DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and mlt-2

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:NP_492036.2 Gene:mlt-2 / 172459 WormBaseID:WBGene00007252 Length:668 Species:Caenorhabditis elegans


Alignment Length:448 Identity:116/448 - (25%)
Similarity:194/448 - (43%) Gaps:83/448 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   475 ANQADIIRI--LLRSAKV--DAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALH 535
            |...||.:|  |||..||  |::..:..|.||:|:.:||..:::.||.:||.|:|.::...:|.|
 Worm    23 AFNGDIDKIDGLLRDKKVHIDSVDDDQVTALHIAAAMGNNKLVVRLLDYGANIHAVNHLGMTAYH 87

  Fly   536 IAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDV--T 598
            .||:||:..::..|::.||..|..|..|.|.|.|||..|..:||:.|::...... :.|..:  |
 Worm    88 YAAREGKLAVLDTLMQRGASKNQTTALGVTALTLACAGGHADVVRRLIRISNETP-RSKQSLAPT 151

  Fly   599 PLHVATHYNNPSIVELL----------LKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGA 653
            ||.|||...:|.|...|          :||  ..||.|    .::.|.|... :.:...|:..||
 Worm   152 PLIVATCSKSPQICSYLADFRVNLDESMKN--LGNLTA----LSMAIVCTPG-VYMVRTLIDLGA 209

  Fly   654 DVNIISKSGF---SPLHLAAQGGNVDMVQLLLE---YGVISAAAKNGLTPLHVAAQEGHVLVSQI 712
            .||   |.|.   :...||......|::....|   |    .:..|..:.:....:..|::..::
 Worm   210 SVN---KKGLGDKTAEELAIMLNRKDLIHFFNEKKSY----RSRMNADSDVRKEIKNDHIIEREL 267

  Fly   713 LLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFI-ENDADIEMSSNIGYTPLHQAAQQGHIMII 776
                ||    ..:||.:||..|.....::..|..: ..|:|:.|..|:..|.|..|:......||
 Worm   268 ----GA----PAQNGVSPLMYATTVRSINSAKHLVLHRDSDVNMRDNLHITSLQIASLLRVDDII 324

  Fly   777 NLLLRHKANPNALTKDGNTA-------------------LHI------ASNLGYVT--VMESLKI 814
            .|||:.:|:...:.|.|:||                   ||.      .|||...:  :.::|:.
 Worm   325 PLLLQRRADVTVVNKYGSTAYDLFLLSCDFLEPGQLRGQLHCHRPIDSKSNLNSSSSNIYKALRS 389

  Fly   815 VTSTSVINSNIGAIEEKLKVMTPE--LMQETLLSDSDDESCDDLLDHNHYKYMATDDL 870
            ....:.:.|.||....|::::.|:  |..:|....:.        ..|:||:.:.:|:
 Worm   390 QGILTKVGSQIGINSAKIELIEPKHWLAAKTKYQPAK--------LRNNYKFASVEDI 439

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125
ANK repeat 72..103 CDD:293786
Ank_2 77..167 CDD:289560
ANK repeat 105..136 CDD:293786
ANK repeat 138..169 CDD:293786
ANK 204..320 CDD:238125
ANK repeat 204..231 CDD:293786
Ank_2 205..295 CDD:289560
ANK repeat 233..264 CDD:293786
ANK repeat 266..295 CDD:293786
ANK 294..419 CDD:238125
ANK repeat 299..330 CDD:293786
Ank_4 300..353 CDD:290365
ANK repeat 332..363 CDD:293786
Ank_2 337..428 CDD:289560
ANK 360..485 CDD:238125 4/11 (36%)
ANK repeat 365..395 CDD:293786
ANK repeat 398..427 CDD:293786
ANK repeat 431..462 CDD:293786
Ank_2 436..526 CDD:289560 21/54 (39%)
ANK repeat 464..494 CDD:293786 10/22 (45%)
ANK 491..616 CDD:238125 44/136 (32%)
ANK repeat 496..527 CDD:293786 12/30 (40%)
Ank_2 501..592 CDD:289560 32/90 (36%)
ANK repeat 529..560 CDD:293786 10/30 (33%)
ANK 557..682 CDD:238125 39/139 (28%)
ANK repeat 562..590 CDD:293786 10/27 (37%)
Ank_5 582..636 CDD:290568 16/65 (25%)
ANK repeat 595..625 CDD:293786 12/41 (29%)
ANK repeat 628..657 CDD:293786 6/28 (21%)
Ank_2 633..723 CDD:289560 18/95 (19%)
ANK repeat 661..691 CDD:293786 6/35 (17%)
ANK 692..812 CDD:238125 32/147 (22%)
ANK repeat 693..724 CDD:293786 4/30 (13%)
Ank_2 698..788 CDD:289560 22/90 (24%)
ANK repeat 726..755 CDD:293786 8/29 (28%)
ANK repeat 759..788 CDD:293786 9/28 (32%)
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
mlt-2NP_492036.2 PHA02876 <9..>214 CDD:165207 65/201 (32%)
ANK repeat 51..79 CDD:293786 12/27 (44%)
Ank_2 53..135 CDD:372319 31/81 (38%)
ANK repeat 81..112 CDD:293786 10/30 (33%)
ANK repeat 144..179 CDD:293786 10/34 (29%)
ANK repeat 181..214 CDD:293786 11/42 (26%)
PHA03095 201..>351 CDD:222980 39/164 (24%)
ANK repeat 273..305 CDD:293786 9/31 (29%)
ANK repeat 307..338 CDD:293786 9/30 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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