DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ank and AT4G03480

DIOPT Version :9

Sequence 1:	NP_001162819.1	Gene:	Ank / 43770	FlyBaseID:	FBgn0011747	Length:	1549	Species:	Drosophila melanogaster
Sequence 2:	NP_192257.5	Gene:	AT4G03480 / 827906	AraportID:	AT4G03480	Length:	659	Species:	Arabidopsis thaliana

Alignment Length:	584	Identity:	130/584 - (22%)
Similarity:	231/584 - (39%)	Gaps:	120/584 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   307 ASRSGHVEVIKHLLQQNAPI-LTKTKNGLSALHMAAQGEHDE-AAHLLLDNKAPVDEVTVDYLTA 369
            |.|:|::|:::.|.....|: ..|:..|.|.||:||...|.| ..:::.:....:.|....|...
plant   130 AMRAGNIELLEKLKSYETPMACLKSDGGDSVLHLAAASGHLELVKNIITECPCLLLEPNSKYQIP 194

  Fly   370 LHVAAHCGHVKVAKLLLDYKANPNARA---------------LNGFTPLHIACKKNRIKM-VELL 418
            |||||..|...|.|.|:......:.|.               ::|.||||.|.|....|. |..|
plant   195 LHVAARAGRSAVVKALVASVLYFSPRVPEEDRDRLNIYVLKDIDGDTPLHAALKDLHEKAEVSHL 259

  Fly   419 IKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRI 483
            :::...|...:.|.|. :|... ..||:.          :|..|.:.||...|......|..:
plant   260 LRYQERIRKLSLSHLI-MHWRR-SRCISF----------SDASTRQMETAACLVNADQHASFL-- 310

  Fly   484 LLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQH-GAEINAQSNDKYSALHIAAKEGQENIVQ 547
                     ..::|.:||::|...||::::..:|.. |.:|..:::...|.|     ||::::
plant   311 ---------ANKDGTSPLYLAVEAGNVSLVRAMLNRPGNKIQGKTSTLASQL-----EGRKSL-- 359

  Fly   548 VLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASI----DFQGKNDVTPLHVAT---H 605
                               ||.|.|....:|:.::|.:..|:    |.:|:   |.|.|..   :
plant   360 -------------------LHAALKAKNTDVLNVILNDDPSLVNERDEEGR---TCLSVGASMGY 402

  Fly   606 YNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGAD-VNIISKSGFSPLHLA 669
            |.  .|.:||.::..|...|.::|...||:|.:|.:|::..::|:...| ..:::|.|.:.||:|
plant   403 YK--GICKLLDRSTKSVYECDKDGSFPIHMAVEKGHLKVVKEILKRCPDSKELVNKQGQNMLHIA 465

  Fly   670 AQGGNVDMVQLLLEY--------GVISAAAKNGLTPLHVAAQEGHVLVSQILLEHGAN----ISE 722
            |:...|.  ..||.|        .:|.....:|..|||:|...........|....:.    ::.
plant   466 AKSAKVG--SFLLGYIRRLDTENHLIEEQDVDGNAPLHLATINWRCRTVDKLAAFASTETKILNI 528

  Fly   723 RTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPN 787
            :.::|..||.:|    .|:|...::..:....|.....|.|    ...|.:....:.||.::.|.
plant   529 QNKDGLRPLDIA----ELNLQPDYVLRERLTLMVLLCVYAP----KSVGWLPTSGMTLRSRSEPL 585

  Fly   788 ALTKDGNTALHIASNLGYVTVMESLKIVTSTSV---INSNIGAIEEKLKVMTPELMQETLLSDS 848
            ...|..:   ||.:.|...|::.::......::   .||:           .|.:...||..||
plant   586 DAKKYKD---HINALLLVATLVATVTFAAGFTIPGGFNSS-----------APNMGMATLADDS 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank	NP_001162819.1	ANK	67..192	CDD:238125
		ANK repeat	72..103	CDD:293786
		Ank_2	77..167	CDD:289560
		ANK repeat	105..136	CDD:293786
		ANK repeat	138..169	CDD:293786
		ANK	204..320	CDD:238125	4/12 (33%)
		ANK repeat	204..231	CDD:293786
		Ank_2	205..295	CDD:289560
		ANK repeat	233..264	CDD:293786
		ANK repeat	266..295	CDD:293786
		ANK	294..419	CDD:238125	36/129 (28%)
		ANK repeat	299..330	CDD:293786	6/23 (26%)
		Ank_4	300..353	CDD:290365	15/47 (32%)
		ANK repeat	332..363	CDD:293786	9/31 (29%)
		Ank_2	337..428	CDD:289560	29/107 (27%)
		ANK	360..485	CDD:238125	34/140 (24%)
		ANK repeat	365..395	CDD:293786	10/29 (34%)
		ANK repeat	398..427	CDD:293786	11/29 (38%)
		ANK repeat	431..462	CDD:293786	6/30 (20%)
		Ank_2	436..526	CDD:289560	18/90 (20%)
		ANK repeat	464..494	CDD:293786	4/29 (14%)
		ANK	491..616	CDD:238125	28/132 (21%)
		ANK repeat	496..527	CDD:293786	9/31 (29%)
		Ank_2	501..592	CDD:289560	19/95 (20%)
		ANK repeat	529..560	CDD:293786	4/30 (13%)
		ANK	557..682	CDD:238125	33/132 (25%)
		ANK repeat	562..590	CDD:293786	7/31 (23%)
		Ank_5	582..636	CDD:290568	16/60 (27%)
		ANK repeat	595..625	CDD:293786	8/32 (25%)
		ANK repeat	628..657	CDD:293786	8/29 (28%)
		Ank_2	633..723	CDD:289560	24/102 (24%)
		ANK repeat	661..691	CDD:293786	10/37 (27%)
		ANK	692..812	CDD:238125	24/123 (20%)
		ANK repeat	693..724	CDD:293786	6/34 (18%)
		Ank_2	698..788	CDD:289560	17/93 (18%)
		ANK repeat	726..755	CDD:293786	6/28 (21%)
		ANK repeat	759..788	CDD:293786	6/28 (21%)
		ZU5	930..1034	CDD:128514
		Death_ank	1439..1521	CDD:260029
AT4G03480	NP_192257.5	ANK	157..335	CDD:238125	48/200 (24%)
		Ank_4	157..211	CDD:290365	18/53 (34%)
		ANK repeat	190..236	CDD:293786	11/45 (24%)
		Ank_2	<310..387	CDD:289560	20/113 (18%)
		ANK	312..444	CDD:238125	37/162 (23%)
		ANK repeat	314..344	CDD:293786	9/29 (31%)
		ANK repeat	358..387	CDD:293786	7/49 (14%)
		Ank_2	360..449	CDD:289560	25/93 (27%)
		ANK	384..515	CDD:238125	35/137 (26%)
		ANK repeat	389..421	CDD:293786	9/36 (25%)
		ANK repeat	423..448	CDD:293786	7/24 (29%)
		Ank_2	428..515	CDD:289560	23/88 (26%)
		PGG	588..>659	CDD:290670	12/62 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920