DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and ankk1

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:NP_001124137.1 Gene:ankk1 / 100170831 ZFINID:ZDB-GENE-071015-4 Length:733 Species:Danio rerio


Alignment Length:835 Identity:200/835 - (23%)
Similarity:329/835 - (39%) Gaps:216/835 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 KIQTRSETCAINGMALDNKNGIIKQNDATISFLRAARSGDIKKVMDFLDCGEISDINSCNANGLN 75
            |::...||||:.                       ..:.|.:.:|      |||.|.....|.|.
Zfish    47 KLKVLRETCALK-----------------------TTTNDYRNIM------EISKIGRMKFNYLI 82

  Fly    76 ALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGF 140
            :::...||... :..|.:|:| .:||....     |:.....:..:|:::     .:.:..|:..
Zfish    83 SIYGICKDPPA-LVMEYMRKG-SLDNLLSN-----HLLMWPKKFQMIHEM-----TMGMNFLHSM 135

  Fly   141 TPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPAL 205
            .|..:     |.|.                               |...:||::           
Zfish   136 KPPIL-----HLNL-------------------------------KPANILLDD----------- 153

  Fly   206 HIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYV------- 263
            |:..|.:|....|.        :..||:.|.. |:.|              :.::|||       
Zfish   154 HLHVKISDFGFIKW--------EFSSKTEFIE-HLMA--------------RGNINYVPPETLSQ 195

  Fly   264 ------AKHNITPLHVAC--------KWGKLSLCTLLLCRGAKIDAATRDGL------TPLHCAS 308
                  .|:::....:..        .:..||:..:|:    ::.:..|.|:      .|..|..
Zfish   196 NPEPPGTKYDVYSFSIIMWEILTQKRSYAGLSMTEILI----RVSSGKRPGVEKIPEDKPPECED 256

  Fly   309 RSGHVEVIKHLLQQNAPILTKTKNGLSAL-----------------------HMAAQGEHDEAAH 350
            ..|.::...:...::.|..:||......|                       ...|....|.:..
Zfish   257 MIGVMQQCWNQDSRSRPPFSKTVRLTEVLSEVLKIPDTFSRREIRKRLPEQPKKTADSSDDSSIQ 321

  Fly   351 LLL-----------DNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLH 404
            .||           ..|..|..:..|..:.||.|...|..:..:::|:..|:.|.:::.|:|||.
Zfish   322 SLLVRKDFNSFKKVVRKEHVSMLFQDNNSLLHHAVAGGDRESVQMVLNLGASVNCQSVKGYTPLI 386

  Fly   405 IACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPL 469
            :|......::..||...||::..:.....|.||.|...|......:||.::|.||.....|.|||
Zfish   387 VAVLHKFYEICSLLTDCGADVNLSDGDQWTALHFAVQAGDDRATRFLLDNKARADAKEKDGWTPL 451

  Fly   470 HLAARANQADIIRILLRSAKVDAI-AREGQ---TPLHVASRLGNINIIMLLLQHGAEINAQSNDK 530
            ||||:....:|:|||||  ::|:: .:|.|   |.|||||..|:|||:.|||..||:|:.|.|::
Zfish   452 HLAAQNGHENIVRILLR--RLDSVDVQEHQSCRTALHVASIYGHINIVKLLLNKGADIDKQDNNQ 514

  Fly   531 YSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKN 595
            .:|||:||:||...:|::|:.:||:.|.|.::.::.||.|...|                :.|  
Zfish   515 STALHLAAEEGHFRVVRLLVNSGADVNKVDEQSYSSLHFAALNG----------------YTG-- 561

  Fly   596 DVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISK 660
                           |..|||..|..||........|:|:|..|.:.||.:.|.:|...|||..|
Zfish   562 ---------------ICRLLLSKGIDPNSRTNKNWTAMHLAALKGHPEIILTLEEHQGSVNIQGK 611

  Fly   661 SGFSPLHLAAQGGNVDMVQLLLEYGV-ISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERT 724
            :|::|||||...|..::|..||..|. .:.|..||.||||:|...........|:.|.||::.:.
Zfish   612 NGWTPLHLACHHGQEEVVTGLLTAGADPNLAEDNGWTPLHLACNSSSFPSVLQLISHKANVNAQN 676

