DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and LOC100497775

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:XP_002931656.2 Gene:LOC100497775 / 100497775 -ID:- Length:772 Species:Xenopus tropicalis


Alignment Length:807 Identity:222/807 - (27%)
Similarity:373/807 - (46%) Gaps:131/807 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 LLRRGIKIDN----------ATKKGNTALHIASLAGQ-------HDVINQL--ILYNANVN-VQS 136
            |:..||.:.:          .|:|.:..:.|....|:       |..:.|:  .|||:..| |.:
 Frog    47 LIDNGIMLSDKKMVLSYYKTKTEKNSRLIDILLSTGERACRLFFHPCLKQVEPSLYNSVKNYVST 111

  Fly   137 LN-----GFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAV-------AMQQGHDKIVA 189
            :|     |...|.....|...:..:|::.:  .|..:.:....|..|       :..:...|.|.
 Frog   112 VNDSVGDGRRQLVGYLLERDKDVPKTIIKD--RPHKAQQRESLPKKVKALDEKPSYSEKEKKSVP 174

  Fly   190 VLLENDVRGKVRLPALHI--AAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATL 252
            ..:..||: :....::.:  |..|.|::..:.:|: |.:.:.|:.||.|.|||||..|:|.:...
 Frog   175 QQISKDVK-RTDSSSMTVFDAVTKGDLSILRNILR-DTDINAVNPSGETLLHIAAASGHVAVIEY 237

  Fly   253 LLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIK 317
            |:|..|.::.....:.||||.|.:.|......:||..||.|.:...|.|||||.|:.:.|..|:|
 Frog   238 LINKGAKIDCKDIKHRTPLHRAAENGHGEAVKVLLRAGAFIYSLDDDSLTPLHLAAENNHQNVVK 302

  Fly   318 HLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVA 382
            .|||:..   .:.||..:.:||||...:::...|||.||||||.|.....|||..|...||:|..
 Frog   303 ILLQEEG---RQYKNRHNFIHMAATQGNNKLMQLLLKNKAPVDAVDEKSQTALLYAVSGGHLKTV 364

  Fly   383 KLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINI 447
            |:||:..|:.::..::.      |...|..::..||:::        ..||:|            
 Frog   365 KMLLEAGASIDSSIIDA------AFATNNERIFGLLLEY--------SKGLSP------------ 403

  Fly   448 VIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINI 512
                                                   ...|.|:.:  ..||::      ..|
 Frog   404 ---------------------------------------DTMVSAVFK--AVPLNL------YGI 421

  Fly   513 IMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQN 577
            |..|:..|..|||.::.:|:.|.:||:.|:....|.|:|.||:.:..|....|.||||.:.|..:
 Frog   422 INALIDKGTNINATNDIQYTPLLLAAELGKTESAQALIEKGAQLDVRTPNMSTALHLAVQGGDAS 486

  Fly   578 VVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYL 642
            :.::|::.|.:|:..|..|.||||||..:|...:.::|:..|::.|:..:.....:|||.::..|
 Frog   487 ITKLLIRKGININIAGPGDQTPLHVAAFHNKQELADILIAAGANVNVVTKELFTPLHIASQRGNL 551

  Fly   643 EIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGH 706
            .:|..||.|.|:||...|...:||||||:||..::|||||.... .::..|:..||||:||..||
 Frog   552 HVAQSLLHHKANVNAKDKQSRTPLHLAAEGGAYELVQLLLNNKADPNSTEKDKKTPLHIAAAAGH 616

  Fly   707 VLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIE--NDADIEMSSNIGYTPLHQAAQ 769
            :.:..::|:..|..:.:..:|.||:|.||..|..::.|..::  .:.:::..:....||||.||:
 Frog   617 IEIVNVMLKGQARCAVKDMDGCTPMHYAAATGSSEIAKALLKAGKNKNVDEKNVWRKTPLHLAAE 681

