DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ank and ankrd34ba

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:XP_689430.3 Gene:ankrd34ba / 560938 ZFINID:ZDB-GENE-091118-17 Length:544 Species:Danio rerio


Alignment Length:588 Identity:116/588 - (19%)
Similarity:196/588 - (33%) Gaps:186/588 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   523 INAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACK--------YGKQNVV 579
            ||...|....|::::    :..:.::|||.||..|...:.|.|||.:||:        ..|..:|
Zfish     7 INVDGNSLLKAVYLS----RLRLTRLLLEGGAYINESNECGETPLMVACRSRHTDHQSVPKVKMV 67

  Fly   580 QILLQNGASIDFQGKNDVTPL-HVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLE 643
            ..||::||..:.|.|:..|.| |.......|.:|||||.||:.|              |.:::  
Zfish    68 GYLLESGADPNIQDKSGRTALMHACLEQAGPEVVELLLSNGADP--------------CLEDH-- 116

  Fly   644 IAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGVISAAAKNG-----LTPLHVAAQ 703
                             :|.|.|..|..|...:.::||     |.|....|     :||..:|. 
Zfish   117 -----------------TGSSALIYAINGSGEETLKLL-----IDACKARGKEVIIITPDKLAC- 158

  Fly   704 EGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAA 768
             |..:..|.|             ...||.|...:.:.........:.:||.:|::...|.....|
Zfish   159 -GKQMAKQYL-------------SIPPLAMVEQWDNPSSSAVPCASPSDILLSTSPQGTLSSSPA 209

  Fly   769 QQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLKIVTSTSVINSNIGAI----- 828
            :  ||....       :|.::|....|:....|.|                 :||.:..:     
Zfish   210 E--HIFYFQ-------DPQSMTNSQPTSPSHQSPL-----------------VNSRVSKLHNLQR 248

  Fly   829 ---EEKLKVMTPELMQETLLSDSDDESCDDLLDHNHYKYM--------------ATDDLK----- 871
               |..||:....|.|:...|.:..|...|:.......:.              .:.:||     
Zfish   249 LHSEPWLKIPHAFLAQQHAKSITATEELPDITPEEEMSFRMNRLTFGNMPLSRHCSVELKEAGCL 313

  Fly   872 ----ANYGQDQK---------NFDTTNTDHDLTDVSVLNKKEI------------LPN-EMSCIE 910
                .|.|:..:         :||:.::.|.|:..::.:|..:            ||| .:|.:.
Zfish   314 SQRQGNNGERLRPEGALCRNMSFDSLSSLHSLSHPNLHSKSSMDAFPAEKDPDKSLPNLAVSSLR 378

  Fly   911 LTEIGHKPDNVVIAR--------SQVHLGFLVSFLVDARGGSMRGYRHNGVR--IIVPPKACAEP 965
                     |::..|        |...|...::...:.|.|.....||...|  .:|..:...|.
Zfish   379 ---------NIIQRRKLGMDHYSSDSQLSVSLANSPEDRKGQQERKRHANTRSPTLVGSRESLES 434

  Fly   966 TRITCRYVKPQRVVNPPPLMEGEALVSRILEMSPVD---GMFLSPITLEVP-----HYGTLRKNE 1022
            ..:|..:.:     ||   :..|...|.:| :.|:.   ..||.|:....|     ..|.|..|.
Zfish   435 ASLTHLHRR-----NP---ISYERRGSGVL-LDPISHPRAGFLPPLNQHAPIPNITPSGNLSANN 490

  Fly  1023 REI 1025
            :.:
Zfish   491 KSV 493

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125
ANK repeat 72..103 CDD:293786
Ank_2 77..167 CDD:289560
ANK repeat 105..136 CDD:293786
ANK repeat 138..169 CDD:293786
ANK 204..320 CDD:238125
ANK repeat 204..231 CDD:293786
Ank_2 205..295 CDD:289560
ANK repeat 233..264 CDD:293786
ANK repeat 266..295 CDD:293786
ANK 294..419 CDD:238125
ANK repeat 299..330 CDD:293786
Ank_4 300..353 CDD:290365
ANK repeat 332..363 CDD:293786
Ank_2 337..428 CDD:289560
ANK 360..485 CDD:238125
ANK repeat 365..395 CDD:293786
ANK repeat 398..427 CDD:293786
ANK repeat 431..462 CDD:293786
Ank_2 436..526 CDD:289560 2/2 (100%)
ANK repeat 464..494 CDD:293786
ANK 491..616 CDD:238125 31/101 (31%)
ANK repeat 496..527 CDD:293786 2/3 (67%)
Ank_2 501..592 CDD:289560 22/76 (29%)
ANK repeat 529..560 CDD:293786 7/30 (23%)
ANK 557..682 CDD:238125 34/133 (26%)
ANK repeat 562..590 CDD:293786 12/35 (34%)
Ank_5 582..636 CDD:290568 18/54 (33%)
ANK repeat 595..625 CDD:293786 12/30 (40%)
ANK repeat 628..657 CDD:293786 1/28 (4%)
Ank_2 633..723 CDD:289560 17/94 (18%)
ANK repeat 661..691 CDD:293786 9/29 (31%)
ANK 692..812 CDD:238125 22/124 (18%)
ANK repeat 693..724 CDD:293786 7/35 (20%)
Ank_2 698..788 CDD:289560 15/89 (17%)
ANK repeat 726..755 CDD:293786 5/28 (18%)
ANK repeat 759..788 CDD:293786 5/28 (18%)
ZU5 930..1034 CDD:128514 22/106 (21%)
Death_ank 1439..1521 CDD:260029
ankrd34baXP_689430.3 ANK 37..>140 CDD:238125 36/140 (26%)
ANK repeat 43..81 CDD:293786 12/37 (32%)
Ank_4 45..105 CDD:290365 20/59 (34%)
ANK repeat 83..115 CDD:293786 13/45 (29%)
Ank_4 84..138 CDD:290365 20/91 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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