DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and ANKRD65

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:NP_001138682.1 Gene:ANKRD65 / 441869 HGNCID:42950 Length:399 Species:Homo sapiens


Alignment Length:363 Identity:124/363 - (34%)
Similarity:159/363 - (43%) Gaps:56/363 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   277 WGKL---------SLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKN 332
            ||.|         .|.|.||.:||.::.....|.||||.|...||..:::.|||:.||:....:.
Human    42 WGHLLQAVWRGPAGLVTQLLRQGASVEERDHAGRTPLHLAVLRGHAPLVRLLLQRGAPVGAVDRA 106

  Fly   333 GLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDY----KANPN 393
            |.:|||.||...|...|.|||...|.....:...||.||.||..||..:|..||:.    .|...
Human   107 GRTALHEAAWHGHSRVAELLLQRGASAAARSGTGLTPLHWAAALGHTLLAARLLEAPGPGPAAAE 171

  Fly   394 ARALNGFTPLHIACKKNRIKMVELLIKHGANI-GATTESGLTPLHVASFMGCINIVIYLLQHEAS 457
            |....|:|..|.|....|:.::|||...||.: ||                              
Human   172 AEDARGWTAAHWAAAGGRLAVLELLAAGGAGLDGA------------------------------ 206

  Fly   458 ADLPTIRGETPLHLAARANQADIIRILL-RSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGA 521
                       |.:||.|.:...:|.|| |.|:|||....|.|.|.:|:.||....|.:||.|||
Human   207 -----------LLVAAAAGRGAALRFLLARGARVDARDGAGATALGLAAALGRSQDIEVLLGHGA 260

  Fly   522 EINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNG 586
            :...:.....||||.||..|....||:|:..|||.:|....|.||||.|.:.|...|...||..|
Human   261 DPGIRDRHGRSALHRAAARGHLLAVQLLVTQGAEVDARDTLGLTPLHHASREGHVEVAGCLLDRG 325

  Fly   587 ASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNL 624
            |.:|..|....||||:|....:...|.|||..|:||.|
Human   326 AQVDATGWLRKTPLHLAAERGHGPTVGLLLSRGASPTL 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125
ANK repeat 72..103 CDD:293786
Ank_2 77..167 CDD:289560
ANK repeat 105..136 CDD:293786
ANK repeat 138..169 CDD:293786
ANK 204..320 CDD:238125 17/51 (33%)
ANK repeat 204..231 CDD:293786
Ank_2 205..295 CDD:289560 9/26 (35%)
ANK repeat 233..264 CDD:293786
ANK repeat 266..295 CDD:293786 9/26 (35%)
ANK 294..419 CDD:238125 45/128 (35%)
ANK repeat 299..330 CDD:293786 13/30 (43%)
Ank_4 300..353 CDD:290365 22/52 (42%)
ANK repeat 332..363 CDD:293786 12/30 (40%)
Ank_2 337..428 CDD:289560 34/95 (36%)
ANK 360..485 CDD:238125 30/129 (23%)
ANK repeat 365..395 CDD:293786 12/33 (36%)
ANK repeat 398..427 CDD:293786 10/29 (34%)
ANK repeat 431..462 CDD:293786 0/30 (0%)
Ank_2 436..526 CDD:289560 24/90 (27%)
ANK repeat 464..494 CDD:293786 12/30 (40%)
ANK 491..616 CDD:238125 49/124 (40%)
ANK repeat 496..527 CDD:293786 12/30 (40%)
Ank_2 501..592 CDD:289560 37/90 (41%)
ANK repeat 529..560 CDD:293786 14/30 (47%)
ANK 557..682 CDD:238125 28/68 (41%)
ANK repeat 562..590 CDD:293786 12/27 (44%)
Ank_5 582..636 CDD:290568 19/43 (44%)
ANK repeat 595..625 CDD:293786 13/30 (43%)
ANK repeat 628..657 CDD:293786
Ank_2 633..723 CDD:289560
ANK repeat 661..691 CDD:293786
ANK 692..812 CDD:238125
ANK repeat 693..724 CDD:293786
Ank_2 698..788 CDD:289560
ANK repeat 726..755 CDD:293786
ANK repeat 759..788 CDD:293786
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
ANKRD65NP_001138682.1 ANK 1 40..69 9/26 (35%)
ANK <41..94 CDD:238125 17/51 (33%)
Ank_2 45..136 CDD:289560 32/90 (36%)
ANK repeat 45..71 CDD:293786 7/25 (28%)
ANK 69..192 CDD:238125 43/122 (35%)
ANK 2 73..102 13/28 (46%)
ANK repeat 74..104 CDD:293786 13/29 (45%)
ANK repeat 106..137 CDD:293786 12/30 (40%)
ANK 3 106..135 12/28 (43%)
ANK 4 139..168 11/28 (39%)
Ank_2 144..299 CDD:289560 61/195 (31%)
ANK 5 176..205 10/28 (36%)
ANK 6 207..231 10/23 (43%)
ANK 7 235..264 12/28 (43%)
ANK 252..355 CDD:238125 41/102 (40%)
ANK repeat 268..299 CDD:293786 14/30 (47%)
ANK 8 268..297 13/28 (46%)
Ank_2 273..364 CDD:289560 39/91 (43%)
ANK repeat 301..332 CDD:293786 13/30 (43%)
ANK 9 301..330 12/28 (43%)
ANK repeat 334..364 CDD:293786 13/30 (43%)
ANK 10 334..363 12/28 (43%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 377..399
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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