DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and Ankmy1

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:XP_006529653.1 Gene:Ankmy1 / 241158 MGIID:3045261 Length:1056 Species:Mus musculus


Alignment Length:734 Identity:165/734 - (22%)
Similarity:255/734 - (34%) Gaps:239/734 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 NGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGF-----TPLAVAMQQGHDK----------- 186
            |...|:..:.::..|:   .:..|...|.:..|:.:     |||.|.:|:...|           
Mouse   263 NSHLPMTDSLRQELDD---HIFMNEIPPFIEDEEPWLITNETPLLVKIQKQTYKFRNKDAHTSWN 324

  Fly   187 IVAVLLENDVRGKVRLPALHIA------AKKNDVN-AAKLLLQHDPNADIVSKSGFTPLHIAAHY 244
            |.|:|..|..|.....|...|:      |::.|.| ...:|..:...||:....|:|.|..||.:
Mouse   325 IPAILEGNRSRFGPSGPKEQISKKMIMKAEEGDYNWIFGILRDNLACADVADSKGYTVLAAAAMH 389

  Fly   245 GNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASR 309
            .::||..|||:..||||..:...|||         ||:|.|                  .:...:
Mouse   390 SHLDIVNLLLDFGADVNKRSDEGITP---------LSMCFL------------------QYYPCK 427

  Fly   310 SGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAA 374
            |.|..:.:..|.|.:|....|               .:.:.||.|       ..:|||..:.:..
Mouse   428 SFHPNIAERTLLQESPKSLVT---------------PKISFLLAD-------ANIDYLYDVGMPI 470

  Fly   375 HCGHVKVAKLLLDYKANPNARALNGFTP-----LHIACKKNRIKMVELLI------KHGA--NIG 426
            ..|.......|.|..|:..       ||     ||    |..:..|:.:.      ..||  |:.
Mouse   471 AGGDELKTSSLDDSLASMQ-------TPESSNMLH----KEEVSPVKTVSTDVEKESEGAAENVD 524

  Fly   427 ATT--------ESGLTPLHVASFMGC-----INIVIYLLQHEASA--DLP---------TIRGET 467
            |:|        ||          ..|     ||:...:::..|.|  .||         |:| :.
Mouse   525 ASTLYSVDTNFES----------TKCLRNYTINVSRDIMEKSAQAYSSLPQHPCFPYKGTVR-KM 578

  Fly   468 PLHLAARANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYS 532
            ...:..|.|:...|.:|||......:.:.....|.:|.:.|::..:.|||..||:.:.|...:..
Mouse   579 AQSMVERRNRWMTITLLLRRGADPNLCQVPMQALFLAVKAGDVEGVRLLLMSGAQTDIQFPPQLQ 643

  Fly   533 ALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKY-GKQNV--VQILLQNGASIDFQ-- 592
            :|                              ||||:|... |::.|  .::||....::|.:  
Mouse   644 SL------------------------------TPLHIAVSLPGEEGVKITELLLHVITNVDAKAA 678

  Fly   593 --------GKNDVTPLHVATHYNNPSIVELLLKNGSSPN---------LCARNGQCAIHIAC--- 637
                    ||.|:.|            ..|.|.|...|.         :....|:.|:|:||   
Mouse   679 DEDYVYKGGKADLLP------------SSLKLNNEPGPPKSFYSTHTFIPEEGGRTALHVACERE 731

  Fly   638 --KKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGL-TPL 698
              ||...:|...||.|.|:.|:: .||.|||.||...||..:|:.||..|. .:.....|| |.|
Mouse   732 DNKKCARDIVRLLLSHRANPNVL-WSGHSPLSLAIASGNDLVVKELLSQGADPNLPLTKGLGTAL 795

  Fly   699 HVAAQ---------EGHVLVSQILLEHGANI--------SERTRNGYTPLHMAAHYGHLDLVKFF 746
            .|...         |..:.:...|:.:||::        .:||..|     .|..||:.   |||
Mouse   796 CVVCDLVYEQQRSVENKIALIDRLISYGADVLNPVTLVQGDRTAVG-----TAVDYGYF---KFF 852

  Fly   747 IENDADIEMSSNIGYTPLH 765
                    ....|.:.|.|
Mouse   853 --------QDRKIAHCPFH 863

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125 14/69 (20%)
ANK repeat 72..103 CDD:293786
Ank_2 77..167 CDD:289560 5/28 (18%)
ANK repeat 105..136 CDD:293786
ANK repeat 138..169 CDD:293786 5/30 (17%)
ANK 204..320 CDD:238125 30/122 (25%)
ANK repeat 204..231 CDD:293786 7/33 (21%)
Ank_2 205..295 CDD:289560 28/96 (29%)
ANK repeat 233..264 CDD:293786 14/30 (47%)
ANK repeat 266..295 CDD:293786 7/28 (25%)
ANK 294..419 CDD:238125 22/129 (17%)
ANK repeat 299..330 CDD:293786 5/30 (17%)
Ank_4 300..353 CDD:290365 7/52 (13%)
ANK repeat 332..363 CDD:293786 3/30 (10%)
Ank_2 337..428 CDD:289560 19/103 (18%)
ANK 360..485 CDD:238125 32/161 (20%)
ANK repeat 365..395 CDD:293786 7/29 (24%)
ANK repeat 398..427 CDD:293786 9/41 (22%)
ANK repeat 431..462 CDD:293786 8/46 (17%)
Ank_2 436..526 CDD:289560 23/105 (22%)
ANK repeat 464..494 CDD:293786 7/29 (24%)
ANK 491..616 CDD:238125 25/137 (18%)
ANK repeat 496..527 CDD:293786 8/30 (27%)
Ank_2 501..592 CDD:289560 20/93 (22%)
ANK repeat 529..560 CDD:293786 1/30 (3%)
ANK 557..682 CDD:238125 41/151 (27%)
ANK repeat 562..590 CDD:293786 9/30 (30%)
Ank_5 582..636 CDD:290568 14/72 (19%)
ANK repeat 595..625 CDD:293786 6/38 (16%)
ANK repeat 628..657 CDD:293786 12/33 (36%)
Ank_2 633..723 CDD:289560 33/113 (29%)
ANK repeat 661..691 CDD:293786 13/30 (43%)
ANK 692..812 CDD:238125 21/92 (23%)
ANK repeat 693..724 CDD:293786 9/48 (19%)
Ank_2 698..788 CDD:289560 18/85 (21%)
ANK repeat 726..755 CDD:293786 7/28 (25%)
ANK repeat 759..788 CDD:293786 3/7 (43%)
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
Ankmy1XP_006529653.1 PLN03185 83..>184 CDD:215619
Ank_2 <373..>464 CDD:393464 33/139 (24%)
ANK repeat 378..409 CDD:293786 14/30 (47%)
PHA02875 595..>836 CDD:165206 66/283 (23%)
ANK repeat 606..641 CDD:293786 9/34 (26%)
ANK repeat 646..677 CDD:293786 10/30 (33%)
ANK repeat 720..754 CDD:293786 13/33 (39%)
ANK repeat 756..788 CDD:293786 13/31 (42%)
ANK repeat 790..824 CDD:293786 7/33 (21%)
zf-MYND 941..981 CDD:366792
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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