DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and ANKRD61

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:NP_001258629.1 Gene:ANKRD61 / 100310846 HGNCID:22467 Length:418 Species:Homo sapiens


Alignment Length:499 Identity:120/499 - (24%)
Similarity:197/499 - (39%) Gaps:145/499 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   462 TIRGETPLHLAARANQADIIRILLRSAKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAE---I 523
            |.:|...|.:.:..:..|.....|.|...:||.||..|.:.|..|...:|..:.:|.:.|.   :
Human     5 TRKGSRDLVVDSAKSLEDGPSAALHSKLYEAIMREDCTTIEVLLRNHPVNQPITILPNSASNRLL 69

  Fly   524 NAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLA-----------CKYGK-- 575
            ..|..:....:|:|||..:...:..||.:||:.......|.|.|:|.           .|.|.  
Human    70 LTQPTESIIPIHLAAKYHKAQSLLCLLRHGADPEVRDTTGLTTLNLMLLHWPVTSTTWAKPGNRT 134

  Fly   576 -------QN----VVQILLQNGASIDFQGK--NDVTPLHVATHYNNPSIVELLLKNGSSPNLCAR 627
                   ||    .::||..:||.::.||:  |..:|||:|..|....::.:|.:|         
Human   135 HRILTDIQNSSITCLRILCAHGAQVNTQGEISNKRSPLHLAIAYGCYPVLSILTQN--------- 190

  Fly   628 NGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYG--VISAA 690
                                    |||||.|:::..:|||:||...|.:|::.|:.||  |..|.
Human   191 ------------------------GADVNAINEASMTPLHMAANMLNKEMMETLIAYGANVNCAV 231

  Fly   691 AKNGLTPLHVA-----AQEGHVL---VS--QILLEHGANISERTRNGYTPLHMAAHYGHLDLVKF 745
            :..|.|||.:|     ::.|.:|   ||  ::||.|||.:                         
Human   232 SSTGNTPLKLAVCTASSKAGRLLGAGVSCIRLLLTHGAKV------------------------- 271

  Fly   746 FIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHI----ASNLGYV 806
               |..|.:     |.|.:|:|...|...||||||..:||.|.||::|.:.:::    :.|:...
Human   272 ---NAQDYK-----GQTAIHEACFGGREAIINLLLEFEANVNILTRNGESPIYMYLQRSCNVRDT 328

  Fly   807 TVMESLKIVTSTSVINSNIGAIEEKLKVMTPE--LMQETLLSDSDDE-SCDDLLDHNHYKYMATD 868
            .::..|...|....:.:|.|.:  ...:|.||  |:::||:..|... |...:...|        
Human   329 ALLARLLYHTYPLRMTNNQGIL--PAGIMLPEFRLLRDTLIKQSQKPLSLQGICKRN-------- 383

  Fly   869 DLKANYGQDQKNFDTTNTDHDLTDVSVLNKKEILP----NEMSC 908
             ::..||:..|.                :.|:.||    |.:.|
Human   384 -IRNIYGEKYKQ----------------HLKQFLPVTIWNSVYC 410

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125
ANK repeat 72..103 CDD:293786
Ank_2 77..167 CDD:289560
ANK repeat 105..136 CDD:293786
ANK repeat 138..169 CDD:293786
ANK 204..320 CDD:238125
ANK repeat 204..231 CDD:293786
Ank_2 205..295 CDD:289560
ANK repeat 233..264 CDD:293786
ANK repeat 266..295 CDD:293786
ANK 294..419 CDD:238125
ANK repeat 299..330 CDD:293786
Ank_4 300..353 CDD:290365
ANK repeat 332..363 CDD:293786
Ank_2 337..428 CDD:289560
ANK 360..485 CDD:238125 4/22 (18%)
ANK repeat 365..395 CDD:293786
ANK repeat 398..427 CDD:293786
ANK repeat 431..462 CDD:293786 120/499 (24%)
Ank_2 436..526 CDD:289560 16/66 (24%)
ANK repeat 464..494 CDD:293786 6/29 (21%)
ANK 491..616 CDD:238125 39/153 (25%)
ANK repeat 496..527 CDD:293786 7/33 (21%)
Ank_2 501..592 CDD:289560 26/117 (22%)
ANK repeat 529..560 CDD:293786 8/30 (27%)
ANK 557..682 CDD:238125 35/150 (23%)
ANK repeat 562..590 CDD:293786 12/51 (24%)
Ank_5 582..636 CDD:290568 13/55 (24%)
ANK repeat 595..625 CDD:293786 8/29 (28%)
ANK repeat 628..657 CDD:293786 4/28 (14%)
Ank_2 633..723 CDD:289560 32/101 (32%)
ANK repeat 661..691 CDD:293786 12/31 (39%)
ANK 692..812 CDD:238125 34/133 (26%)
ANK repeat 693..724 CDD:293786 14/40 (35%)
Ank_2 698..788 CDD:289560 26/99 (26%)
ANK repeat 726..755 CDD:293786 2/28 (7%)
ANK repeat 759..788 CDD:293786 13/28 (46%)
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
ANKRD61NP_001258629.1 ANK 1 27..57 10/29 (34%)
ANK <32..115 CDD:295348 22/82 (27%)
ANK 2 75..104 8/28 (29%)
ANK 79..221 CDD:238125 43/174 (25%)
ANK repeat 79..106 CDD:293786 8/26 (31%)
Ank_2 80..198 CDD:289560 35/150 (23%)
ANK repeat 108..163 CDD:293786 12/54 (22%)
ANK 3 132..161 6/28 (21%)
ANK 166..298 CDD:238125 51/197 (26%)
ANK 4 167..196 12/61 (20%)
ANK repeat 169..198 CDD:293786 12/61 (20%)
Ank_2 172..275 CDD:289560 39/163 (24%)
ANK repeat 200..232 CDD:293786 12/31 (39%)
ANK 5 200..229 11/28 (39%)
ANK repeat 234..275 CDD:293786 15/68 (22%)
ANK 6 234..273 14/66 (21%)
Ank_5 263..317 CDD:290568 24/86 (28%)
ANK 272..>351 CDD:238125 24/85 (28%)
ANK repeat 277..308 CDD:293786 14/35 (40%)
ANK 7 277..306 13/33 (39%)
ANK 8 310..343 4/32 (13%)
ANK repeat 319..345 CDD:293786 3/25 (12%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4177
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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