	CDD:128514
		Death_ank	1439..1521	CDD:260029
ANK1	NP_001331981.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8400
orthoMCL	1	0.900	-	-		OOG6_100012
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810