DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ank and AT4G14390

DIOPT Version :9

Sequence 1:	NP_001162819.1	Gene:	Ank / 43770	FlyBaseID:	FBgn0011747	Length:	1549	Species:	Drosophila melanogaster
Sequence 2:	NP_193175.2	Gene:	AT4G14390 / 827084	AraportID:	AT4G14390	Length:	694	Species:	Arabidopsis thaliana

Alignment Length:	732	Identity:	171/732 - (23%)
Similarity:	272/732 - (37%)	Gaps:	190/732 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 NHDNCCRTLL---ANGANP-SLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAK 210
            :||...||.|   .:|:.. |.|..||.|||.     |..:.|...|.|     :||..|: |.:
plant    39 SHDQQNRTYLPMNIHGSQDFSQSGGDGVTPLT-----GDTESVPEFLTN-----LRLSDLY-AIR 92

  Fly   211 KNDVNAAKLLLQ--HDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHV 273
            ..||.....:..  .|.|.:.:.|.....:.:|.          :.:|..|         :.||:
plant    93 GEDVRMIPEVFSKISDGNKECLEKLRSRGISVAR----------IKSNTGD---------SILHL 138

  Fly   274 ACKWGKLSLCTLLLCRGAK-IDAATRDGLTPLHCASRSGHVEVIKHLL---------------QQ 322
            |..||.|.|...::|...: :......|.||||.|:.|||..:::..:               ::
plant   139 AVTWGHLELVKEIVCECPRLLLEQNSSGQTPLHVAAHSGHTTIVEAFVALVTFSSARLCNEESER 203

  Fly   323 NAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDY-LTALHVAAHCGHVKVAKLLL 386
            ..|.:.|.|:|.:||:.|.:|.:.|.|..|::.......:...| :::|.||.:.|.|.:.|.:|
plant   204 MNPYVLKDKDGNTALYYAIEGRYFEMAVCLVNANQDAPFLGNKYGVSSLFVAINTGDVSLVKAIL 268

  Fly   387 DYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVA----SFMGCINI 447
            ....|.:.:.           ||             :|:.:..:...:..|||    |..|.:::
plant   269 KIIGNKDLKG-----------KK-------------SNLESKLQGQKSLAHVALVTQSIAGVLDV 309

  Fly   448 VIYLLQHEASADLPTIRGETPLHLAARANQAD-IIRILLRSAK-VDAIAREGQTPLHVASRLGNI 510
            :  |.::.:..|...|.|.|.|.|||.....: :..:|.||.| |....::|..|:|.
plant   310 I--LDEYPSLMDERDINGWTCLSLAAHIGYYEGVCNLLERSTKGVYVCDQDGSFPIHT------- 365

  Fly   511 NIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLEN-GAENNAVTKKGFTPLHLACKYG 574
                                      ||::|.||||:..::. ....:.:.|.|...||:|.|.|
plant   366 --------------------------AAEKGHENIVEEFIKRCPGSKHLLNKLGQNVLHIAAKNG 404

  Fly   575 KQNVVQILLQN------GASIDFQGKNDVTPLHVAT---HYNNPSIVELLLKNGSSPNLCARNGQ 630
            |..:..:|:.|      |...|..|.   ||||:|.   |:.:   :..|.::.....:..:||.
plant   405 KFWISNMLIINKDTEHLGVGQDVDGN---TPLHLAVMNWHFKS---ITWLARSSKILKVRNKNGL 463

  Fly   631 CAIHIA---CKKNYL---EIAMQLLQHGADVNIISKSGFSPLHLAAQ-------GGNVDMVQLLL 682
            .|..||   .|.:|:   ...:.||.:.     |...||..:|...:       ..|.|.|..|
plant   464 RARDIAEREVKPHYIFQERWTLALLLYA-----IHSRGFESVHSLTKPSVPLDPKNNRDYVNTL- 522