  Fly   725 RNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLL 779
            .:..||||:||...::.::|..:.|:|..||..:.|.|.|..|.|..:...:.||
Zfish   677 NSQSTPLHLAAQLSNIPIIKALLMNNAQREMQDSKGCTALTLAQQCNNSEAVELL 731

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125 16/124 (13%)
ANK repeat 72..103 CDD:293786 9/30 (30%)
Ank_2 77..167 CDD:289560 13/89 (15%)
ANK repeat 105..136 CDD:293786 2/30 (7%)
ANK repeat 138..169 CDD:293786 3/30 (10%)
ANK 204..320 CDD:238125 21/142 (15%)
ANK repeat 204..231 CDD:293786 4/26 (15%)
Ank_2 205..295 CDD:289560 16/110 (15%)
ANK repeat 233..264 CDD:293786 6/43 (14%)
ANK repeat 266..295 CDD:293786 3/36 (8%)
ANK 294..419 CDD:238125 29/164 (18%)
ANK repeat 299..330 CDD:293786 5/36 (14%)
Ank_4 300..353 CDD:290365 10/81 (12%)
ANK repeat 332..363 CDD:293786 7/64 (11%)
Ank_2 337..428 CDD:289560 24/124 (19%)
ANK 360..485 CDD:238125 38/124 (31%)
ANK repeat 365..395 CDD:293786 8/29 (28%)
ANK repeat 398..427 CDD:293786 9/28 (32%)
ANK repeat 431..462 CDD:293786 10/30 (33%)
Ank_2 436..526 CDD:289560 42/93 (45%)
ANK repeat 464..494 CDD:293786 15/30 (50%)
ANK 491..616 CDD:238125 41/128 (32%)
ANK repeat 496..527 CDD:293786 18/33 (55%)
Ank_2 501..592 CDD:289560 34/90 (38%)
ANK repeat 529..560 CDD:293786 12/30 (40%)
ANK 557..682 CDD:238125 34/124 (27%)
ANK repeat 562..590 CDD:293786 4/27 (15%)
Ank_5 582..636 CDD:290568 10/53 (19%)
ANK repeat 595..625 CDD:293786 7/29 (24%)
ANK repeat 628..657 CDD:293786 9/28 (32%)
Ank_2 633..723 CDD:289560 34/90 (38%)
ANK repeat 661..691 CDD:293786 11/30 (37%)
ANK 692..812 CDD:238125 29/88 (33%)
ANK repeat 693..724 CDD:293786 11/30 (37%)
Ank_2 698..788 CDD:289560 25/82 (30%)
ANK repeat 726..755 CDD:293786 9/28 (32%)
ANK repeat 759..788 CDD:293786 7/21 (33%)
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
ankk1NP_001124137.1 PKc_like 32..289 CDD:304357 54/356 (15%)
STYKc 33..276 CDD:214568 51/343 (15%)
ANK repeat 347..378 CDD:293786 8/30 (27%)
Ank_2 352..443 CDD:289560 26/90 (29%)
ANK 375..501 CDD:238125 48/127 (38%)
ANK repeat 381..411 CDD:293786 9/29 (31%)
ANK repeat 413..444 CDD:293786 10/30 (33%)
Ank_2 418..511 CDD:289560 42/94 (45%)
ANK 441..567 CDD:238125 56/160 (35%)
ANK repeat 446..477 CDD:293786 15/32 (47%)
ANK repeat 479..511 CDD:293786 17/31 (55%)
Ank_2 485..576 CDD:289560 42/123 (34%)
ANK 508..629 CDD:238125 46/153 (30%)
ANK repeat 513..544 CDD:293786 12/30 (40%)
ANK repeat 546..576 CDD:293786 12/62 (19%)
Ank_2 551..641 CDD:289560 35/122 (29%)
ANK repeat 581..610 CDD:293786 11/28 (39%)
ANK 607..731 CDD:238125 42/123 (34%)
ANK repeat 612..643 CDD:293786 11/30 (37%)
Ank_2 617..709 CDD:289560 32/91 (35%)
ANK repeat 645..676 CDD:293786 11/30 (37%)
ANK repeat 678..709 CDD:293786 11/30 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

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