DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank and XBAT33

DIOPT Version :9

Sequence 1:	NP_001162819.1	Gene:	Ank / 43770	FlyBaseID:	FBgn0011747	Length:	1549	Species:	Drosophila melanogaster
Sequence 2:	NP_196344.2	Gene:	XBAT33 / 830618	AraportID:	AT5G07270	Length:	513	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	140/577 - (24%)
Similarity:	210/577 - (36%)	Gaps:	144/577 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LDNKNGIIKQNDATISFLRAARSGDIKKVMDFLDCGEISDINSCNA-----NGLNA-LHLAAKDG 84
            :.|..|.....:..:|   |||.||..:....|||      |.|.|     .|||: ||.||..|
plant     1 MGNSFGCSASGERLVS---AARDGDFVEAKMLLDC------NPCLAKYSTFGGLNSPLHFAAAKG 56

  Fly    85 YVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANV-NVQSLNGFTPLYMAAQ 148
            :.:|...||..|..:::....|.|||..|...|..:|:..|:|:..|| ....|.|.|.|:.||.
plant    57 HNEIVGLLLENGADVNSRNYCGQTALMQACRYGHWEVVQTLLLFRCNVTRADYLAGRTALHFAAV 121

  Fly   149 ENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKND 213
            ..|..|.|.:||:           |.|        .||:.:            ||...:...||.
plant   122 NGHARCIRLVLAD-----------FLP--------SDKLNS------------LPETGVVTAKNK 155

  Fly   214 VNAAKLLLQHDPNADIVSKS---GFTPLHIAAHYGNVDIATLLLNNKADVNYVAKH--------- 266
            ...:.|       :..|:|:   |.|.||:||..|..|...|||:.:|:|:.|..|
plant   156 SEQSAL-------SKFVNKAADGGITALHMAALNGLFDCVQLLLDLEANVSAVTFHYGTSMDMIG 213

  Fly   267 -NITPLHVACKWGKLSLCTLLLCRGAK-----------IDAA---TRDGLTPLHCASRSGHVEVI 316
             ..||||.|...|.|..|.:||.|||:           ||.|   :|..|.||...:....:...
plant   214 AGSTPLHYAACGGNLKCCQILLARGARKMTLNCNGWLPIDIARMWSRHWLEPLLSPNSDVVIPAF 278

  Fly   317 KHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYL----TALHVAAHCG 377
            .|....:.|:       ||.|::|.:        ..|.:....|||.:..:    |....|..|.
plant   279 PHSNYLSLPL-------LSILNIARE--------FGLQSATIGDEVDICAVCLERTCTVAAEGCE 328

  Fly   378 HVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLT-----PLH 437
            |....:..|...::.|..::....|..|.|.         |.:||........|.||     |:.
plant   329 HQLCVRCALYLCSSSNVPSVTVGPPGSIPCP---------LCRHGITAFKRLPSSLTREMKLPMS 384

  Fly   438 VASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQAD--IIRILLRSAKVDA--IAREGQ 498
            :.....|:                       ||.....:|:.  ......||:|..|  ::.:..
plant   385 LGFCAPCM-----------------------LHTGDTTDQSSPTCPPTEQRSSKTRAASVSSDIF 426

  Fly   499 TPLHVASRLGNINIIMLLLQHGAEINAQSN--DKYSALHIAAKEGQENIVQVLLENG 553
            .|: ..|...::||.|.....|...|.:::  :::|..|:.:...:....|..:|.|
plant   427 CPV-TCSPFPSVNIPMCTCNEGTCPNFETHGTERHSEEHVESSPSRTTTEQEKIEEG 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank	NP_001162819.1	ANK	67..192	CDD:238125	41/131 (31%)
		ANK repeat	72..103	CDD:293786	12/31 (39%)
		Ank_2	77..167	CDD:289560	31/90 (34%)
		ANK repeat	105..136	CDD:293786	11/31 (35%)
		ANK repeat	138..169	CDD:293786	10/30 (33%)
		ANK	204..320	CDD:238125	41/142 (29%)
		ANK repeat	204..231	CDD:293786	3/26 (12%)
		Ank_2	205..295	CDD:289560	34/113 (30%)
		ANK repeat	233..264	CDD:293786	13/33 (39%)
		ANK repeat	266..295	CDD:293786	15/49 (31%)
		ANK	294..419	CDD:238125	25/131 (19%)
		ANK repeat	299..330	CDD:293786	5/30 (17%)
		Ank_4	300..353	CDD:290365	9/52 (17%)
		ANK repeat	332..363	CDD:293786	7/30 (23%)
		Ank_2	337..428	CDD:289560	18/94 (19%)
		ANK	360..485	CDD:238125	23/135 (17%)
		ANK repeat	365..395	CDD:293786	6/33 (18%)
		ANK repeat	398..427	CDD:293786	6/28 (21%)
		ANK repeat	431..462	CDD:293786	5/35 (14%)
		Ank_2	436..526	CDD:289560	15/93 (16%)
		ANK repeat	464..494	CDD:293786	7/33 (21%)
		ANK	491..616	CDD:238125	13/67 (19%)
		ANK repeat	496..527	CDD:293786	7/30 (23%)
		Ank_2	501..592	CDD:289560	11/55 (20%)
		ANK repeat	529..560	CDD:293786	5/25 (20%)
		ANK	557..682	CDD:238125
		ANK repeat	562..590	CDD:293786
		Ank_5	582..636	CDD:290568
		ANK repeat	595..625	CDD:293786
		ANK repeat	628..657	CDD:293786
		Ank_2	633..723	CDD:289560
		ANK repeat	661..691	CDD:293786
		ANK	692..812	CDD:238125
		ANK repeat	693..724	CDD:293786
		Ank_2	698..788	CDD:289560
		ANK repeat	726..755	CDD:293786
		ANK repeat	759..788	CDD:293786
		ZU5	930..1034	CDD:128514
		Death_ank	1439..1521	CDD:260029
XBAT33	NP_196344.2	Ank_2	<3..75	CDD:403870	26/80 (33%)
		ANK repeat	46..75	CDD:293786	10/28 (36%)
		Ank_2	49..132	CDD:403870	29/82 (35%)
		ANK repeat	77..108	CDD:293786	11/30 (37%)
		Ank_2	116..245	CDD:403870	47/166 (28%)
		ANK repeat	156..202	CDD:293786	16/52 (31%)
		ANK repeat	204..239	CDD:293786	12/34 (35%)
		RING_Ubox	311..363	CDD:418438	10/60 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3248
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910