  Fly   683 EYGVISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLV---K 744
                           |.|||     ||:.:....|..|.    .|:.  ..|.|.|...|.   .
plant   523 ---------------LLVAA-----LVATMTFAAGFTIP----GGFN--SSAPHLGRATLATNPT 561

  Fly   745 FFIENDADI-EMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTV 808
            .||....|| .|.|::....:...||.|..::|...| |.|.|  |.......:.:|...|.||.
plant   562 LFIFLVLDILAMQSSVATIGILIWAQLGDPVLIRSSL-HVALP--LLLFALLCMPLAFLFGVVTA 623

  Fly   809 MESLK----IVTSTSVI 821
            :..:|    |:...||:
plant   624 VGHVKWLVVIICIISVL 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ank	NP_001162819.1	ANK	67..192	CDD:238125	15/45 (33%)
		ANK repeat	72..103	CDD:293786
		Ank_2	77..167	CDD:289560	6/20 (30%)
		ANK repeat	105..136	CDD:293786
		ANK repeat	138..169	CDD:293786	7/22 (32%)
		ANK	204..320	CDD:238125	27/118 (23%)
		ANK repeat	204..231	CDD:293786	6/28 (21%)
		Ank_2	205..295	CDD:289560	18/92 (20%)
		ANK repeat	233..264	CDD:293786	3/30 (10%)
		ANK repeat	266..295	CDD:293786	8/29 (28%)
		ANK	294..419	CDD:238125	31/140 (22%)
		ANK repeat	299..330	CDD:293786	10/45 (22%)
		Ank_4	300..353	CDD:290365	19/67 (28%)
		ANK repeat	332..363	CDD:293786	8/30 (27%)
		Ank_2	337..428	CDD:289560	18/91 (20%)
		ANK	360..485	CDD:238125	26/130 (20%)
		ANK repeat	365..395	CDD:293786	9/30 (30%)
		ANK repeat	398..427	CDD:293786	3/28 (11%)
		ANK repeat	431..462	CDD:293786	7/34 (21%)
		Ank_2	436..526	CDD:289560	22/95 (23%)
		ANK repeat	464..494	CDD:293786	11/31 (35%)
		ANK	491..616	CDD:238125	29/134 (22%)
		ANK repeat	496..527	CDD:293786	3/30 (10%)
		Ank_2	501..592	CDD:289560	20/97 (21%)
		ANK repeat	529..560	CDD:293786	7/31 (23%)
		ANK	557..682	CDD:238125	36/146 (25%)
		ANK repeat	562..590	CDD:293786	10/33 (30%)
		Ank_5	582..636	CDD:290568	15/62 (24%)
		ANK repeat	595..625	CDD:293786	7/32 (22%)
		ANK repeat	628..657	CDD:293786	9/34 (26%)
		Ank_2	633..723	CDD:289560	22/102 (22%)
		ANK repeat	661..691	CDD:293786	7/36 (19%)
		ANK	692..812	CDD:238125	32/123 (26%)
		ANK repeat	693..724	CDD:293786	8/30 (27%)
		Ank_2	698..788	CDD:289560	27/93 (29%)
		ANK repeat	726..755	CDD:293786	9/32 (28%)
		ANK repeat	759..788	CDD:293786	8/28 (29%)
		ZU5	930..1034	CDD:128514
		Death_ank	1439..1521	CDD:260029
AT4G14390	NP_193175.2	ANK	127..268	CDD:238125	37/149 (25%)
		Ank_2	136..239	CDD:289560	28/102 (27%)
		ANK repeat	165..211	CDD:293786	10/45 (22%)
		ANK repeat	213..238	CDD:293786	8/24 (33%)
		ANKYR	291..505	CDD:223738	62/259 (24%)
		ANK	319..448	CDD:238125	42/167 (25%)
		ANK repeat	324..356	CDD:293786	11/31 (35%)
		ANK repeat	358..390	CDD:293786	10/64 (16%)
		ANK repeat	392..426	CDD:293786	10/33 (30%)
		PGG	513..620	CDD:290670	33/136 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1011028at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920