DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank and AT5G14230

DIOPT Version :9

Sequence 1:	NP_001162819.1	Gene:	Ank / 43770	FlyBaseID:	FBgn0011747	Length:	1549	Species:	Drosophila melanogaster
Sequence 2:	NP_196927.4	Gene:	AT5G14230 / 831273	AraportID:	AT5G14230	Length:	751	Species:	Arabidopsis thaliana

Alignment Length:	618	Identity:	149/618 - (24%)
Similarity:	244/618 - (39%)	Gaps:	157/618 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   349 AHLLLDNKAPVDEVTVDY------LTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIAC 407
            :.::|.:::| .||.|:|      :|||.:|.:.|:..:.|.||:..|:.|.:...||... :|.
plant    58 SEVVLRDESP-SEVRVEYEEFKTDVTALFLAVNFGNAALVKELLNIGADVNQKLFRGFATT-VAV 120

  Fly   408 KKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLA 472
            ::....:.|:|:|.||:..|..|:    |..||..|....|..|:    ..||  ||.:..:|..
plant   121 REGHFDVFEILLKAGASQPACEEA----LVGASCHGRSRFVELLM----GTDL--IRPQVAVHAL 175

  Fly   473 AR-------------------ANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQ 518
            |.                   ||..|  |:||:|:|.........|.|..|.....::.:.:|||
plant   176 ATACCRGFVDVVGTLLKCGVDANSTD--RLLLQSSKPSLYTNVDCTALVAAIVNRQVSAVRVLLQ 238

  Fly   519 HGAEI-------------------------------------------------------NAQSN 528
            .|.:.                                                       ||..|
plant   239 AGVKTDIMVRLGAWSWDTNTGEEFRVGAGVAEPYPLTWCAVEYFETSGDILRLLLKLQSPNALHN 303

  Fly   529 DKYSALHIAAKEGQENIVQVLLENGAENNA--VTKKG--FTPLHLACKYGKQNVVQILLQNGASI 589
            .: :.||.|...|.:..|.|||:.||:..|  .|.:|  ..|:|:|.:.|...::|.|:  |...
plant   304 GR-TLLHHAVLCGNKAAVSVLLDCGADPEAPIKTSRGIELRPIHIAARDGSVEIIQQLV--GFGC 365

  Fly   590 DFQGKNDV--TPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNY---LE-IAMQL 648
            |...||||  |.|.::..:.:|..|::|..:|:...|..:.|..|:.||....:   || :.::|
plant   366 DINSKNDVGNTALLISIKHKHPECVKVLALDGADFGLVNKFGHSAVSIAESNKWSLGLERVILEL 430

  Fly   649 LQHGADVNIISKSGFSPLHLAAQGGNVDMVQLL-------LEYGVISAAAKNGLTPLHVAAQEGH 706
            ::.|...:..:.|.||||...||.|:.:.::.|       |:|     ..:.|.:...:||..||
plant   431 IRFGVVPHSSNASVFSPLLYGAQAGDAEALKALVKAQDIYLDY-----QDEEGFSAAMLAAMNGH 490

  Fly   707 VLVSQILLEHGANI-------------SERTRN----------------------GYTPLHMAAH 736
            |...::|:..||::             ||:..|                      |:..||.||.
plant   491 VEAFRVLVYAGADVKLYNNSGDTVVSLSEQNGNRDVIEKVMLEFALEKDSRNMAGGFYALHCAAR 555

  Fly   737 YGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIAS 801
            .|.:..||........:::....|||||..||::||..:...|:...||.||....|...|.:|:
plant   556 RGDVKAVKLLSGKGYSLDIPDGDGYTPLMLAAREGHGHMCEYLISCGANCNAKNGRGEKLLDLAT 620

  Fly   802 NLGYVTVMESLK---IVTSTSVINSNIGAIEEK 831
            ......:...|.   ::..:||:....|...:|
plant   621 GDAEKVIRNELSRRFVIEGSSVMKHTKGGKGKK 653

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank	NP_001162819.1	ANK	67..192	CDD:238125
		ANK repeat	72..103	CDD:293786
		Ank_2	77..167	CDD:289560
		ANK repeat	105..136	CDD:293786
		ANK repeat	138..169	CDD:293786
		ANK	204..320	CDD:238125
		ANK repeat	204..231	CDD:293786
		Ank_2	205..295	CDD:289560
		ANK repeat	233..264	CDD:293786
		ANK repeat	266..295	CDD:293786
		ANK	294..419	CDD:238125	20/75 (27%)
		ANK repeat	299..330	CDD:293786
		Ank_4	300..353	CDD:290365	0/3 (0%)
		ANK repeat	332..363	CDD:293786	3/13 (23%)
		Ank_2	337..428	CDD:289560	24/84 (29%)
		ANK	360..485	CDD:238125	40/149 (27%)
		ANK repeat	365..395	CDD:293786	11/35 (31%)
		ANK repeat	398..427	CDD:293786	8/28 (29%)
		ANK repeat	431..462	CDD:293786	8/30 (27%)
		Ank_2	436..526	CDD:289560	28/163 (17%)
		ANK repeat	464..494	CDD:293786	11/48 (23%)
		ANK	491..616	CDD:238125	39/185 (21%)
		ANK repeat	496..527	CDD:293786	9/85 (11%)
		Ank_2	501..592	CDD:289560	30/149 (20%)
		ANK repeat	529..560	CDD:293786	11/32 (34%)
		ANK	557..682	CDD:238125	39/141 (28%)
		ANK repeat	562..590	CDD:293786	8/29 (28%)
		Ank_5	582..636	CDD:290568	16/55 (29%)
		ANK repeat	595..625	CDD:293786	9/31 (29%)
		ANK repeat	628..657	CDD:293786	8/32 (25%)
		Ank_2	633..723	CDD:289560	27/113 (24%)
		ANK repeat	661..691	CDD:293786	11/36 (31%)
		ANK	692..812	CDD:238125	37/154 (24%)
		ANK repeat	693..724	CDD:293786	11/43 (26%)
		Ank_2	698..788	CDD:289560	31/124 (25%)
		ANK repeat	726..755	CDD:293786	9/50 (18%)
		ANK repeat	759..788	CDD:293786	12/28 (43%)
		ZU5	930..1034	CDD:128514
		Death_ank	1439..1521	CDD:260029
AT5G14230	NP_196927.4	ANK repeat	82..110	CDD:293786	10/27 (37%)
		Ank_2	84..201	CDD:403870	32/127 (25%)
		ANK repeat	112..142	CDD:293786	9/30 (30%)
		ANK repeat	151..201	CDD:293786	11/55 (20%)
		ANK repeat	218..247	CDD:293786	7/28 (25%)
		Ank_2	221..332	CDD:403870	19/111 (17%)
		ANK repeat	303..334	CDD:293786	12/31 (39%)
		Ank_2	308..404	CDD:403870	32/97 (33%)
		ANK repeat	336..371	CDD:293786	10/36 (28%)
		ANK repeat	373..404	CDD:293786	8/30 (27%)
		ANKYR	421..634	CDD:223738	53/217 (24%)
		ANK repeat	477..508	CDD:293786	9/30 (30%)
		ANK repeat	510..576	CDD:293786	11/65 (17%)
		ANK repeat	578..609	CDD:293786	14/30 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3248
orthoMCL	1	0.900	-	-		OOG6_100012
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910