  Fly   770 QGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLKIVTSTSVINSNIGAIEEKLKV 834
            .||..:|||||::.|..|||..:.:|.||.|...|:::.:::|     .|.:..      ||..:
 Frog   682 HGHSDLINLLLQNGAAINALDNNRDTPLHCACKAGHLSSVQTL-----VSWVQG------EKANL 735

  Fly   835 MTPELMQETLLSDSDDESCDDLLDHNH 861
            .....:::|.|..::..|.|   .|.|
 Frog   736 QATNGLKKTPLQVAESSSSD---AHQH 759

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125 24/131 (18%)
ANK repeat 72..103 CDD:293786 3/20 (15%)
Ank_2 77..167 CDD:289560 20/99 (20%)
ANK repeat 105..136 CDD:293786 10/40 (25%)
ANK repeat 138..169 CDD:293786 6/35 (17%)
ANK 204..320 CDD:238125 40/117 (34%)
ANK repeat 204..231 CDD:293786 5/28 (18%)
Ank_2 205..295 CDD:289560 30/91 (33%)
ANK repeat 233..264 CDD:293786 13/30 (43%)
ANK repeat 266..295 CDD:293786 11/28 (39%)
ANK 294..419 CDD:238125 43/124 (35%)
ANK repeat 299..330 CDD:293786 13/30 (43%)
Ank_4 300..353 CDD:290365 19/52 (37%)
ANK repeat 332..363 CDD:293786 14/30 (47%)
Ank_2 337..428 CDD:289560 29/90 (32%)
ANK 360..485 CDD:238125 20/124 (16%)
ANK repeat 365..395 CDD:293786 11/29 (38%)
ANK repeat 398..427 CDD:293786 4/28 (14%)
ANK repeat 431..462 CDD:293786 3/30 (10%)
Ank_2 436..526 CDD:289560 10/89 (11%)
ANK repeat 464..494 CDD:293786 2/29 (7%)
ANK 491..616 CDD:238125 39/124 (31%)
ANK repeat 496..527 CDD:293786 9/30 (30%)
Ank_2 501..592 CDD:289560 28/90 (31%)
ANK repeat 529..560 CDD:293786 10/30 (33%)
ANK 557..682 CDD:238125 45/124 (36%)
ANK repeat 562..590 CDD:293786 8/27 (30%)
Ank_5 582..636 CDD:290568 16/53 (30%)
ANK repeat 595..625 CDD:293786 11/29 (38%)
ANK repeat 628..657 CDD:293786 10/28 (36%)
Ank_2 633..723 CDD:289560 36/90 (40%)
ANK repeat 661..691 CDD:293786 13/30 (43%)
ANK 692..812 CDD:238125 41/121 (34%)
ANK repeat 693..724 CDD:293786 10/30 (33%)
Ank_2 698..788 CDD:289560 30/91 (33%)
ANK repeat 726..755 CDD:293786 8/30 (27%)
ANK repeat 759..788 CDD:293786 14/28 (50%)
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
LOC100497775XP_002931656.2 CARD 26..103 CDD:260018 10/55 (18%)
PHA02876 200..>624 CDD:165207 151/500 (30%)
ANK repeat 218..249 CDD:293786 13/30 (43%)
ANK repeat 251..282 CDD:293786 11/30 (37%)
ANK repeat 347..375 CDD:293786 11/27 (41%)
ANK repeat 441..469 CDD:293786 9/27 (33%)
ANK repeat 474..502 CDD:293786 9/27 (33%)
ANK repeat 506..535 CDD:293786 10/28 (36%)
ANK repeat 537..568 CDD:293786 11/30 (37%)
Ank_2 567..>749 CDD:423045 61/192 (32%)
ANK repeat 570..598 CDD:293786 13/27 (48%)
ANK repeat 636..669 CDD:293786 8/32 (25%)
ANK repeat 671..702 CDD:293786 16/30 (53%)
ANK repeat 704..739 CDD:293786 9/45 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1011028at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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